AMZNprintsminutestrendsdividendsdrawdownsP/E 28.4macronarrativesvolatilitybuybackssentiment+0.8%marginsMSFTPMI 52.1momentumdividendsflowsPMI 52.1digeststhreadsvolatilityearnings callsvolumesβ 1.24breakoutsnewsflow2s10sliquidityheadlines−1.2%breakoutsnoiseGOOGLbuybacksrevisionstrendsPMI 52.1briefstickersnoiseGDPsentimentchattertranscriptsGOOGLsentimentvolatilitybuybacksMSFTwhispersMETAsessionsyield curves13FfuturesdowngradesPMI 52.1headlinesthe tapeflowsdowngradesfutures+0.8%earnings callstranscriptsclosesgammacatalystsrevisionsvolatilitysentimentchatter+2.41%earnings callssentimentfilingstrends10y 4.21%cyclesbuybackswiresspx 0dtewhisperstickersQ3trendsnewsflowearnings callsWTI 78.2sentimentnoisethreadsrumorsnarrativesFOMCconsensusestimatesmomentumYoY +18%tickersmomentumprintsβ 1.24revisions

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PCEliquiditysentimentbreakoutsdowngradesP/E 28.4threadsAAPLSPXvolatilityNDXflowscyclesliquidityestimatesEPS 4.12

Delisting risk

APRE · NASDAQ · Biotechnology

Aprea Therapeutics (APRE)

Develops oral DNA-damage-response inhibitors for biomarker-defined solid tumors.

$0.8205

Pre-market−0.02 (−2.86%)

At close$0.8447(+1.08%)

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Breakdown13F · 13D/G · Form 4

Institutions22 holders · as of Mar 31, 2026	17.82%	2.24M shares
Insiders11 holders · as of Jun 17, 2026	15.69%	1.98M shares
Otherremainder	66.49%	8.37M shares

12.59M company shares as of Sep 3, 2026 · institutions as of Mar 31, 2026 · holders as of their latest filing

Top shareholders13F · 13D/G · Form 4

Holder	Stake	Shares	Evidence
Squadron Master Fund LPInstitution	10.10%	1.27M	13Gfiled Apr 7, 2026 ↗
Soleus Private Equity Fund III, L.P.Institution	10.10%	1.27M	13Gfiled Apr 1, 2026 ↗
Orin HirschmanInsider	9.42%	1.19M	13Gfiled Apr 27, 2026 ↗
Aigh Capital Management LLCInstitution	8.07%	1.02M	13Fas of Mar 31, 2026
Oren GiladInsiderdirector, officer: President/CEO	3.13%	393,895	Form 4filed Mar 16, 2026 ↗
Vestal Point Capital, LPInstitution	2.78%	350,000	13Fas of Mar 31, 2026
Sphera Funds Management Ltd.Institution	2.14%	270,000	13Fas of Mar 31, 2026
Marc DueyInsiderdirector	2.06%	259,312	Form 4filed Jun 17, 2026 ↗
Nantahala Capital Management, LLCInstitution	1.63%	205,760	13Fas of Mar 31, 2026
Geode Capital Management, LLCInstitution	0.95%	119,131	13Fas of Mar 31, 2026
Scientech Research LLCInstitution	0.48%	60,281	13Fas of Mar 31, 2026
Bernd R. SeizingerInsiderdirector	0.39%	48,910	Form 4filed Jun 17, 2026 ↗
John P. HamillInsiderofficer: SrVP/CFO/Prin Fin & Acct Ofcr	0.35%	43,528	Form 4filed Mar 16, 2026 ↗
BNP Paribas Arbitrage, SNCInstitution	0.32%	39,817	13Fas of Mar 31, 2026
Vanguard Fiduciary Trust CoInstitution	0.31%	38,464	13Fas of Mar 31, 2026
Renaissance Technologies LLCInstitution	0.20%	25,100	13Fas of Mar 31, 2026
Morgan StanleyInstitution	0.18%	22,330	13Fas of Mar 31, 2026
LPL Financial LLCInstitution	0.17%	21,052	13Fas of Mar 31, 2026
Vanguard Capital Management LLCInstitution	0.16%	19,622	13Fas of Mar 31, 2026
Hightower Advisors, LLCInstitution	0.11%	13,864	13Fas of Mar 31, 2026
Two Sigma Securities, LLCInstitution	0.11%	13,500	13Fas of Mar 31, 2026
John B. Iii HennemanInsiderdirector	0.11%	13,364	Form 4filed Jun 17, 2026 ↗
Susquehanna International Group, LLPInstitution	0.10%	13,018	13Fas of Mar 31, 2026
Rifat PamukcuInsiderdirector	0.07%	9,096	Form 4filed Jun 17, 2026 ↗
BlackRock, Inc.Institution	0.07%	8,504	13Fas of Mar 31, 2026

