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AVXL · NASDAQ · Biotechnology

Anavex Life Sciences

Develops oral investigational therapies for neurodegenerative and neurodevelopmental diseases.

$2.99
After-hours close+0.00 (+0.14%)
At close$2.99(−4.63%)
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Profile

Anavex Life Sciences Corp.AVXLHealth Care

Develops oral investigational therapies for neurodegenerative and neurodevelopmental diseases, led by blarcamesine. The pipeline remains clinical-stage and pre-revenue, with no marketed therapy.

Built from a former online-photofinishing business, the company pivoted to drug development. It develops oral, investigational therapies for neurodegenerative and neurodevelopmental diseases, with blarcamesine as its central clinical candidate. Programs include Alzheimer’s disease, Parkinson’s disease, and Rett syndrome.

Clinical studies, translational science, and regulatory pathways form its stated approach. A European marketing-authorisation application for blarcamesine in early Alzheimer’s received a negative CHMP opinion, and re-examination was requested.

Pre-revenue since inception, the business has no marketed therapy. It depends on clinical development, regulatory review, future commercialization routes or partnerships, and continued periodic-reporting compliance.

Company facts

CEOTerrie Kellmeyer, PhD
ListedAug 2, 2006
ExchangeNASDAQ
HeadquartersNew York, NY
CountryUnited States
Employees34
CIK0001314052
ISINUS0327973006

Key statistics

Market cap$277.1M
EPS (ttm)−$0.1400
P/E (ttm)−21.36
ROE-21.1%
P/B2.43
P/S0.00
Dividend yield
Beta1.80vs XLV 0.81

Year to date −18.9% · Average volume (30d) 926.5K

Analysts

Price target, next 12 months$11.00+267.9%Median of 13 analysts · vs the Aug 28 close
ConsensusBuy11 of 13 analysts rate it buy or better

Ratings

Target range

Latest analyst notes

DateFirmActionPrior ratingRating
Oct 24, 2025Jones TradingDowngradeBuyHold

Earnings

EPS

Estimate−$0.11
ReportedDue Nov 24, 2026

Revenue

Estimate
ReportedDue Nov 24, 2026

History

Report dateEPS estEPSSurpriseRevenue estRevenueSurpriseNext session
Aug 28, 2026Q3 FY26−$0.08−$0.03+62.5%
Aug 25, 2026Q3 FY26−$0.08−$0.080.0%+14.47%
Aug 24, 2026Q3 FY26−$0.08−$0.06+25.0%−4.01%
Aug 21, 2026Q3 FY26−$0.08−$0.06+25.0%+3.51%
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Financial highlights

12 quartersQ2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26Q3 FY26
Revenue$0$0$0$0$0$0
Gross profit$0$0$0$0$0$0
Operating income−$12.5M−$14.5M−$10.8M−$6.8M−$6.5M$6.7M
Net income−$11.2M−$13.2M−$9.8M−$5.7M−$5.3M$7.9M
Diluted EPS−$0.13−$0.16−$0.11−$0.06−$0.06$0.09
Gross margin
Operating margin

Fiscal years (4-quarter sums)FY21 $0 · FY22 $0 · FY23 $0 · FY24 $0 · FY25 $0

Balance sheet, Jun 30, 2026Cash & short-term investments $118.3M · Total debt $0 · Total assets $120.1M · Shareholders' equity $112.4M

Dividends

No dividends on record.

Ownership

Institutions 40.69%37.71M sharesInsiders 1.68%1.55M sharesOther 57.63%53.41M shares

Shares outstanding 92.67M · Float 89.78M · 96.9% free float

Top shareholders13F · 13D/G · Form 4

HolderShares% outstandingFormFiled
BlackRock, Inc.8.06M8.69%13FAug 7, 2026
Vanguard Capital Management4.66M5.03%13GJul 31, 2026
Two Sigma Investments, LP3.05M3.29%13FAug 14, 2026
Geode Capital Management, LLC2.41M2.60%13FAug 12, 2026
State Street Corp1.92M2.07%13FAug 7, 2026

Insider tradesForm 4

No open-market trades in the last 12 months.

View details

Peers

  • Eli Lilly

    FDA-approved early-Alzheimer's anti-amyloid therapy

  • Biogen

    Co-commercializes FDA-approved LEQEMBI for early Alzheimer's

  • Acadia Pharmaceuticals

    Markets FDA-approved DAYBUE for Rett syndrome

CompareAfter-hours close

CompanyPriceChange
Anavex Life Sciences$2.99+0.14%$277.1M
Eli Lilly$1,173.00−0.08%$1.10T39.428.713.9+47.7%
Biogen$218.19−0.14%$32.28B38.716.53.2+3.4%
Acadia Pharmaceuticals$29.17+0.18%$4.98B13.132.74.4+16.4%
Median38.728.74.4+16.4%