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PCEliquiditysentimentbreakoutsdowngradesP/E 28.4threadsAAPLSPXvolatilityNDXflowscyclesliquidityestimatesEPS 4.12

Delisting risk

ENSC · NASDAQ · Biotechnology

Ensysce Biosciences

Develops opioid-safety prodrugs and a neuroplastogenic pain candidate.

$0.3999

Pre-market+0.01 (+1.86%)

At close$0.3926(−1.83%)

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Breakdown13F · 13D/G · Form 4

	Insiders2 holders · as of Aug 18, 2026	6.21%	1.21M shares
	Otherremainder	93.79%	18.25M shares

19.46M company shares as of Sep 1, 2026 · holders as of their latest filing

Two share counts disagree (19.46M in the company's Sep 1, 2026 report, 15.37M elsewhere); stakes use the report.

Top shareholders13F · 13D/G · Form 4

Holder	Stake	Shares	Evidence
Bob G. Gower¹Insiderdirector	6.20%	1.21M	13Dfiled Aug 18, 2026 ↗
William H. Chang²Insiderdirector, 10 percent owner	0.00%	721	13Dfiled Jul 12, 2021 ↗
AQR Capital Management, LLCInstitution	—2.20% of class, as filed	—	13D/Gfiled Feb 15, 2019 ↗
BMO Capital Markets Corp.Institution	—6.23% of class, as filed	—	13Gfiled Feb 14, 2020 ↗
CVI Investments, Inc.Strategic	—7.80% of class, as filed	—	13Gfiled Dec 16, 2022 ↗
Davidson Kempner Capital Management LPInstitution	—5.83% of class, as filed	—	13Gfiled Dec 11, 2017 ↗
LLCStrategic	—4.50% of class, as filed	—	13Gfiled Feb 13, 2018 ↗
Matthews Lane Capital Partners LLCStrategic	—18.10% of class, as filed	—	13Gfiled Feb 10, 2021 ↗
Rockledge Capital CorporationStrategic	—9.99% of class, as filed	—	13Gfiled Feb 7, 2023 ↗
WrightInsider	—5.40% of class, as filed	—	13Dfiled Jul 12, 2021 ↗
HG Vora Capital Management, LLC³Strategic10 percent owner	0.00%	962	Form 4filed Jan 17, 2018 ↗
Lynn Kirkpatrick⁴Insiderofficer: Chief Executive Officer	0.00%	106	Form 4filed May 27, 2022 ↗
A. Lorne Weil³Insiderdirector, officer: Executive Chairman	0.00%	74	Form 4filed Jan 17, 2018 ↗
George Peng³Insiderofficer: Chief Financial Officer	0.00%	24	Form 4filed Jan 17, 2018 ↗
Eric Carrera³Insiderofficer: Senior Vice President	0.00%	15	Form 4filed Jan 17, 2018 ↗
David Carl Humphrey⁵Insiderofficer: Chief Financial Officer	0.00%	14	Form 4filed Jul 2, 2021 ↗
Marc J. Falcone⁶Insiderdirector	0.00%	7	Form 4filed Dec 1, 2017 ↗
Steven M. Rittvo⁶Insiderdirector	0.00%	7	Form 4filed Dec 1, 2017 ↗
David L. Weinstein⁶Insiderdirector	0.00%	7	Form 4filed Dec 1, 2017 ↗
Stanley Morgan⁷Insider10 percent owner	0.00%	0	Form 4filed Jun 23, 2020 ↗
Daniel B. Silvers^3,8Insiderdirector, officer: Chief Executive Officer	0.00%	0	Form 4filed Jan 17, 2018 ↗

Bob G. Gower's transaction reports restate only vehicles that traded; the 2026 ownership statement (1.21M) is used instead.
William H. Chang's transaction reports restate only vehicles that traded; the 2021 ownership statement (721) is used instead.
Last filed Jan 17, 2018; leaving the company requires no filing. Not in the bar.
Last filed May 27, 2022; leaving the company requires no filing. Not in the bar.
Last filed Jul 2, 2021; leaving the company requires no filing. Not in the bar.
Last filed Dec 1, 2017; leaving the company requires no filing. Not in the bar.
Last filed Jun 23, 2020; leaving the company requires no filing. Not in the bar.
Daniel B. Silvers reports a block also reported by Matthews Lane Capital Partners LLC; it is counted once, under Matthews Lane Capital Partners LLC.

13D/13G — an ownership statement filed at 5% or more · Form 4 — an insider's transaction report

Institutions13F

No 13F holders on record.

Ownership statements13D/G · 5% or more, as filed

Holder	% of class	Shares	Form	Filed
RA Capital Healthcare Fund, L.P.incl. RA Capital Management, L.P., Peter Kolchinsky +1 more	9.90%		13G	Nov 6, 2024 ↗
Perceptive Life Sciences Master Fund, Ltd.incl. Perceptive Advisors LLC, Joseph Edelman	8.70%		13G	Oct 29, 2024 ↗
Tony Mooreincl. Moez Kassam, Anson Management GP LLC +3 more	7.10%		13G	Nov 14, 2024 ↗
Bob Gene Gower	6.10%	1.21M	13D	Aug 18, 2026 ↗

Insider tradesForm 4

Latest trades

Date	Insider	Type	Shares	Avg price	Owned after
Aug 7, 2026	Bob G. Gowerdirector	Purchase	400,000	$0.4950	916,740
Apr 23, 2026	Bob G. Gowerdirector	Purchase	508,614	$0.4840	516,740

CongressHouse and Senate disclosures

Not reported.