FTH · NASDAQ · Biotechnology

Faeth Therapeutics

Develops PIKTOR, an oral cancer regimen designed to block multiple PAM-pathway nodes.

$33.84
After-hours close+0.16 (+0.48%)
At close$33.68(−0.18%)
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Profile

Faeth Therapeutics, Inc.FTHHealth Care

Develops PIKTOR, an investigational oral cancer regimen combining serabelisib and sapanisertib, while advancing preclinical NEAAR and IEM programs. With no product revenue or commercial sales organization, its model finances clinical development while relying on licensed rights and external research, trial, and manufacturing partners.

Develops cancer therapeutics around PIKTOR, an investigational oral combination of serabelisib and sapanisertib that targets several points in the PI3K/AKT/mTOR pathway. Its clinical programs study PIKTOR in advanced endometrial cancer and HR-positive/HER2-negative advanced breast cancer; its earlier work includes the preclinical NEAAR and IEM programs. Based in Austin, Texas, it has development rights for PIKTOR components worldwide within licensed fields.

Runs a focused, pre-revenue development model, relying on CROs, clinical sites, consultants, suppliers, and contract manufacturers rather than a commercial sales organization. Progress depends on clinical evidence, regulatory approval, reliable supply of both active ingredients, licensed rights from Takeda and Millennium Takeda, and external execution.

Company facts

CEOAnand Parikh
ListedJun 16, 2026
ExchangeNASDAQ
HeadquartersAustin, TX
CountryUnited States
Employees29
CIK0001829802
ISINUS81728A2078

Key statistics

Market cap$872.4M
EPS (ttm)−$141.65
P/E (ttm)−0.2389
ROE-192.8%
P/B1.10
P/S−179.83
Dividend yield
Beta2.00vs XLV −0.23

Year to date +249% · Average volume (30d) 299.4K

Analysts

Price target, next 12 months$56.50+67.0%Median of 5 analysts · vs the Aug 28 close
ConsensusBuy5 of 5 analysts rate it buy or better

Ratings

Target range

Latest analyst notes

DateFirmActionRatingTarget
Aug 21, 2026NeedhamInitiateBuy$56
Jul 31, 2026Raymond JamesInitiateOutperform$56
Jul 27, 2026OppenheimerInitiateOutperform$60
Jul 20, 2026CitigroupInitiateOutperform
Jun 25, 2026Robert W. BairdTarget$57

Earnings

EPS

Estimate−$0.66
ReportedDue Nov 13, 2026

Revenue

Estimate
ReportedDue Nov 13, 2026

History

Report dateEPS estEPSSurpriseRevenue estRevenueSurpriseNext session
Aug 4, 2026Q2 FY26−$2.64−$2.84−7.6%−6.73%
May 15, 2026Q1 FY26−$0.62−$131.45−21,101.6%−2.55%
Mar 30, 2026Q4 FY25−$4.81−$3.74+22.2%+25.43%
Nov 14, 2025Q3 FY25−$4.11−$3.62+11.9%−$4.9M+1.62%
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Financial highlights

11 quartersQ1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Revenue$0$0−$4.9M$0$0$0
Gross profit$0$0$0$0−$133.0M$0
Operating income−$7.3M−$5.2M−$4.9M−$5.0M−$170.6M−$18.4M
Net income−$6.9M−$4.9M−$4.6M−$4.7M−$170.2M−$16.0M
Diluted EPS−$5.45−$3.91−$3.62−$3.74−$131.45−$2.84
Gross margin
Operating margin

Fiscal years (4-quarter sums)FY24 $0 · FY25 −$4.9M

Balance sheet, Jun 30, 2026Cash & short-term investments $186.4M · Total debt $592.0K · Total assets $189.3M · Shareholders' equity $173.0M

Dividends

No dividends on record.

Ownership

Institutions Insiders

Shares outstanding 25.78M · Float 18.61M

This issuer lists more than one class and the share count spans them all, so a stake here reads as a share of the whole company, not of this class.

Top shareholders13F · 13D/G · Form 4

HolderShares% of companyFormFiled
S2G Investments, LLC2.58M9.99% of class13GJun 23, 2026
Suvretta Capital Management, LLC2.02M7.80% of class13GJun 23, 2026
Khosla Ventures VI, LP1.64M6.40% of class13GAug 14, 2026

Insider tradesForm 4

Nothing filed in the last 12 months.

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Peers

  • Celcuity

    Approved multi-node pathway regimen in advanced HR+/HER2- breast cancer.

  • Novartis (ADR)

    Approved PI3K-alpha and mTOR options in advanced HR+/HER2- breast cancer.

  • AstraZeneca (ADR)

    Approved AKT therapy for biomarker-selected HR+/HER2- breast cancer.

  • Relay Therapeutics

    Phase 3 PI3K-alpha program for PIK3CA-mutant HR+/HER2- breast cancer.

  • Eli Lilly

    Phase 3 PI3K-alpha program for PIK3CA-mutant HR+/HER2- breast cancer.

  • OnKure Therapeutics

    Early PI3K-alpha program in metastatic breast cancer.

CompareAfter-hours close

CompanyPriceChange
Faeth Therapeutics$33.84+0.48%$872.4M
Celcuity$90.10+1.81%$4.31B
Novartis (ADR)$153.810.00%$292.35B23.216.45.3+0.9%
AstraZeneca (ADR)$161.79−0.55%$252.33B24.415.24.1+6.4%
Relay Therapeutics$19.10+1.82%$4.11B397.4−48.3%
Eli Lilly$1,173.00−0.08%$1.10T39.428.713.9+47.7%
OnKure Therapeutics$3.790.00%$153.5M
Median24.416.49.6+3.7%