Jaguar Health (JAGX)
Develops and supplies crofelemer treatments for intestinal failure and diarrhea in people and animals.
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Develops crofelemer for rare intestinal-failure diseases and supplies human and canine diarrhea products through a U.S. licensee. The business combines botanical sourcing, outsourced manufacturing, regulatory development, and licensing, with its pipeline concentrated on one molecule.
Develops crofelemer powder for oral solution as an adjunct to parenteral support in microvillus inclusion disease and short bowel syndrome with intestinal failure. Coordinates botanical sourcing, outsourced manufacturing, regulatory development, and licensing; development activity spans the United States, European Union, and Middle East. Direct product activity includes non-prescription Neonorm digestive-health products, while Gelclair's current commercial status is unresolved in reviewed sources.
Supplies Mytesi for noninfectious diarrhea in adults with HIV/AIDS and Canalevia-CA1 for chemotherapy-induced diarrhea in dogs to Future Pak, the exclusive U.S. commercial licensee. Its business depends on third-party manufacturing, Amazonian plant-latex collection, regulatory acceptance, licensee performance, and clinical progress from a crofelemer-centered pipeline.
Company facts
Target rangeAs of Sep 2, 2026
Latest analyst notes
| Date | Firm | Action | Target |
|---|---|---|---|
| Jun 25, 2026 | BOCOM International Holdings Company | Target | $3.21 |
EPSReportedEstimate
RevenueReportedEstimate
Balance sheet, Jun 30, 2026Cash & short-term investments $6.6M · Total debt $16.7M · Total assets $34.2M · Shareholders' equity $6.6M
- Revenue
- $1.2M
- Operating income
- −$7.6M
- Net income
- −$12.7M
No dividends on record.
| Institutions10 holders · as of Mar 31, 2026 | 0.14% | 7.3K shares | |
| Insiders9 holders · as of Mar 12, 2026 | 0.06% | 3.0K shares | |
| Otherremainder | 99.80% | 5.16M shares |
5.17M company shares as of Sep 3, 2026 · institutions as of Mar 31, 2026 · holders as of their latest filing
Two share counts disagree (5.17M in the company's Sep 3, 2026 report, 66.6K elsewhere); stakes use the report.
Top shareholders13F · 13D/G · Form 4
| Holder | Stake | Shares | Evidence |
|---|---|---|---|
UBS Group AGInstitution | 0.06% | 112,906 | 13Fas of Mar 31, 2026 |
Geode Capital Management, LLCInstitution | 0.06% | 110,129 | 13Fas of Mar 31, 2026 |
Lisa A. ConteInsiderdirector, officer: See Remarks | 0.02% | 836 | Form 4filed Jan 21, 2026 ↗ |
HRT Financial LPInstitution | 0.01% | 15,187 | 13Fas of Mar 31, 2026 |
Two Sigma Securities, LLCInstitution | 0.01% | 12,551 | 13Fas of Mar 31, 2026 |
| See all 25 → | |||
13F — a manager's quarterly holdings · Form 4 — an insider's transaction report
Insider tradesForm 4
No open-market trades in the last 12 months.
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Compare
| Company | Price | Change | |||||
|---|---|---|---|---|---|---|---|
| Jaguar Health | $0.7398 | +1.20% | $48.6K | — | — | 0.0 | −58.9% |
| Takeda (ADR) | $18.73 | +1.55% | $58.65B | 51.2 | 56.8 | 2.0 | +5.8% |
| Ironwood Pharmaceuticals | $4.49 | +1.81% | $725.9M | 5.7 | 3.8 | 1.9 | +32.6% |
| Median | 28.5 | 30.3 | 1.9 | +19.2% |