DSGN · NASDAQ · Biotechnology

Design Therapeutics

Develops GeneTAC small molecules that tune disease-causing gene expression.

$15.11
After-hours close+0.01 (+0.07%)
At close$15.10(−0.98%)

Breakdown13F · Form 4

Institutions 69.78%43.58M sharesInsiders 1.60%1.00M sharesOther 28.62%17.88M shares

Shares outstanding 62.46M · Float 32.94M · 52.7% free float

Top shareholders13F · 13D/G · Form 4

HolderShares% outstandingFormFiled
Simeon George6.61M10.70%13DMar 11, 2026
Sr One Capital Management, LP6.53M10.45%13FAug 12, 2026
Sirenia Capital Management LP5.96M9.50%13GAug 14, 2026
Light Irrevocable Trust #1 dated April 22, 20193.83M6.90%13GFeb 7, 2025
Star Irrevocable Trust #1 dated April 22, 20193.83M6.90%13GFeb 7, 2025

Institutions13F, as of Jun 30, 2026

141 holders · 43.58M shares · 31 new positions · 93 increased · 31 reduced · 17 closed

HolderShares% outstandingChg q/qFiled
Sr One Capital Management, LP6.53M10.45%0Aug 12, 2026
Logos Global Management LP3.00M4.80%+1.05MAug 14, 2026
Baker Bros. Advisors LP2.68M4.29%+92.5KAug 14, 2026
Driehaus Capital Management LLC2.66M4.26%+916.1KAug 14, 2026
BlackRock, Inc.2.66M4.26%+526.3KAug 7, 2026
Point72 Asset Management, L.P.2.37M3.79%−356.3KAug 14, 2026
Trails Edge Capital Partners, LP2.00M3.20%+1.15MAug 14, 2026
Frazier Life Sciences Management, L.P.1.81M2.90%+1.81MAug 14, 2026

Beneficial owners13D/G · 5% or more, as filed

Holder% of classSharesFormFiled
Simeon Georgeincl. SR One Capital Partners I, LP, SR One Capital Fund I Aggregator, LP +1 more10.70%6.61M13DMar 11, 2026
Sirenia Capital Management LP9.50%5.96M13GAug 14, 2026
Light Irrevocable Trust #1 dated April 22, 20196.90%3.83M13GFeb 7, 2025
Star Irrevocable Trust #1 dated April 22, 20196.90%3.83M13GFeb 7, 2025
Point72 Asset Management, L.P.5.10%3.20M13GJun 9, 2026

InsidersForm 4

InsiderRoleShares% outstandingFiled
Arsani Williamdirector1.00M1.60%Aug 14, 2025

5 ten-percent owners hold 24.14M shares by Form 4, outside the officers-and-directors figure above · 13 people have not refiled in the last 18 months (17.58M shares), so they are not in the figure above

Latest trades

No open-market trades in the last 12 months.

CongressHouse and Senate disclosures

Not reported.