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LSTA · NASDAQ · Biotechnology

Lisata Therapeutics (LSTA)

Develops certepetide for tumor-penetrating cancer therapy combinations.

$1.57
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Lisata Therapeutics, Inc.LSTAHealth Care

Develops certepetide, an investigational peptide intended to improve delivery of co-administered or tethered therapies into solid tumors. Operates as a single clinical-stage segment, relying on partners and investigator-led trials while potential economics depend on licensing, milestones, royalties, and commercialization.

Develops certepetide, a cyclic peptide being studied with other therapies to help them penetrate solid tumors through the CendR uptake pathway and modify the tumor microenvironment. The pipeline centers on clinical studies in pancreatic and biliary cancers, including investigator-led work in the United States, Australia, New Zealand, Estonia, Latvia, and Lithuania, plus partner-led development in Greater China. The company has no approved products or recurring product sales.

Operates as a single clinical-stage segment, pairing company-sponsored development with investigator trials, territorial licenses, and technology collaborations. Potential economics depend on licensing payments, development and regulatory milestones, royalties, and eventual commercial arrangements; academic sponsors, collaborators, and third parties undertake material clinical and manufacturing work. The portfolio, collaborations, and platform narrative are concentrated on certepetide, while a pending cash tender offer could replace the standalone strategy.

Company facts

CEODavid J. Mazzo, Ph.D.
ListedSep 15, 2022
ExchangeNASDAQ
HeadquartersBasking Ridge, NJ
CountryUnited States
Employees21
CIK0000320017
ISINUS1280583022

Market cap$14.3M
EPS (ttm)−$1.64
P/E (ttm)−0.9573
ROE-113.8%
P/B1.73
P/S142.97
Dividend yieldDiv yield
Beta0.71vs XLV 0.29

No analyst consensus on record.

Next report
Nov 5, 2026
in 63 days
EPS estimate
−$1.13
Revenue estimate
$659.0K
Fiscal quarter
Q3 FY26

EPSReportedEstimate

Feb '25May '25Aug '25Nov '25Mar '26May '26Aug '26Nov '26
Reported−$0.55−$0.55−$0.54−$0.49−$0.33−$0.50−$0.32Pending
Estimate−$0.76−$0.53−$0.65−$0.54−$0.51−$1.13
Surprise+27.6%−3.8%+16.9%+9.3%+35.3%

RevenueReportedEstimate

Feb '25May '25Aug '25Nov '25Mar '26May '26Aug '26Nov '26
Reported$1.0M$70.0K$100.0KPending
Estimate$100.0K$94.4K$659.0K
Surprise0.0%
Estimate−$1.13
ReportedDue Nov 5, 2026
Estimate$659.0K
ReportedDue Nov 5, 2026
View details

Debt to equity0.00%
Current ratio368.70%

ProfitabilityRevenueNet incomeNet margin

Q3 FY24Q4 FY24Q1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Revenue$0$1.0M$0$70.0K$0$100.0K$0$0
Net income−$4.9M−$4.6M−$4.7M−$4.7M−$4.2M−$3.0M−$4.5M−$2.9M
Net margin0.0%0.0%0.0%

GrowthOperating income

Q3 FY24Q4 FY24Q1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Operating income−$5.3M−$4.9M−$5.8M−$4.9M−$4.4M−$3.1M−$4.9M−$4.0M
YoY growth

Balance sheet, Jun 30, 2026Cash & short-term investments $10.4M · Total debt $0 · Total assets $11.0M · Shareholders' equity $8.2M

Revenue
$0
Operating income
−$4.0M
Net income
−$2.9M
View details

No dividends on record.

Institutions34 holders · as of Mar 31, 202611.74%1.06M shares
Insiders10 holders · as of Aug 26, 202615.69%1.41M shares
Otherremainder72.57%6.54M shares

9.01M company shares as of Sep 3, 2026 · institutions as of Mar 31, 2026 · holders as of their latest filing

Top shareholders13F · 13D/G · Form 4

HolderStakeSharesEvidence
Branham Justin EarlInsider
5.13%462,14813Gfiled Aug 26, 2026
David J. MazzoInsiderdirector, officer: President & CEO
3.46%311,890Form 4filed Jan 13, 2026
Vanguard Capital Management LLCInstitution
3.02%271,81513Fas of Mar 31, 2026
Renaissance Technologies LLCInstitution
1.46%131,71513Fas of Mar 31, 2026
Mohammad AzabInsiderdirector
1.16%104,925Form 4filed Jan 13, 2026
See all 25

13F — a manager's quarterly holdings · 13D/13G — an ownership statement filed at 5% or more · Form 4 — an insider's transaction report

Insider tradesForm 4

No open-market trades in the last 12 months.

View details

  • AstraZeneca (ADR)

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Compare

CompanyPriceChange
Lisata Therapeutics$1.570.00%$14.3M143.0−90.0%
AstraZeneca (ADR)$163.48+1.13%$250.67B24.315.24.1+6.4%
Merck$151.14−0.33%$374.52B121.317.65.6+5.1%
Novocure$18.30+2.61%$2.08B3.0+15.6%
Incyte$128.82+3.05%$26.11B16.453.44.5+37.7%
Median24.317.64.3+11.0%