ALEC · NASDAQ · Biotechnology

Alector

Develops brain-penetrant therapies for neurodegenerative disease through its ABC delivery platform.

$2.34
After-hours close+0.01 (+0.43%)
At close$2.33(−2.51%)

Breakdown13F · Form 4

Institutions 79.62%88.40M sharesInsiders 5.32%5.91M sharesOther 15.06%16.72M shares

Shares outstanding 111.03M · Float 77.73M · 70.0% free float

Top shareholders13F · 13D/G · Form 4

HolderShares% outstandingFormFiled
TCG Crossover Management, LLC10.00M9.01%13FMay 15, 2026
RA Capital Management, L.P.9.70M9.90%13GDec 6, 2024
BlackRock, Inc.5.78M5.20%13GApr 27, 2026
Acadian Asset Management LLC4.04M3.64%13FMay 13, 2026
Foresite Capital Management Iv, LLC3.89M3.50%13FMay 15, 2026

Institutions13F, as of Mar 31, 2026

141 holders · 88.40M shares · 29 new positions · 74 increased · 35 reduced · 22 closed

HolderShares% outstandingChg q/qFiled
TCG Crossover Management, LLC10.00M9.01%0May 15, 2026
BlackRock, Inc.7.74M6.97%+593.5KMay 13, 2026
Acadian Asset Management LLC4.04M3.64%+596.3KMay 13, 2026
Foresite Capital Management Iv, LLC3.89M3.50%0May 15, 2026
Vanguard Capital Management LLC3.68M3.31%+3.68MnewMay 15, 2026
Merck & Co., Inc.3.55M3.19%0May 13, 2026
D. E. Shaw & Co., Inc.3.33M3.00%+967.7KMay 15, 2026
683 Capital Management, LLC3.20M2.88%−150.0KMay 15, 2026

Beneficial owners13D/G · 5% or more, as filed

Holder% of classSharesFormFiled
RA Capital Management, L.P.incl. Rajeev Shah, RA Capital Healthcare Fund, L.P. +1 more9.90%9.70M13GDec 6, 2024
Arnon Rosenthal7.40%8.21M13GFeb 6, 2026
BlackRock, Inc.5.20%5.78M13GApr 27, 2026

InsidersForm 4

InsiderRoleShares% outstandingFiled
Arnon Rosenthaldirector, officer: Chief Executive Officer3.46M3.11%Aug 21, 2026
Sara Kenkare-Mitraofficer: President and Head of R&D501.7K0.45%Dec 3, 2025
Neil Lindsay Berkleyofficer: CFO & Chief Business Officer399.3K0.36%Mar 13, 2026
Gary Romanoofficer: Chief Medical Officer333.0K0.30%Mar 5, 2025
Marc Grassoofficer: Chief Financial Officer296.1K0.27%Jun 4, 2025
Richard H. Schellerdirector134.9K0.12%Jun 17, 2026
Louis J. Jr Lavignedirector128.1K0.12%Jun 17, 2026
Kristine Yaffedirector124.1K0.11%Jun 17, 2026
Elizabeth A. Garofalodirector118.7K0.11%Jun 17, 2026
Grace Wong-Saradofficer: Principal Accounting Officer115.5K0.10%Jul 9, 2026

1 ten-percent owner holds 1.91M shares by Form 4, outside the officers-and-directors figure above · 9 people have not refiled in the last 18 months (15.25M shares), so they are not in the figure above

Latest trades

DateInsiderTypeSharesAvg priceOwned after
Apr 16, 2026
Grace Wong-Saradofficer: Principal Accounting Officer
Sale1,820$2.65104,645
Mar 10, 2026
Grace Wong-Saradofficer: Principal Accounting Officer
Sale1,000$2.65106,465
Mar 2, 2026
Neil Lindsay Berkleyofficer: CFO & Chief Business Officer
Sale29,649$2.12344,660
Mar 2, 2026
Arnon Rosenthaldirector, officer: Chief Executive Officer
Sale81,864$2.122,338,176
Mar 2, 2026
Grace Wong-Saradofficer: Principal Accounting Officer
Sale8,071$2.12110,832
Mar 3, 2026
Grace Wong-Saradofficer: Principal Accounting Officer
Sale3,367$2.08107,465
Feb 26, 2026
Grace Wong-Saradofficer: Principal Accounting Officer
Sale4,079$2.50118,903
Dec 5, 2025
Grace Wong-Saradofficer: Principal Accounting Officer
Sale4,753$1.21122,982
Dec 3, 2025
Neil Lindsay Berkleyofficer: Chief Bus Ofcr & Interim CFO
Sale37,261$1.12374,309
Dec 3, 2025
Sara Kenkare-Mitraofficer: President and Head of R&D
Sale41,687$1.12501,652

CongressHouse and Senate disclosures

Not reported.