BCRX · NASDAQ · Biotechnology

BioCryst Pharmaceuticals

Commercializes oral ORLADEYO and develops injectable navenibart for hereditary angioedema.

$9.82
After-hours close0.00 (0.00%)
At close$9.82(−0.51%)

Breakdown13F · Form 4

Institutions 104.74%Insiders 1.71%

A 13F quarter can total more than the shares outstanding — sub-advisers file the same block twice, and a filer's own share count can be a quarter stale. No split is drawn from it.

Shares outstanding 254.16M · Float 214.93M · 84.6% free float

Top shareholders13F · 13D/G · Form 4

HolderShares% outstandingFormFiled
BlackRock, Inc.23.89M9.40%13FAug 7, 2026
Ra Capital Management, L.P.15.83M6.23%13FAug 14, 2026
State Street Corp15.19M5.98%13FAug 7, 2026
Deerfield Management Company, L.P. (Series C)15.10M5.94%13FAug 14, 2026
Deerfield Mgmt, L.P.14.34M6.81%13GFeb 12, 2026

Institutions13F, as of Jun 30, 2026

334 holders · 266.21M shares · 58 new positions · 191 increased · 87 reduced · 40 closed

HolderShares% outstandingChg q/qFiled
BlackRock, Inc.23.89M9.40%+1.24MAug 7, 2026
Ra Capital Management, L.P.15.83M6.23%0Aug 14, 2026
State Street Corp15.19M5.98%+2.98MAug 7, 2026
Deerfield Management Company, L.P. (Series C)15.10M5.94%+58.4KAug 14, 2026
Vanguard Capital Management LLC11.36M4.47%+228.5KAug 13, 2026
Vanguard Portfolio Management LLC11.14M4.38%−105.5KAug 13, 2026
TCG Crossover Management, LLC11.02M4.34%0Aug 14, 2026
Perceptive Advisors LLC10.31M4.06%+2.87MAug 14, 2026

Beneficial owners13D/G · 5% or more, as filed

Holder% of classSharesFormFiled
BlackRock, Inc.8.40%17.48M13GApr 17, 2025
RA Capital Management, L.P.7.30%15.30M13GNov 12, 2025
Deerfield Mgmt, L.P.6.81%14.34M13GFeb 12, 2026
Vanguard Capital Management5.16%12.96M13GApr 29, 2026

InsidersForm 4

InsiderRoleShares% outstandingFiled
Jon P. Stonehousedirector1.38M0.54%Jun 15, 2026
Charles K. Gayerofficer: President and CCO892.5K0.35%Dec 23, 2025
Alane P. Barnesofficer: Chief Legal Officer400.7K0.16%May 15, 2026
Helen M. Thackrayofficer: Chief R&D Officer377.3K0.15%Apr 2, 2025
Babar Ghiasofficer: Chief Financial Officer268.7K0.11%Dec 19, 2025
Ronald Dullingerofficer: Chief Commercial Officer258.4K0.10%Jan 9, 2026
Sandeep Menonofficer: Chief R&D Officer205.2K0.08%Apr 7, 2026
Vincent Milanodirector108.5K0.04%Jun 15, 2026
Nancy J. Hutsondirector99.1K0.04%Jun 16, 2025
Theresa Heggiedirector80.6K0.03%Jun 15, 2026

7 ten-percent owners hold 7.26M shares by Form 4, outside the officers-and-directors figure above · 23 people have not refiled in the last 18 months (3.01M shares), so they are not in the figure above

Latest trades

DateInsiderTypeSharesAvg priceOwned after
May 18, 2026
Amy E. McKeedirector
Sale11,180$8.9731,252
May 13, 2026
Alane P. Barnesofficer: Chief Legal Officer
Sale62,500$9.54400,703
Mar 20, 2026
Theresa Heggiedirector
Sale49,933$10.1165,352
Mar 16, 2026
Alane P. Barnesofficer: Chief Legal Officer
Sale150,000$9.15400,703
Dec 22, 2025
Alane P. Barnesofficer: Chief Legal Officer
Sale21,773$7.65398,751
Dec 15, 2025
Alane P. Barnesofficer: Chief Legal Officer
Sale21,210$7.65315,726
Dec 3, 2025
Alane P. Barnesofficer: Chief Legal Officer
Sale19,770$7.65345,476
Dec 2, 2025
Alane P. Barnesofficer: Chief Legal Officer
Sale50,906$7.21365,246
Dec 1, 2025
Alane P. Barnesofficer: Chief Legal Officer
Sale91,004$7.10416,152
Nov 13, 2025
Machelle Sandersdirector
Sale9,600$7.1430,642

CongressHouse and Senate disclosures

Not reported.