BBOT · NASDAQ · Biotechnology

BridgeBio Oncology Therapeutics

Develops small-molecule therapies for RAS- and PI3K-driven malignancies.

$8.91
After-hours close+0.19 (+2.18%)
At close$8.72(−5.01%)
Loading prices…

Profile

BridgeBio Oncology Therapeutics Inc.BBOTHealth Care

Develops small-molecule therapies for RAS- and PI3K-driven malignancies. The clinical-stage precision-oncology business separated from BridgeBio before its Nasdaq de-SPAC listing.

Develops small-molecule therapies for RAS- and PI3K-driven malignancies. The clinical-stage business grew from TheRas, established by BridgeBio Pharma in 2016, and began significant operations independently after separating from BridgeBio.

Trades on Nasdaq as the public successor to Helix Acquisition Corp. II, following a 2025 de-SPAC transaction. Its operating focus remains precision oncology, with development centered on novel small molecules for RAS and PI3K malignancies. Pedro J. Beltran serves as president and chief executive officer, with Neil Kumar as executive chairman. Progress depends on advancing the clinical-stage pipeline for those molecular targets.

Company facts

CEOPedro J. Beltran, Ph.D.
ListedAug 12, 2025
ExchangeNASDAQ
HeadquartersSouth San Francisco, CA
CountryUnited States
Employees106
CIK0001869105
ISINUS1079241022

Key statistics

Market cap$700.1M
EPS (ttm)−$709.70
P/E (ttm)−0.0123
ROE-46.9%
P/B0.0022
P/S0.00
Dividend yield
Beta1.44vs XLV 0.38

Year to date −29.0% · Average volume (30d) 267.1K

Analysts

Price target, next 12 months$23.00+163.2%Median of 4 analysts · vs the Aug 28 close
ConsensusBuy4 of 4 analysts rate it buy or better

Ratings

Target range

Latest analyst notes

DateFirmActionRatingPrior targetTarget
Jul 8, 2026UBSDowngradeOverweight
May 11, 2026Canaccord GenuityTarget$23
Feb 10, 2026Stifel NicolausTarget$23
Jan 9, 2026Raymond JamesTarget$24
Jan 8, 2026Morgan StanleyTarget$20$18

Earnings

EPS

Estimate−$0.56
ReportedDue Nov 11, 2026

Revenue

Estimate
ReportedDue Nov 11, 2026

History

Report dateEPS estEPSSurpriseRevenue estRevenueSurpriseNext session
Aug 11, 2026Q2 FY26−$0.57−$0.71−24.8%+2.39%
Jun 4, 2026Q1 FY26−$0.51−$0.53−2.8%−5.10%
May 12, 2026Q1 FY26−$0.51−$0.53−2.8%−0.62%
Mar 5, 2026Q4 FY25−$0.63−$0.48+24.2%+5.36%
View details

Financial highlights

12 quartersQ1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Revenue$0$0$0$0$0$0
Gross profit$0$0$0$0−$186.0K$0
Operating income−$23.1M−$30.1M−$49.2M−$43.4M−$46.2M−$60.2M
Net income−$22.1M−$28.4M−$44.8M−$38.8M−$42.1M−$56.5M
Diluted EPS−$0.94−$1.21−$1.90−$1.25−$1.35−$705.20
Gross margin
Operating margin

Fiscal years (4-quarter sums)FY24 $0 · FY25 $0

Balance sheet, Jun 30, 2026Cash & short-term investments $225.7M · Total debt $2.5M · Total assets $376.7M · Shareholders' equity $323.1M

Dividends

No dividends on record.

Ownership

Institutions 71.70%57.44M sharesInsiders 0.28%221.8K sharesOther 28.02%22.45M shares

Shares outstanding 80.11M · Float 453.0K · 0.6% free float

A Form 4 total here can count shares the filer formally disclaims — an award voted by proxy, for instance — which the holder's own Schedule 13D/G excludes, so where the two disagree the schedule's smaller figure is used.

Top shareholders13F · 13D/G · Form 4

HolderShares% outstandingFormFiled
Cormorant Asset Management, LP17.88M22.32%13FMay 15, 2026
BridgeBio Pharma LLC · 10 percent owner13.88M17.32%Form 4Oct 16, 2025
Bihua Chen7.39M31.59%13DMar 4, 2025
Deerfield Management Company, L.P. (Series C)4.89M6.10%13FMay 15, 2026
BC Global Opportunities IX LP4.37M5.50%13GSep 3, 2025

Insider tradesForm 4

No open-market trades in the last 12 months.

View details

Peers

  • Revolution Medicines

    Broad RAS(ON) portfolio across KRAS G12C, G12V, and pan-RAS tumors

  • Amgen

    Approved KRAS G12C therapy in lung and colorectal cancer

  • Bristol-Myers Squibb

    Approved KRAS G12C therapy in lung and colorectal cancer

  • Eli Lilly

    Second-generation KRAS G12C inhibitor in NSCLC and CRC studies

  • Novartis (ADR)

    Approved PI3Kα therapy for PIK3CA-mutant HR+/HER2- breast cancer

  • AstraZeneca (ADR)

    Approved AKT therapy for biomarker-altered HR-positive breast cancer

  • Relay Therapeutics

    Phase 3 mutant-selective PI3Kα therapy for HR+/HER2- breast cancer

  • Celcuity

    PI3K/mTOR therapy for HR+/HER2- advanced breast cancer

CompareAfter-hours close

CompanyPriceChange
BridgeBio Oncology Therapeutics$8.91+2.18%$700.1M
Revolution Medicines$208.55+0.23%$44.19B
Amgen$430.27−0.49%$233.38B26.918.46.1+9.7%
Bristol-Myers Squibb$66.60+0.05%$136.00B14.710.52.8+5.7%
Eli Lilly$1,173.00−0.08%$1.10T39.428.713.9+47.7%
Novartis (ADR)$153.810.00%$292.35B23.216.45.3+0.9%
AstraZeneca (ADR)$161.79−0.55%$252.33B24.415.24.1+6.4%
Relay Therapeutics$19.10+1.82%$4.11B397.4−48.3%
Celcuity$90.10+1.81%$4.31B
Median24.416.45.7+6.1%