CAMP · NASDAQ · Biotechnology

CAMP4 Therapeutics (CAMP)

Antisense RNA medicines designed to restore protein expression in genetic diseases.

$3.83
Pre-market+0.03 (+0.79%)
At close$3.80(+0.26%)
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CAMP4 Therapeutics CorporationCAMPHealth Care

Develops antisense oligonucleotide medicines that increase protein expression from a functioning gene copy, using its RAP Platform to map regulatory RNAs. The business is pre-commercial, with research collaborations and potential licensing economics supplying revenue rather than product sales.

Develops antisense oligonucleotides through the RAP Platform, which maps locally acting regulatory RNAs and designs gene-specific candidates to increase protein output from a patient’s functioning gene copy. The approach targets haploinsufficient and partial loss-of-function disorders, with research and early candidate discovery also carried out for collaborators. Operations are primarily in the United States, alongside an Australian subsidiary and an international trial strategy.

CMP-002, the program for SYNGAP1-related disorder, is internally prioritized and designed to raise SYNGAP protein levels; the urea-cycle-disorders program is being considered for partnership after internal investment paused. No therapy is approved or commercially marketed. Revenue comes from research funding and collaboration economics, while partners can take responsibility for later development, regulatory work, manufacturing, and commercialization.

Company facts

CEOJosh Mandel-Brehm
ListedOct 11, 2024
ExchangeNASDAQ
HeadquartersCambridge, MA
CountryUnited States
Employees53
CIK0001736730
ISINUS13463J1016

Market cap$80.7M
EPS (ttm)−$2.23
P/E (ttm)−1.70
ROE-314.1%
P/B−317.65
P/S19.14
Dividend yieldDiv yield
Beta1.84vs XLV −0.09

Unavailable right now.

EPSReportedEstimate

Nov '24Mar '25May '25Aug '25Nov '25Mar '26May '26Aug '26
Reported−$24.19−$2.83−$0.62−$0.62−$0.55−$0.87−$0.32−$0.58
Estimate−$1.07−$0.91−$0.70−$0.67−$0.47−$0.31−$0.21−$0.21
Surprise−2,153.6%−211.0%+11.4%+7.5%−17.0%−180.6%−52.4%−174.3%

RevenueReportedEstimate

Nov '24Mar '25May '25Aug '25Nov '25Mar '26May '26Aug '26
Reported$652.0K$858.0K$1.5M$795.0K$300.0K$1.3M$1.8M
Estimate$250.0K$33.3K$420.2K$128.0K$433.3K$475.2K$1.1M$1.6M
Surprise+1,856.2%+104.2%+1,069.5%+83.5%−36.9%+15.7%+9.8%
Estimate−$0.21
Reported−$0.58−174.3%
Estimate$1.6M
Reported$1.8M+9.8%
View details

Current ratio470.30%

ProfitabilityRevenueNet incomeNet margin

Q3 FY24Q4 FY24Q1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Revenue$0$652.0K$858.0K$1.5M$795.0K$348.0K$1.3M$1.8M
Net income−$13.5M−$13.3M−$12.4M−$12.6M−$15.1M−$40.3M−$18.3M−$33.5M
Net margin0.0%0.0%0.0%0.0%0.0%0.0%0.0%

GrowthOperating income

Q3 FY24Q4 FY24Q1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Operating income−$13.5M−$14.0M−$13.1M−$13.0M−$13.2M−$12.8M−$13.1M−$13.4M
YoY growth

Balance sheet, Jun 30, 2026Cash & short-term investments $87.1M · Total debt $2.4M · Total assets $93.4M · Shareholders' equity −$693.0K

Revenue
$1.8M
Operating income
−$13.4M
Net income
−$33.5M
View details

No dividends on record.

Institutions47 holders · as of Mar 31, 202663.40%39.78M shares
Insiders12 holders · as of Sep 2, 20269.34%5.86M shares
Strategic holders3 holders · as of Aug 19, 202612.40%7.78M shares
Otherremainder14.86%9.32M shares

62.75M company shares as of Sep 3, 2026 · institutions as of Mar 31, 2026 · holders as of their latest filing

Two share counts disagree (62.75M in the company's Sep 3, 2026 report, 21.24M elsewhere); stakes use the report.

Top shareholders13F · 13D/G · Form 4

HolderStakeSharesEvidence
Janus Henderson Group PLCInstitution
10.05%6.31M13Fas of Mar 31, 2026
5Am Venture Management, LLCInstitution
9.35%5.87M13Fas of Mar 31, 2026
FMR LLCInstitution
7.86%4.93M13Fas of Mar 31, 2026
Coastlands Capital LPInstitution
7.79%4.89M13Gfiled Dec 11, 2025
Vivo Capital, LLCInstitution
6.77%4.25M13Fas of Mar 31, 2026
See all 25

13F — a manager's quarterly holdings · 13D/13G — an ownership statement filed at 5% or more

Insider tradesForm 4

DateInsiderRoleSharesAvg price
Aug 31, 2026Kelly Goldofficer: Chief Financial Officer+10,000$3.96
Aug 27, 2026Andrew J. Schwabdirector−400,000$4.04
Aug 24, 2026Andrew J. Schwabdirector−10$4.50
Aug 21, 2026Andrew J. Schwabdirector−32,018$4.50
Aug 20, 2026Andrew J. Schwabdirector−114,700$4.54
View details

  • Stoke Therapeutics

    Direct SYNGAP1 ASO rival built on a protein-upregulation platform.

  • Acadia Pharmaceuticals

    Co-developer of a competing SYNGAP1 ASO with rare-disease commercial reach.

  • Biogen

    Intrathecal ASOs that increase protein output in pediatric genetic CNS disease.

  • Wave Life Sciences

    RNA-editing and splicing therapies that restore protein in genetic disease.

ComparePre-market

CompanyPriceChange
CAMP4 Therapeutics$3.83+0.79%$80.7M19.1+18.8%
Stoke Therapeutics$30.70+0.52%$1.97B71.3−32.5%
Acadia Pharmaceuticals$28.93−0.03%$4.95B13.032.54.4+16.4%
Biogen$222.65−0.03%$32.90B39.416.83.3+3.4%
Wave Life Sciences$4.80−1.44%$961.6M14.7−73.9%
Median26.224.79.5−14.5%