Lisata Therapeutics (LSTA)
Develops certepetide for tumor-penetrating cancer therapy combinations.
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Develops certepetide, an investigational peptide intended to improve delivery of co-administered or tethered therapies into solid tumors. Operates as a single clinical-stage segment, relying on partners and investigator-led trials while potential economics depend on licensing, milestones, royalties, and commercialization.
Develops certepetide, a cyclic peptide being studied with other therapies to help them penetrate solid tumors through the CendR uptake pathway and modify the tumor microenvironment. The pipeline centers on clinical studies in pancreatic and biliary cancers, including investigator-led work in the United States, Australia, New Zealand, Estonia, Latvia, and Lithuania, plus partner-led development in Greater China. The company has no approved products or recurring product sales.
Operates as a single clinical-stage segment, pairing company-sponsored development with investigator trials, territorial licenses, and technology collaborations. Potential economics depend on licensing payments, development and regulatory milestones, royalties, and eventual commercial arrangements; academic sponsors, collaborators, and third parties undertake material clinical and manufacturing work. The portfolio, collaborations, and platform narrative are concentrated on certepetide, while a pending cash tender offer could replace the standalone strategy.
Company facts
No analyst consensus on record.
EPSReportedEstimate
RevenueReportedEstimate
Balance sheet, Jun 30, 2026Cash & short-term investments $10.4M · Total debt $0 · Total assets $11.0M · Shareholders' equity $8.2M
- Revenue
- $0
- Operating income
- −$4.0M
- Net income
- −$2.9M
No dividends on record.
| Institutions34 holders · as of Mar 31, 2026 | 11.74% | 1.06M shares | |
| Insiders10 holders · as of Aug 26, 2026 | 15.69% | 1.41M shares | |
| Otherremainder | 72.57% | 6.54M shares |
9.01M company shares as of Sep 3, 2026 · institutions as of Mar 31, 2026 · holders as of their latest filing
Top shareholders13F · 13D/G · Form 4
| Holder | Stake | Shares | Evidence |
|---|---|---|---|
Branham Justin EarlInsider | 5.13% | 462,148 | 13Gfiled Aug 26, 2026 ↗ |
David J. MazzoInsiderdirector, officer: President & CEO | 3.46% | 311,890 | Form 4filed Jan 13, 2026 ↗ |
Vanguard Capital Management LLCInstitution | 3.02% | 271,815 | 13Fas of Mar 31, 2026 |
Renaissance Technologies LLCInstitution | 1.46% | 131,715 | 13Fas of Mar 31, 2026 |
Mohammad AzabInsiderdirector | 1.16% | 104,925 | Form 4filed Jan 13, 2026 ↗ |
| See all 25 → | |||
13F — a manager's quarterly holdings · 13D/13G — an ownership statement filed at 5% or more · Form 4 — an insider's transaction report
Insider tradesForm 4
No open-market trades in the last 12 months.
- AstraZeneca (ADR)
Biliary-cancer rival through Imfinzi-based chemoimmunotherapy.
- Merck
Biliary-cancer rival through Keytruda-based chemoimmunotherapy.
- Novocure
Pancreatic add-on rival through Tumor Treating Fields.
- Incyte
Cholangiocarcinoma rival through FGFR2-targeted Pemazyre.
Compare
| Company | Price | Change | |||||
|---|---|---|---|---|---|---|---|
| Lisata Therapeutics | $1.57 | 0.00% | $14.3M | — | — | 143.0 | −90.0% |
| AstraZeneca (ADR) | $163.48 | +1.13% | $250.67B | 24.3 | 15.2 | 4.1 | +6.4% |
| Merck | $151.14 | −0.33% | $374.52B | 121.3 | 17.6 | 5.6 | +5.1% |
| Novocure | $18.30 | +2.61% | $2.08B | — | — | 3.0 | +15.6% |
| Incyte | $128.82 | +3.05% | $26.11B | 16.4 | 53.4 | 4.5 | +37.7% |
| Median | 24.3 | 17.6 | 4.3 | +11.0% |






