ENTX · NASDAQ · Biotechnology

Entera Bio

Develops oral peptide therapies through its N-Tab delivery platform.

$3.03
After-hours close−0.01 (−0.33%)
At close$3.04(−1.30%)
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Profile

Entera Bio Ltd.ENTXHealth Care

Develops oral peptide and protein-replacement therapies using N-Tab, with EB613 its most advanced osteoporosis candidate. Its clinical pipeline also includes EB612 for hypoparathyroidism and EB618 for metabolic syndromes, alongside OPKO collaborations on oral peptide programs.

Develops oral peptide and protein-replacement therapies through N-Tab®, a proprietary delivery platform. EB613, its most advanced candidate, is an oral PTH program for osteoporosis; EB612 targets hypoparathyroidism and EB618 targets metabolic syndromes.

In Jerusalem, the clinical-stage business develops its pipeline and pursues selected development and commercial partnerships. OPKO is its documented external-development partner, with collaborations spanning oral OXM and long-acting PTH programs.

Program progress depends on clinical development and regulatory pathways. The long-acting PTH collaboration gives Entera and OPKO shared ownership and development-cost responsibilities, while the oral OXM program has a different ownership and cost-sharing structure.

Company facts

CEOMiranda Toledano
ListedJun 28, 2018
ExchangeNASDAQ
HeadquartersJerusalem, Israel
CountryIsrael
Employees22
CIK0001638097
ISINIL0011429839

Key statistics

Market cap$149.3M
EPS (ttm)−$0.3467
P/E (ttm)−8.74
ROE-147.2%
P/B21.04
P/S0.00
Dividend yield
Beta0.71vs XLV 0.34

Year to date +71.8% · Average volume (30d) 3.4M

Analysts

No analyst consensus on record.

Earnings

EPS

Estimate−$0.08
ReportedDue Nov 13, 2026

Revenue

Estimate
ReportedDue Nov 13, 2026

History

Report dateEPS estEPSSurpriseRevenue estRevenueSurpriseNext session
Aug 7, 2026Q2 FY26−$0.08−$0.14−75.0%$0+5.92%
May 8, 2026Q1 FY26−$0.08−$0.07+12.5%−10.00%
Mar 27, 2026Q4 FY25−$0.09−$0.07+22.2%−11.50%
Nov 14, 2025Q3 FY25−$0.09−$0.07+22.2%−1.11%
View details

Financial highlights

12 quartersQ1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Revenue$42.0K$0$0$0$0$0
Gross profit$0$0−$8.0K$0−$7.0K$0
Operating income−$2.6M−$2.7M−$3.3M−$3.0M−$3.5M−$4.6M
Net income−$2.6M−$2.7M−$3.2M−$3.0M−$3.5M−$7.3M
Diluted EPS−$0.06−$0.06−$0.07−$0.07−$0.07−$0.14
Gross margin0.0%
Operating margin-6,102.4%

Fiscal years (4-quarter sums)FY21 $571.0K · FY22 $134.0K · FY23 $0 · FY24 $181.0K · FY25 $42.0K

Balance sheet, Jun 30, 2026Cash & short-term investments $11.3M · Total debt $425.0K · Total assets $19.5M · Shareholders' equity $7.3M

Dividends

No dividends on record.

Ownership

Institutions 15.97%7.87M sharesInsiders 4.47%2.20M sharesOther 79.56%39.21M shares

Shares outstanding 49.29M · Float 40.37M · 81.9% free float

Top shareholders13F · 13D/G · Form 4

HolderShares% outstandingFormFiled
TCG Crossover GP III, LLC12.25M7.10%13GAug 4, 2026
Biotechnology Value Fund L P9.17M5.30%13DAug 4, 2026
Knoll Capital Management, LLC5.88M11.93%13FMay 15, 2026
Opko Health, Inc.3.69M8.10%13GApr 2, 2025
Miranda Jayne Toledano · director, officer: Chief Executive Officer774.1K1.57%Form 4Jul 16, 2026

Insider tradesForm 4

DateInsiderRoleSharesAvg price
Mar 9, 2026Geno J. Germanodirector+20,000$1.30
Mar 5, 2026Sean Ellisdirector+10,000$1.23
Feb 9, 2026Sean Ellisdirector+18,000$1.24
Feb 10, 2026Geno J. Germanodirector+20,000$1.49
Feb 10, 2026Haya Taiteldirector+7,500$1.48
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Peers

  • Amgen

    Established osteoporosis medicines with bone-building and antiresorptive options

  • Ascendis Pharma (ADR)

    YORVIPATH PTH replacement for chronic hypoparathyroidism

  • AstraZeneca (ADR)

    Phase III PTH1R agonist program for chronic hypoparathyroidism

  • Septerna

    Next-generation oral PTH1R agonists for hypoparathyroidism

  • Novo Nordisk (ADR)

    Oral GLP-1 obesity medicines and a broad semaglutide franchise

CompareAfter-hours close

CompanyPriceChange
Entera Bio$3.03−0.33%$149.3M
Amgen$430.27−0.49%$233.38B26.918.46.1+9.7%
Ascendis Pharma (ADR)$247.910.00%$15.40B18.731.912.6+108.2%
AstraZeneca (ADR)$161.79−0.55%$252.33B24.415.24.1+6.4%
Septerna$38.91+0.13%$1.75B17.7+22,375.6%
Novo Nordisk (ADR)$45.60+0.00%$202.54B11.218.44.0+0.0%
Median21.618.46.1+9.7%