13F — a manager's quarterly holdings · 13D/13G — an ownership statement filed at 5% or more · Form 4 — an insider's transaction report

Institutions13F, as of Mar 31, 2026

22 holders · 2.24M shares · 7 new positions · 11 increased · 5 reduced · 7 closed

Holder	Shares	% outstanding	Chg q/q	Filed
Aigh Capital Management LLC	1.02M	8.07%	+645.0K	Apr 30, 2026
Vestal Point Capital, LP	350.0K	2.78%	+350.0Knew	May 15, 2026
Sphera Funds Management Ltd.	270.0K	2.14%	0	May 15, 2026
Nantahala Capital Management, LLC	205.8K	1.63%	0	May 15, 2026
Geode Capital Management, LLC	119.1K	0.95%	+78.2K	May 15, 2026
Scientech Research LLC	60.3K	0.48%	+60.3Knew	May 15, 2026
BNP Paribas Arbitrage, SNC	39.8K	0.32%	+12.5K	May 12, 2026
Vanguard Fiduciary Trust Co	38.5K	0.31%	+38.5Knew	May 8, 2026

Ownership statements13D/G · 5% or more, as filed

Holder	% of class	Shares	Form	Filed
Jon M. Plexicoincl. Stonepine Capital Management, LLC, Stonepine Capital, L.P. +1 more	11.00%	365.4K	13G	Oct 10, 2024 ↗
Soleus Private Equity Fund III, L.P.	9.99%	1.27M	13G	Apr 1, 2026 ↗
Vestal Point Capital, LP	9.90%		13G	May 15, 2026 ↗
Orin Hirschman	9.90%	1.19M	13G	Apr 27, 2026 ↗
Squadron Master Fund LP	9.90%	1.27M	13G	Apr 7, 2026 ↗
Lytton Laurence W	9.90%	681.8K	13G	Nov 17, 2025 ↗
Sio Capital Management, LLC	5.09%	276.6K	13G	Feb 10, 2025 ↗

Insider tradesForm 4

Latest trades

Date	Insider	Type	Shares	Avg price	Owned after
Mar 31, 2026	Richard Petersdirector	Purchase · 2 lots	247,830	$0.3420	247,830
Mar 31, 2026	John P. Hamillofficer: SrVP/CFO/Prin Fin & Acct Ofcr	Purchase · 2 lots	61,956	$0.3420	61,956
Jan 30, 2026	John P. Hamillofficer: SrVP/CFO/Prin Fin & Acct Ofcr	Purchase · 2 lots	11,400	$0.8275	39,133
Jan 30, 2026	Oren Giladdirector, officer: President/CEO	Purchase · 2 lots	56,200	$0.8275	401,820
Dec 10, 2025	Oren Giladdirector, officer: President/CEO	Purchase · 2 lots	42,918	$0.5201	42,918
Dec 10, 2025	John P. Hamillofficer: SrVP/CFO/Prin Fin & Acct Ofcr	Purchase · 2 lots	10,000	$1.10	32,733
Dec 10, 2025	Marc Dueydirector	Purchase · 2 lots	42,918	$1.10	277,614

CongressHouse and Senate disclosures

Not reported.