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ANRO · NYSE · Biotechnology

Alto Neuroscience (ANRO)

Develops neuropsychiatric drug candidates for biomarker-defined patient populations.

$36.64

Pre-market+0.05 (+0.14%)

At close$36.59(+3.95%)

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Breakdown13F · 13D/G · Form 4

Institutions114 holders · as of Mar 31, 2026 · largest filers plus last quarter's tail	≈ 76.45%	26.83M shares
Insiders2 holders · as of May 15, 2026	3.07%	1.08M shares
Strategic holders1 holder · as of Jul 20, 2026	6.36%	2.23M shares
Otherremainder	≈ 14.12%	4.95M shares

35.09M company shares as of Aug 23, 2026 · institutions as of Mar 31, 2026 · holders as of their latest filing

Two share counts disagree (39.24M in the company's Sep 3, 2026 report, 35.09M elsewhere); stakes use the report.

This quarter's institutional total failed a plausibility check; shown: the largest filers plus last quarter's remainder.

Top shareholders13F · 13D/G · Form 4

Holder	Stake	Shares	Evidence
Alpha Wave Global, LPInstitution	10.57%	3.71M	13Fas of Mar 31, 2026
Commodore Capital LPInstitution	7.76%	2.72M	13Fas of Mar 31, 2026
Sirenia Capital Management LPInstitution	7.38%	2.59M	13Gfiled May 15, 2026 ↗
EcoR1 Capital, LLCStrategic	6.36%	2.23M	13Gfiled Jul 20, 2026 ↗
Vestal Point Capital, LPInstitution	5.88%	2.06M	13Fas of Mar 31, 2026
Perceptive Advisors LLCInstitution	5.73%	2.01M	13Fas of Mar 31, 2026
Spruce Street Capital LPInstitution	3.78%	1.33M	13Fas of Mar 31, 2026
Vanguard Capital Management LLCInstitution	3.44%	1.21M	13Fas of Mar 31, 2026
Franklin Resources IncInstitution	3.14%	1.10M	13Fas of Mar 31, 2026
Amit Etkin¹Insiderdirector, officer: PRESIDENT AND CEO	3.01%	1.46M	13Gfiled May 15, 2026 ↗
Vivo Capital, LLCInstitution	2.95%	1.04M	13Fas of Mar 31, 2026
Armistice Capital, LLCInstitution	2.60%	912,000	13Fas of Mar 31, 2026
Millennium Management LLCInstitution	2.34%	821,982	13Fas of Mar 31, 2026
72 Investment Holdings, LLCInstitution	1.90%	667,778	13Fas of Mar 31, 2026
BlackRock, Inc.Institution	1.90%	666,188	13Fas of Mar 31, 2026
Ikarian Capital, LLCInstitution	1.47%	515,000	13Fas of Mar 31, 2026
Point72 Asset Management, L.P.Institution	1.43%	503,087	13Fas of Mar 31, 2026
Affinity Asset Advisors, LLCInstitution	1.42%	500,000	13Fas of Mar 31, 2026
Integral Health Asset Management, LLCInstitution	1.42%	500,000	13Fas of Mar 31, 2026
VR Adviser, LLCInstitution	1.42%	500,000	13Fas of Mar 31, 2026
Driehaus Capital Management LLCInstitution	1.39%	486,726	13Fas of Mar 31, 2026
Northern Trust CorpInstitution	1.35%	473,403	13Fas of Mar 31, 2026
Jennison Associates LLCInstitution	1.10%	386,426	13Fas of Mar 31, 2026
Adage Capital Partners GP, L.L.C.Institution	1.10%	385,000	13Fas of Mar 31, 2026
Price T Rowe Associates Inc /MD/Institution	1.06%	371,208	13Fas of Mar 31, 2026

Amit Etkin's transaction reports restate only vehicles that traded; the 2024 ownership statement (1.46M) less the 406.2K net shares sold since is used instead.

13F — a manager's quarterly holdings · 13D/13G — an ownership statement filed at 5% or more

Institutions13F, as of Mar 31, 2026

114 holders · 26.83M shares · 25 new positions · 53 increased · 43 reduced · 12 closed

Holder	Shares	% outstanding	Chg q/q	Filed
Alpha Wave Global, LP	3.71M	10.57%	0	May 14, 2026
Commodore Capital LP	2.72M	7.76%	+900.0K	May 15, 2026
Vestal Point Capital, LP	2.06M	5.88%	−420.9K	May 15, 2026
Perceptive Advisors LLC	2.01M	5.73%	+225.5K	May 29, 2026
Spruce Street Capital LP	1.33M	3.78%	+1.10M	May 14, 2026
Vanguard Capital Management LLC	1.21M	3.44%	+1.21Mnew	May 15, 2026
Franklin Resources Inc	1.10M	3.14%	−17.7K	May 13, 2026
Vivo Capital, LLC	1.04M	2.95%	0	May 20, 2026

Ownership statements13D/G · 5% or more, as filed

Holder	% of class	Shares	Form	Filed
Perceptive Advisors LLC	9.99%	3.25M	13G	Feb 17, 2026 ↗
Commodore Capital LP	9.90%	3.59M	13G	May 15, 2026 ↗
Sirenia Capital Management LP	7.90%	2.59M	13G	May 15, 2026 ↗
Vestal Point Capital, LP	6.50%	2.06M	13G	May 15, 2026 ↗
BlackRock, Inc.	6.00%	2.10M	13G	Jul 27, 2026 ↗
Armistice Capital, LLC	6.00%	1.62M	13G	Feb 17, 2026 ↗
EcoR1 Capital, LLC	5.80%	2.23M	13G	Jul 20, 2026 ↗
Amit Etkin	5.40%	1.46M	13G	Nov 14, 2024 ↗

Alto Neuroscience (ANRO)

Breakdown13F · 13D/G · Form 4

Top shareholders13F · 13D/G · Form 4

Institutions13F, as of Mar 31, 2026

Ownership statements13D/G · 5% or more, as filed

Insider tradesForm 4

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