CAI · NASDAQ · Biotechnology

Caris Life Sciences

Delivers tissue and blood molecular profiling for oncology care and biopharma research.

$25.63
After-hours close−0.01 (−0.03%)
At close$25.64(−2.82%)
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Profile

Caris Life Sciences, Inc.CAIHealth Care

Combines tissue and blood molecular profiling with sequencing, AI/ML, and a clinico-genomic dataset. MI Profile and Caris Assure serve clinical oncology, while biopharma clients use testing, data and bioinformatics, and discovery services.

MI Profile provides tissue-based molecular profiling, while Caris Assure provides blood-based profiling for oncology. Sequencing, AI/ML, and a clinico-genomic dataset sit behind the platform’s clinical molecular-profiling services.

Biopharma clients use Caris for testing, data and bioinformatics, and discovery work. Operations extend from Irving to locations in Phoenix, New York, Cambridge, Basel, and Tokyo, connecting a clinical portfolio with biopharma services.

Founded in 2008 through the acquisition of Molecular Profiling Institute, the business remains founder-led by David Dean Halbert. Its precision-medicine platform combines molecular information with AI/ML for oncology-focused clinical and biopharma use.

Company facts

CEODavid Dean Halbert
ListedJun 18, 2025
ExchangeNASDAQ
HeadquartersIrving, TX
CountryUnited States
Employees1,846
CIK0002019410
ISINUS1421521071

Key statistics

Market cap$7.25B
EPS (ttm)$0.3579
P/E (ttm)71.61
ROE18.8%
P/B12.25
P/S7.32
Dividend yield
Beta1.37vs XLV 0.80

Year to date −5.0% · Average volume (30d) 5.1M

Analysts

Price target, next 12 months$24.00−6.4%Median of 7 analysts · vs the Aug 28 close
ConsensusBuy6 of 7 analysts rate it buy or better

Ratings

Target range

Latest analyst notes

DateFirmActionRatingPrior targetTarget
Aug 7, 2026BTIGReiterateBuy$32$33
Aug 6, 2026Evercore ISIReiterateOutperform$25$26
Jul 6, 2026Evercore ISITarget$38$25
May 8, 2026Robert W. BairdTarget$26$22
May 8, 2026BTIGReiterateBuy$45$32

Earnings

EPS

Estimate$0.03
ReportedDue Nov 4, 2026

Revenue

Estimate$255.5M
ReportedDue Nov 4, 2026

History

Report dateEPS estEPSSurpriseRevenue estRevenueSurpriseNext session
Aug 5, 2026Q2 FY26$0.01$0.00−139.2%$238.1M$263.7M+10.8%+21.58%
May 7, 2026Q1 FY26−$0.02$0.00+92.5%$209.4M$216.2M+3.2%−18.60%
Feb 26, 2026Q4 FY25−$0.02$0.28+1,500.0%$240.4M$292.9M+21.8%+4.68%
Nov 5, 2025Q3 FY25−$0.08$0.08+200.0%$280.9M$216.8M−22.8%−15.75%
View details

Financial highlights

12 quartersQ1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Revenue$120.9M$181.4M$216.8M$292.9M$216.2M$263.7M
Gross profit$57.1M$113.7M$147.5M$220.9M$141.3M$179.6M
Operating income−$58.0M$18.0M$32.6M$88.4M$5.3M$26.9M
Net income−$102.6M−$71.8M$24.3M$82.0M−$510.0K−$637.0K
Diluted EPS−$0.40−$1.87$0.08$0.28−$0.00−$0.00
Gross margin47.2%62.7%68.0%75.4%65.4%68.1%
Operating margin-47.9%9.9%15.1%30.2%2.4%10.2%

Fiscal years (4-quarter sums)FY18 $432.1M · FY19 $424.4M · FY20 $324.1M · FY24 $412.3M · FY25 $812.0M

Revenue by product · Q2 FY26

Pharma Research And Development Services$11.5M · 100%

Revenue by geography · Q2 FY26

United States$261.6M · 99%
Non-US$2.1M · 1%

Balance sheet, Jun 30, 2026Cash & short-term investments $793.1M · Total debt $452.4M · Total assets $1.23B · Shareholders' equity $591.7M

Dividends

No dividends on record.

Ownership

Institutions 52.96%Insiders 48.68%

Institutions and insiders are filed separately and overlap, so together they can pass the whole company. No split is drawn from them.

Shares outstanding 282.68M · Float 11.29M · 4.0% free float

A Form 4 total here can count shares the filer formally disclaims — an award voted by proxy, for instance — which the holder's own Schedule 13D/G excludes, so where the two disagree the schedule's smaller figure is used.

Top shareholders13F · 13D/G · Form 4

HolderShares% outstandingFormFiled
David D. Halbert · director, 10 percent owner, officer: See Remarks123.60M43.72%Form 4May 18, 2026
FMR LLC30.92M10.94%13FAug 13, 2026
TSSP Sub-Fund HoldCo, LLC23.17M8.30%13GJul 28, 2025
J H Whitney VI L P18.26M6.50%13GMay 12, 2026
ADAPT I Ltd. · 10 percent owner16.94M5.99%Form 4Jun 23, 2025

Insider tradesForm 4

DateInsiderRoleSharesAvg price
May 15, 2026Jon Halbertdirector+68,000$14.56
May 11, 2026Jeff L. Vacircadirector+31,050$16.15
Dec 11, 2025Luke Thomas Powerofficer: See Remarks−62,250$26.58
Nov 7, 2025David Baxley Spetzlerofficer: President+400$23.85
Nov 7, 2025John Russel Dentonofficer: See Remarks+4,184$24.09
View details

Peers

  • Tempus AI

    Genomic profiling, liquid biopsy, MRD, and AI/data services

  • Guardant Health

    Blood-based oncology profiling, monitoring, screening, and biopharma data

  • Natera

    ctDNA MRD testing and precision-medicine diagnostics

  • GRAIL

    Multi-cancer early detection from a blood draw

  • NeoGenomics

    Oncology diagnostics spanning NGS profiling, liquid biopsy, and MRD

CompareAfter-hours close

CompanyPriceChange
Caris Life Sciences$25.63−0.03%$7.25B71.6101.67.3+45.4%
Tempus AI$63.44−0.89%$11.22B7.8+21.6%
Guardant Health$161.50−0.03%$21.67B18.3+44.3%
Natera$325.30−0.26%$46.73B17.3+37.7%
GRAIL$80.00−0.01%$3.43B20.8+25.7%
NeoGenomics$18.20+0.86%$463.8M64.90.6+11.2%
Median64.917.3+25.7%