CRVO · NASDAQ · Biotechnology

CervoMed

Develops neflamapimod for age-related brain disorders.

$2.56
After-hours close−0.04 (−1.54%)
At close$2.60(−1.52%)
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Profile

CervoMed Inc.CRVOHealth Care

Develops neflamapimod, an investigational oral small molecule, for dementia with Lewy bodies and other age-related brain disorders. The clinical-stage business is organized around this single lead candidate, including manufacturing work intended to improve drug concentrations.

Develops neflamapimod, an investigational oral small molecule designed to cross the blood–brain barrier and selectively inhibit p38α. Its clinical programs span dementia with Lewy bodies, non-fluent variant primary progressive aphasia, recovery after ischemic stroke, and amyotrophic lateral sclerosis.

Operations are concentrated in the United States, with a small internal team supported by outside consultants and contractors. The company’s work centers on advancing a single lead candidate through clinical development rather than selling commercial products.

RewinD-LB’s randomized phase did not show significant differences on its primary or secondary outcomes. Subsequent exploratory work examined a newer drug batch after the company identified a drug-substance property and implemented a manufacturing improvement. Clinical results remain investigational rather than regulatory evidence of safety or efficacy.

Company facts

CEOJohn Alam, M.D.
ListedAug 17, 2023
ExchangeNASDAQ
HeadquartersBoston, MA
CountryUnited States
Employees15
CIK0001053691
ISINUS15713L1098

Key statistics

Market cap$24.1M
EPS (ttm)−$3.21
P/E (ttm)−0.8100
ROE-156.0%
P/B1.16
P/S74.63
Dividend yield
Beta1.84vs XLV 0.59

Year to date −66.6% · Average volume (30d) 336.3K

Analysts

Price target, next 12 months$7.00+169.2%Median of 7 analysts · vs the Aug 28 close
ConsensusBuy7 of 7 analysts rate it buy or better

Ratings

Target range

Latest analyst notes

DateFirmActionPrior ratingRatingPrior targetTarget
Aug 20, 2026Roth CapitalTarget$9$7
May 18, 2026Roth CapitalTarget$20$9
Nov 5, 2025H.C. WainwrightTarget$25
Nov 5, 2025HC Wainwright & Co.UpgradeNeutralBuy
Oct 17, 2025Roth CapitalTarget$16$20

Earnings

EPS

Estimate−$0.61
ReportedDue Nov 12, 2026

Revenue

Estimate$50.0K
ReportedDue Nov 12, 2026

History

Report dateEPS estEPSSurpriseRevenue estRevenueSurpriseNext session
Aug 10, 2026Q2 FY26−$0.80−$0.64+19.7%$50.0K−0.35%
Aug 7, 2026Q2 FY26−$0.87−$0.64+26.4%$50.0K+3.99%
May 18, 2026Q1 FY26−$0.90−$0.86+4.4%$71.4K−4.93%
Mar 13, 2026Q4 FY25−$0.79−$0.88−11.4%$90.8K$6.5K−92.8%+1.41%
View details

Financial highlights

12 quartersQ1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Revenue$0$0$322.6K$0$0$0
Gross profit$0$0$322.6K$0$0$0
Operating income−$5.3M−$6.6M−$8.0M−$8.3M−$8.1M−$6.7M
Net income−$4.9M−$6.3M−$7.7M−$8.1M−$8.0M−$6.6M
Diluted EPS−$0.56−$0.70−$0.84−$0.87−$0.86−$0.64
Gross margin100.0%
Operating margin-2,493.8%

Fiscal years (4-quarter sums)FY21 $0 · FY22 $0 · FY23 $0 · FY24 $0 · FY25 $322.6K

Balance sheet, Jun 30, 2026Cash & short-term investments $24.9M · Total debt $0 · Total assets $26.0M · Shareholders' equity $23.0M

Dividends

No dividends on record.

Ownership

Institutions 19.11%1.77M sharesInsiders 52.02%4.82M sharesOther 28.87%2.67M shares

Shares outstanding 9.26M · Float

Float — provider float is below the insider stake.

The provider's float is smaller than the insider stake it should exclude, so it is not shown.

Top shareholders13F · 13D/G · Form 4

HolderShares% outstandingFormFiled
Joshua S. Boger · director, 10 percent owner: 1.80M19.40%Form 4Jun 15, 2026
Armistice Capital, LLC1.59M9.53%13GAug 14, 2026
John J. Alam · director, 10 percent owner, officer: CEO & President1.50M16.16%Form 4Nov 19, 2025
Sylvie Gregoire · director, 10 percent owner: 1.50M16.16%Form 4Nov 19, 2025
RA Capital Management, L.P.1.03M9.90%13GAug 20, 2025

Insider tradesForm 4

DateInsiderRoleSharesAvg price
Jun 11, 2026Joshua S. Bogerdirector, 10 percent owner: +2,866,242$3.20
Nov 17, 2025John J. Alamdirector, 10 percent owner, officer: CEO & President+21,600$8.46
Nov 17, 2025William Robert Elderofficer: CFO, GC & Secretary+1,000$8.45
Nov 18, 2025William Robert Elderofficer: CFO, GC & Secretary+2,500$8.32
Nov 17, 2025Sylvie Gregoiredirector, 10 percent owner: +21,600$8.46
View details

Peers

CompareAfter-hours close

CompanyPriceChange
CervoMed$2.56−1.54%$24.1M74.6−99.7%
Cognition Therapeutics$1.04+1.99%$91.3M
Coya Therapeutics$4.57−0.52%$107.7M13.4+35.6%
Ionis Pharmaceuticals$61.05+0.02%$10.15B11.6−40.7%
Median12.5−2.6%