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Calidi Biotherapeutics

Develops systemic oncolytic-virus platforms that deliver therapeutic payloads into tumors.

$1.32
After-hours close+0.01 (+0.76%)
At close$1.31(+0.77%)
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Profile

Calidi Biotherapeutics, Inc.CLDIHealth Care

Develops investigational oncolytic-virus platforms for cancer, led by RedTail, which is designed to circulate to metastatic sites, replicate selectively in tumor cells, and produce therapeutic payloads locally.

Develops RedTail, an extracellular-enveloped vaccinia-virus platform designed for systemic delivery to metastatic solid tumors. Its lead candidate is intended to replicate selectively in tumor cells and express an immune-stimulating payload in the tumor microenvironment; other RedTail programs explore in-situ T-cell engagers. NeuroNova and SuperNova are legacy platforms that use stem-cell carriers for high-grade glioma and intratumoral solid tumors.

Operates from San Diego, with research, process-development, and assay work supplemented by academic partners, CROs, and CDMOs in the United States, Germany, and Australia. Every candidate remains investigational, and evidence for RedTail’s systemic delivery and payload expression remains preclinical. Owns no commercial manufacturing facility and has no long-term supply arrangements with outside manufacturers.

Company facts

CEOEric Poma, Ph.D.
ListedSep 13, 2023
ExchangeAMEX
HeadquartersSan Diego, CA
CountryUnited States
Employees29
CIK0001855485
ISINUS3207035078

Key statistics

Market cap$607.8K
EPS (ttm)−$54.14
P/E (ttm)−0.0244
ROE-372.9%
P/B0.5966
P/S0.00
Dividend yield
Beta2.30vs XLV 0.56

Year to date −93.1% · Average volume (30d) 437.4K

Analysts

Price target, next 12 months$5.50+316.7%Median of 2 analysts · vs the Aug 28 close
ConsensusBuy2 of 2 analysts rate it buy or better

Ratings

Target range

Latest analyst notes

No analyst notes in the last 24 months.

Earnings

EPS

Estimate
ReportedDue Nov 17, 2026

Revenue

Estimate
ReportedDue Nov 17, 2026

History

Report dateEPS estEPSSurpriseRevenue estRevenueSurpriseNext session
Aug 13, 2026Q2 FY26−$2.94+3.25%
Mar 30, 2026Q4 FY25−$0.43−0.26%
Mar 27, 2026Q4 FY25−$1.56−$0.57+63.5%−11.55%
Nov 11, 2025Q3 FY25−$1.68−$2.21−31.5%+4.14%
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Financial highlights

11 quartersQ1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Revenue$0$0$0$0$0$0
Gross profit$0$0$0$0−$426.0K$0
Operating income−$5.1M−$5.7M−$5.0M−$4.5M−$4.2M−$4.2M
Net income−$5.0M−$5.7M−$5.1M−$4.1M−$4.1M−$4.2M
Diluted EPS−$35.36−$31.84−$35.36−$8.96−$6.88−$2.94
Gross margin
Operating margin

Fiscal years (4-quarter sums)FY24 $0 · FY25 $0

Balance sheet, Jun 30, 2026Cash & short-term investments $4.1M · Total debt $1.3M · Total assets $7.2M · Shareholders' equity $3.1M

Dividends

No dividends on record.

Ownership

Institutions 27.27%Insiders

Shares outstanding 460.4K · Float 343.8K · 74.7% free float

Insider tradesForm 4

No open-market trades in the last 12 months.

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Peers

  • Genelux

    Systemic vaccinia rival in metastatic lung and other solid tumors.

  • Oncolytics Biotech

    Intravenous oncolytic-virus rival across metastatic solid tumors.

  • Replimune Group

    Armed HSV rival in oncolytic-immunotherapy combinations.

  • Candel Therapeutics

    Locally delivered viral-gene-therapy rival in solid tumors.

CompareAfter-hours close

CompanyPriceChange
Calidi Biotherapeutics$1.32+0.76%$607.8K
Genelux$2.66−0.31%$119.3M14,909.4−98.2%
Oncolytics Biotech$0.8526−0.79%$86.0M
Replimune Group$15.45−0.39%$1.30B
Candel Therapeutics$13.07+0.08%$957.6M
Median14,909.4−98.2%