ANL · NASDAQ · Biotechnology

Adlai Nortye (ADR)

Develops clinical-stage cancer therapies targeting RAS pathways and immune responses.

$13.82
After-hours close+0.08 (+0.58%)
At close$13.74(−4.05%)
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Profile

Adlai Nortye Ltd.ANLHealth Care

Develops clinical-stage cancer-therapy candidates centered on RAS-targeting therapies and next-generation cancer immunotherapies. R&D operations span China and the United States, following a shift from generics to oncology research.

Develops clinical-stage cancer-therapy candidates in two focal areas: RAS-targeting therapies and next-generation cancer immunotherapies. Its business centers on research and development rather than commercialized medicines, with the current focus following a documented transition to innovative cancer therapies.

R&D operations span China and the United States, while the listed parent was formed as a Cayman holding company for offshore financing. The operating business began in mainland China with generic pharmaceuticals and polypeptide intermediates. In 2016, the founders redirected it toward oncology-focused R&D and rebranded it as Adlai Nortye Biopharma.

The company's clinical-stage model depends on advancing cancer-therapy candidates through clinical development.

Company facts

CEOYang (Carsten) Lu
ListedSep 29, 2023
ExchangeNASDAQ
HeadquartersNorth Brunswick, NJ
CountryCayman Islands
Employees109
CIK0001944552
ISINUS00704R1095

Key statistics

Market cap$733.6M
EPS (ttm)−$1.96
P/E (ttm)−7.05
ROE-21.8%
P/B1.02
P/S37.27
Dividend yield
Beta1.69vs XLV −0.09

Year to date +896% · Average volume (30d) 169.3K

Analysts

No analyst consensus on record.

Earnings

EPS

Estimate−$0.04
Reported−$0.04+7.9%

Revenue

Estimate$12.5M
Reported$14.7M+17.7%

History

Report dateEPS estEPSSurpriseRevenue estRevenueSurpriseNext session
Aug 14, 2026Q2 FY26−$0.04−$0.04+7.9%$12.5M$14.7M+17.7%+0.68%
Apr 10, 2026Q1 FY26−$0.11−$0.18−71.4%$10.0M$5.3M−47.0%+8.06%
Dec 29, 2025Q3 FY25−$0.18−$0.180.0%$313.2K−17.22%
Aug 7, 2025−$0.18−$0.180.0%+0.65%
View details

Financial highlights

12 quartersQ1 FY24Q2 FY24Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Revenue$745.0K$745.0K$2.5M$2.5M$7.3M$7.3M
Gross profit$745.0K$745.0K$2.5M$2.5M$7.3M$7.3M
Operating income−$14.6M−$14.6M−$8.3M−$8.3M−$2.9M−$2.9M
Net income−$13.8M−$13.8M−$8.6M−$8.6M−$2.7M−$2.7M
Diluted EPS−$1.59−$1.59−$0.81−$0.81−$0.17−$0.17
Gross margin100.0%100.0%100.0%100.0%100.0%100.0%
Operating margin-1,962.6%-1,962.6%-330.5%-330.5%-39.3%-39.3%

Fiscal years (4-quarter sums)FY22 $0 · FY23 $5.0M

Balance sheet, Jun 30, 2026Cash & short-term investments $232.8M · Total debt $26.7M · Total assets $248.4M · Shareholders' equity $214.8M

Dividends

No dividends on record.

Ownership

Institutions 21.83%11.59M sharesInsiders 33.16%17.60M sharesOther 45.01%23.89M shares

Shares outstanding 53.08M · Float

Float — provider float and free-float percent disagree.

The provider's float, free-float percent and share count do not reconcile, so the float is not shown.

Top shareholders13F · 13D/G · Form 4

HolderShares% outstandingFormFiled
Yang Lu · director, 10 percent owner, officer: CEO17.09M32.20%Form 4May 21, 2026
Venrock Healthcare Capital Partners III, L.P.9.64M6.10%13GFeb 11, 2026
ANL Talent Limited9.30M7.75%13GJan 16, 2026
VR Adviser, LLC3.21M6.05%13FMay 15, 2026
Cormorant Asset Management, LP2.90M5.19%13GMay 15, 2026

Insider tradesForm 4

DateInsiderRoleSharesAvg price
Aug 26, 2026Xiaofeng Yeofficer: CFO−5,667$14.25
Aug 24, 2026Xiaofeng Yeofficer: CFO−6,000$13.98
May 13, 2026Yang Ludirector, 10 percent owner, officer: CEO−10$13.18
View details

Peers

  • Revolution Medicines

    Broad RAS(ON) inhibitor pipeline for RAS-addicted cancers

  • Bristol-Myers Squibb

    KRAS G12C therapy and PD-1 immuno-oncology franchise

  • Amgen

    Commercial KRAS G12C inhibitor for lung and colorectal cancer

  • Merck

    PD-1 immunotherapy franchise across multiple solid tumors

CompareAfter-hours close

CompanyPriceChange
Adlai Nortye (ADR)$13.82+0.58%$733.6M37.3
Revolution Medicines$208.55+0.23%$44.19B
Bristol-Myers Squibb$66.60+0.05%$136.00B14.710.52.8+5.7%
Amgen$430.27−0.49%$233.38B26.918.46.1+9.7%
Merck$148.19−0.08%$366.18B118.717.25.5+5.1%
Median26.917.25.5+5.7%