CTNM · NASDAQ · Biotechnology

Contineum Therapeutics (CTNM)

Discovers and develops oral small-molecule therapies for neuroscience, inflammation and immunology.

$17.24
At close+0.69 (+4.14%)
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Contineum Therapeutics, Inc. Class A Common StockCTNMHealth Care

Develops oral small-molecule therapies for neuroscience, inflammation and immunology indications. Its clinical and discovery portfolio includes PIPE-791, PIPE-307 and CTX-343, with PIPE-307 subject to a global license arrangement with Janssen.

Discovers and develops oral small-molecule therapies for neuroscience, inflammation and immunology indications. The portfolio comprises clinical candidates PIPE-791, PIPE-307 and CTX-343, alongside discovery programs, within a single reportable segment.

Operations are concentrated in San Diego, while the company pursues programs for patients globally. PIPE-307 is covered by an exclusive worldwide license to Janssen; Contineum retained the right to advance it in a Phase 2 trial for relapsing-remitting multiple sclerosis.

The VISTA trial did not meet its prespecified efficacy endpoints, and Janssen has sole discretion over further PIPE-307 development for relapsing-remitting multiple sclerosis.

Company facts

CEOCarmine Stengone
ListedApr 5, 2024
ExchangeNASDAQ
HeadquartersSan Diego, CA
CountryUnited States
Employees51
CIK0001855175
ISINUS21217B1008

Market cap$648.6M
EPS (ttm)−$1.73
P/E (ttm)−9.97
ROE-24.7%
P/B2.70
P/S0.00
Dividend yieldDiv yield
Beta1.22vs XLV 0.02

Price target$16.00−7.2%Avg of 3 analysts
ConsensusBuy2 of 3 analysts
Ratings

Target rangeAs of Sep 2, 2026

Latest analyst notes

DateFirmActionPrior ratingRatingPrior targetTarget
May 14, 2026Morgan StanleyReiterateEqual Weight$14$16
Jan 8, 2026Morgan StanleyDowngradeOverweightEqual Weight$14
Nov 24, 2025Robert W. BairdTarget$16$14
Nov 21, 2025RBC CapitalReiterateOutperform$30$22
Sep 25, 2025Leerink PartnersTarget$20

Next report
Oct 29, 2026
estimated · in 56 days
EPS estimate
−$0.45
Revenue estimate
$5.7M
Fiscal quarter
Q3 FY26

EPSReportedEstimate

Mar '25May '25Aug '25Oct '25Mar '26May '26Jul '26Oct '26
Reported−$0.56−$0.62−$0.62−$0.45−$0.49−$0.39−$0.40Pending
Estimate−$0.44−$0.56−$0.56−$0.58−$0.50−$0.55−$0.45−$0.45
Surprise−27.3%−10.7%−10.7%+22.4%+2.0%+29.1%+10.9%

RevenueReportedEstimate

Mar '25May '25Aug '25Oct '25Mar '26May '26Jul '26Oct '26
ReportedPending
Estimate$6.0M$7.5M$5.0M$7.5M$5.7M
Surprise
Estimate−$0.45
ReportedDue Oct 29, 2026
Estimate$5.7M
ReportedDue Oct 29, 2026
View details

Debt to equity2.70%
Current ratio3,717.10%

ProfitabilityRevenueNet incomeNet margin

Q3 FY24Q4 FY24Q1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Revenue$0$0$0$0$0$0$0$0
Net income−$10.3M−$14.6M−$16.0M−$16.0M−$12.8M−$15.2M−$14.5M−$15.2M
Net margin

GrowthOperating income

Q3 FY24Q4 FY24Q1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Operating income−$13.0M$84.7M−$18.1M−$17.9M−$14.9M−$17.1M−$16.9M−$17.4M
YoY growth−120.2%

Balance sheet, Jun 30, 2026Cash & short-term investments $236.6M · Total debt $6.6M · Total assets $250.4M · Shareholders' equity $239.7M

Revenue
$0
Operating income
−$17.4M
Net income
−$15.2M
View details

No dividends on record.

Institutions91 holders · as of Mar 31, 202681.22%30.56M shares
Insiders3 holders · as of Aug 3, 20260.44%166.0K shares
Otherremainder18.34%6.90M shares

37.62M company shares as of Sep 3, 2026 · institutions as of Mar 31, 2026 · holders as of their latest filing

This company has 2 share classes; every stake here is a share of the whole company.

Top shareholders13F · 13D/G · Form 4

HolderStakeSharesEvidence
Suvretta Capital Management, LLCInstitution
7.55%2.84M A13Fas of Mar 31, 2026
Janus Henderson Group PLCInstitution
7.27%2.73M A13Fas of Mar 31, 2026
Johnson & JohnsonInstitution
5.26%1.98M A13Fas of Mar 31, 2026
Franklin Resources IncInstitution
4.89%1.84M A13Fas of Mar 31, 2026
Balyasny Asset Management L.P.Institution
4.48%1.69M A13Fas of Mar 31, 2026
See all 25

13F — a manager's quarterly holdings

Insider tradesForm 4

DateInsiderRoleSharesAvg price
Aug 3, 2026Carmine N. Stengonedirector, officer: CEO and President−2,500$16.01
Jul 9, 2026Daniel S. Lorrainofficer: Chief Scientific Officer−25$16.00
Jul 8, 2026Carmine N. Stengonedirector, officer: CEO and President−2,500$16.00
Jul 1, 2026Daniel S. Lorrainofficer: Chief Scientific Officer−8,353$15.84
Jun 30, 2026Daniel S. Lorrainofficer: Chief Scientific Officer−28,826$16.04
View details

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