ALNY · NASDAQ · Biotechnology

Alnylam Pharmaceuticals

Develops and commercializes RNAi medicines led by the AMVUTTRA-centered TTR franchise.

$240.00
After-hours close+2.90 (+1.22%)
At close$237.10(+0.23%)

Breakdown13F · Form 4

Institutions 145.06%Insiders 0.24%

A 13F quarter can total more than the shares outstanding — sub-advisers file the same block twice, and a filer's own share count can be a quarter stale. No split is drawn from it.

Shares outstanding 133.81M · Float 133.23M · 99.6% free float

Top shareholders13F · 13D/G · Form 4

HolderShares% outstandingFormFiled
FMR LLC15.02M11.23%13FAug 13, 2026
Capital World Investors11.14M8.33%13FAug 12, 2026
BlackRock, Inc.10.91M8.15%13FAug 7, 2026
Capital Research Global Investors9.75M7.29%13FAug 12, 2026
Vanguard Portfolio Management LLC6.54M4.89%13FAug 13, 2026

Institutions13F, as of Jun 30, 2026

824 holders · 194.10M shares · 91 new positions · 412 increased · 283 reduced · 94 closed

HolderShares% outstandingChg q/qFiled
FMR LLC15.02M11.23%+444.8KAug 13, 2026
Capital World Investors11.14M8.33%+342.5KAug 12, 2026
BlackRock, Inc.10.91M8.15%+462.8KAug 7, 2026
Capital Research Global Investors9.75M7.29%+279.5KAug 12, 2026
Vanguard Portfolio Management LLC6.54M4.89%+47.1KAug 13, 2026
Vanguard Capital Management LLC6.03M4.51%+82.8KAug 13, 2026
T. Rowe Price Investment Management, Inc.5.64M4.22%+448.8KAug 14, 2026
Invesco Ltd.3.75M2.81%+970.9KAug 14, 2026

Beneficial owners13D/G · 5% or more, as filed

Holder% of classSharesFormFiled
FMR LLC11.00%14.64M13GMay 6, 2026
Capital World Investors8.20%10.92M13GMay 14, 2026
Capital Research Global Investors7.10%9.47M13GMay 14, 2026
Vanguard Capital Management5.35%7.10M13GApr 29, 2026

InsidersForm 4

InsiderRoleShares% outstandingFiled
Yvonne Greenstreetdirector, officer: Chief Executive Officer95.7K0.07%Mar 6, 2026
Jeffrey V. Poultonofficer: EVP, Chief Financial Officer61.8K0.05%Mar 6, 2026
Tolga Tangulerofficer: EVP, Chief Commercial Officer34.3K0.03%Mar 6, 2026
Amy W. Schulmandirector24.0K0.02%May 22, 2026
Kevin Joseph Fitzgeraldofficer: CSO & EVP, Head of Research20.6K0.02%Mar 6, 2026
Pushkal Gargofficer: EVP Chief R&D18.7K0.01%Mar 6, 2026
Michael W. Bonneydirector16.8K0.01%Aug 19, 2025
Bryan Supranofficer: EVP, CLO and Secretary14.6K0.01%Mar 4, 2026
Melissa McLaughlinofficer: Chief Human Resources Officer9.4K0.01%Apr 7, 2026
Robert W. Hessleinofficer: EVP, CLO and Secretary8.0K0.01%Mar 5, 2025

11 ten-percent owners hold 16.01M shares by Form 4, outside the officers-and-directors figure above · 14 people have not refiled in the last 18 months (397.3K shares), so they are not in the figure above

Latest trades

DateInsiderTypeSharesAvg priceOwned after
Jun 1, 2026
David E. I. Pyottdirector
Sale · 5 lots3,830$299.181,582
Apr 6, 2026
Melissa McLaughlinofficer: Chief Human Resources Officer
Sale · 5 lots2,286$330.429,443
Apr 2, 2026
Melissa McLaughlinofficer: Chief Human Resources Officer
Sale · 9 lots1,624$319.5911,729
Mar 5, 2026
Kevin Joseph Fitzgeraldofficer: CSO & EVP, Head of Research
Sale · 4 lots658$323.9820,569
Mar 4, 2026
Kevin Joseph Fitzgeraldofficer: CSO & EVP, Head of Research
Sale · 8 lots633$323.0821,227
Mar 4, 2026
Tolga Tangulerofficer: EVP, Chief Commercial Officer
Sale · 8 lots2,309$323.0834,297
Mar 4, 2026
Jeffrey V. Poultonofficer: EVP, Chief Financial Officer
Sale · 8 lots2,468$323.0861,805
Mar 4, 2026
Yvonne Greenstreetdirector, officer: Chief Executive Officer
Sale · 8 lots2,933$323.0895,695
Mar 5, 2026
Pushkal Gargofficer: EVP Chief R&D
Sale · 4 lots2,404$323.9618,693
Mar 4, 2026
Pushkal Gargofficer: EVP Chief R&D
Sale · 8 lots2,309$323.0821,097

CongressHouse and Senate disclosures

Not reported.