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Delisting risk

COCP · NASDAQ · Biotechnology

Cocrystal Pharma (COCP)

Develops structure-designed antivirals for influenza, norovirus, and coronavirus infections.

$1.16

At close+0.04 (+3.57%)

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Breakdown13F · 13D/G · Form 4

Institutions25 holders · as of Mar 31, 2026	4.03%	776.2K shares
Insiders8 holders · as of Aug 7, 2026	36.46%	7.02M shares
Strategic holders1 holder · as of Aug 7, 2026	29.55%	5.69M shares
Otherremainder	29.96%	5.77M shares

19.26M company shares as of Sep 3, 2026 · institutions as of Mar 31, 2026 · holders as of their latest filing

Two share counts disagree (19.26M in the company's Sep 3, 2026 report, 13.79M elsewhere); stakes use the report.

Top shareholders13F · 13D/G · Form 4

Holder	Stake	Shares	Evidence
Opko Health, Inc.Strategic	29.55%	5.69M	13Dfiled Aug 7, 2026 ↗
Phillip Md Et Al Frost¹Insiderdirector, 10 percent owner	14.46%	2.78M	13Dfiled Aug 7, 2026 ↗
Steven D. RubinInsiderdirector	13.81%	2.66M	Form 4filed Oct 11, 2024 ↗
Fred HassanInsiderdirector	7.18%	1.38M	Form 4filed Oct 30, 2025 ↗
Vanguard Capital Management LLCInstitution	1.25%	239,971	13Fas of Mar 31, 2026
Renaissance Technologies LLCInstitution	0.64%	123,928	13Fas of Mar 31, 2026
Geode Capital Management, LLCInstitution	0.47%	90,231	13Fas of Mar 31, 2026
Sam LeeInsiderofficer: President and Co-CEO	0.40%	76,355	Form 4filed Oct 11, 2024 ↗
BlackRock, Inc.Institution	0.38%	73,746	13Fas of Mar 31, 2026
T3 Companies, LLCInstitution	0.27%	51,500	13Fas of Mar 31, 2026
James Joseph MartinInsiderofficer: Co-CEO and CFO	0.23%	44,167	Form 4filed Oct 30, 2025 ↗
XTX Topco LtdInstitution	0.19%	36,031	13Fas of Mar 31, 2026
Neuberger Berman Group LLCInstitution	0.17%	31,886	13Fas of Mar 31, 2026
Richard C. Jr PfennigerInsiderdirector	0.16%	31,400	Form 4filed Oct 30, 2025 ↗
Roger D. KornbergInsiderdirector	0.15%	28,109	Form 4filed Oct 11, 2024 ↗
Vanguard Fiduciary Trust CoInstitution	0.12%	24,016	13Fas of Mar 31, 2026
State Street CorpInstitution	0.11%	20,543	13Fas of Mar 31, 2026
Two Sigma Securities, LLCInstitution	0.08%	15,255	13Fas of Mar 31, 2026
Anthony J. JapourInsiderdirector	0.08%	14,924	Form 4filed Oct 11, 2024 ↗
Virtu Financial LLCInstitution	0.07%	13,080	13Fas of Mar 31, 2026
Jane Street Group, LLCInstitution	0.07%	12,711	13Fas of Mar 31, 2026
Parallel Advisors, LLCInstitution	0.07%	12,569	13Fas of Mar 31, 2026
Northern Trust CorpInstitution	0.06%	11,921	13Fas of Mar 31, 2026
Wells Fargo & Company/MNInstitution	0.04%	7,039	13Fas of Mar 31, 2026
UBS Group AGInstitution	0.02%	4,644	13Fas of Mar 31, 2026

Phillip Md Et Al Frost's transaction reports restate only vehicles that traded; the 2026 ownership statement (2.78M) is used instead.

13F — a manager's quarterly holdings · 13D/13G — an ownership statement filed at 5% or more · Form 4 — an insider's transaction report

Institutions13F, as of Mar 31, 2026

25 holders · 776.2K shares · 4 new positions · 10 increased · 4 reduced · 5 closed

Holder	Shares	% outstanding	Chg q/q	Filed
Vanguard Capital Management LLC	240.0K	1.25%	+240.0Knew	May 15, 2026
Renaissance Technologies LLC	123.9K	0.64%	−2.1K	May 14, 2026
Geode Capital Management, LLC	90.2K	0.47%	+7.7K	May 15, 2026
BlackRock, Inc.	73.7K	0.38%	0	May 13, 2026
T3 Companies, LLC	51.5K	0.27%	−800	May 7, 2026
XTX Topco Ltd	36.0K	0.19%	+20.9K	May 15, 2026
Neuberger Berman Group LLC	31.9K	0.17%	0	May 14, 2026
Vanguard Fiduciary Trust Co	24.0K	0.12%	+24.0Knew	May 8, 2026

Ownership statements13D/G · 5% or more, as filed

Holder	% of class	Shares	Form	Filed
Opko Health, Inc.incl. Frost Phillip MD et al, Frost Gamma Investments Trust +1 more	29.60%	5.69M	13D	Aug 7, 2026 ↗
Phillip Frost, M.D.incl. Frost Gamma Investments Trust	13.90%	2.78M	13D	Aug 7, 2026 ↗

Insider tradesForm 4

Latest trades

Date	Insider	Type	Shares	Avg price	Owned after
Aug 5, 2026	Phillip Md Et Al Frostdirector, 10 percent owner:	Purchase	10,000	$0.9816	1,993,551
Aug 3, 2026	Phillip Md Et Al Frostdirector, 10 percent owner:	Purchase	75,000	$0.9412	1,983,551
Feb 24, 2026	Phillip Md Et Al Frostdirector, 10 percent owner:	Purchase	20,000	$0.9976	1,908,551
Feb 6, 2026	Phillip Md Et Al Frostdirector, 10 percent owner:	Purchase	50,000	$0.9456	1,888,551
Dec 31, 2025	Phillip Md Et Al Frostdirector, 10 percent owner:	Purchase	50,000	$0.9455	1,838,551
Dec 30, 2025	Phillip Md Et Al Frostdirector, 10 percent owner:	Purchase	20,000	$0.9655	1,788,551
Dec 24, 2025	Phillip Md Et Al Frostdirector, 10 percent owner:	Purchase	25,000	$0.9703	1,728,551
Dec 26, 2025	Phillip Md Et Al Frostdirector, 10 percent owner:	Purchase	40,000	$0.9736	1,768,551
Nov 26, 2025	Phillip Md Et Al Frostdirector, 10 percent owner:	Purchase · 2 lots	4,000	$0.9938	1,703,551
Nov 25, 2025	Phillip Md Et Al Frostdirector, 10 percent owner:	Purchase	20,000	$0.9406	1,699,551

CongressHouse and Senate disclosures

Not reported.