LKFT · NASDAQ · Biotechnology

Lakefront Biotherapeutics (LKFT)

Develops and acquires autoimmune T-cell engager medicines with Gilead.

$28.96
Pre-market+0.14 (+0.50%)
At close$28.82(+0.93%)
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Lakefront Biotherapeutics N.V.LKFTHealth Care

Develops acquired autoimmune T-cell engagers, led by gamgertamig, while partnering with Gilead on later development and commercialization. Its model combines selective asset transactions with early clinical execution rather than product sales.

Builds a development-stage biotechnology pipeline by acquiring or licensing clinically de-risked medicines and advancing selected early clinical studies. The core program, gamgertamig, is a subcutaneous BCMAxCD3 T-cell engager being studied in autoimmune cytopenias and seropositive autoimmune diseases; a selective TYK2 small-molecule program is under strategic review. Residual economics include royalties, earn-outs, and transitional supply from the transferred Jyseleca business.

Executes asset transactions and early development while using Gilead for registrational studies and commercialization of gamgertamig outside Keymed's Greater China territories. The model depends on clinical progress, external trial and supply partners, and Gilead's collaboration and opt-in rights; no approved proprietary product remains in the current development portfolio.

Company facts

CEOHenry Gosebruch
ListedMay 14, 2015
ExchangeNASDAQ
HeadquartersMechelen, Belgium
CountryBelgium
Employees452
CIK0001421876
ISINUS36315X1019

Market cap$1.90B
EPS (ttm)$10.50
P/E (ttm)2.74
ROE19.6%
P/B0.5626
P/S1.65
Dividend yieldDiv yield
Beta0.57vs XLV 0.53

Price target$26.00−9.8%Avg of 2 analysts
ConsensusHold2 of 2 analysts
Ratings

Target rangeAs of Sep 2, 2026

Latest analyst notes

DateFirmActionRatingPrior targetTarget
Aug 11, 2026Morgan StanleyReiterateEqual Weight$30$26
Jul 10, 2026Morgan StanleyTarget$30

Next report
Nov 12, 2026
in 70 days
EPS estimate
−$0.82
Revenue estimate
$9.0M
Fiscal quarter
Q3 FY26

EPSReportedEstimate

Feb '25Apr '25Jul '25Nov '25Feb '26May '26Aug '26Nov '26
Reported$0.30−$2.67−$1.85−$3.54$13.90$0.25$0.03Pending
Estimate−$0.55−$0.14−$0.23−$0.48−$0.13−$0.94−$0.15−$0.82
Surprise+155.1%−1,783.0%−711.8%−641.4%+11,077.7%+126.2%+123.1%

RevenueReportedEstimate

Feb '25Apr '25Jul '25Nov '25Feb '26May '26Aug '26Nov '26
Reported$79.3M$85.3M$76.8M$82.1M$1.05B$7.6M$14.0MPending
Estimate$77.0M$71.9M$80.1M$76.1M$82.9M$9.6M$14.0M$9.0M
Surprise+3.0%+18.6%−4.1%+7.9%+1,166.2%−20.4%+0.3%
Estimate−$0.82
ReportedDue Nov 12, 2026
Estimate$9.0M
ReportedDue Nov 12, 2026
View details

Debt to equity0.20%
Current ratio3,282.50%

ProfitabilityRevenueNet incomeNet margin

Q3 FY24Q4 FY24Q1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Revenue$69.5M$87.7M$87.1M$75.8M$82.6M$1.05B$7.5M$14.1M
Net income−$58.6M$29.4M−$178.1M−$122.8M−$234.7M$908.2M$16.8M$2.4M
Net margin0.0%33.5%0.0%0.0%0.0%86.8%223.6%17.4%

GrowthOperating income

Q3 FY24Q4 FY24Q1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Operating income−$63.1M−$94.1M−$184.3M−$66.2M−$48.4M$881.1M−$74.0M−$50.5M
YoY growth

Balance sheet, Jun 30, 2026Cash & short-term investments $2.60B · Total debt $7.4M · Total assets $3.89B · Shareholders' equity $3.78B

Revenue
$14.1M
Operating income
−$50.5M
Net income
$2.4M

Reported in EUR, converted at the latest exchange rate

View details

No dividends on record.

No ownership filings on record for this listing.

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ComparePre-market

CompanyPriceChange
Lakefront Biotherapeutics$28.96+0.50%$1.90B2.71.7−81.7%
Cullinan Therapeutics$22.16−0.89%$1.37B
Cabaletta Bio$3.60+0.71%$582.1M