LYEL · NASDAQ · Biotechnology

Lyell Immunopharma (LYEL)

Develops CAR T-cell candidates for lymphoma and metastatic colorectal cancer.

$15.10
Pre-market+0.14 (+0.94%)
At close$14.96(+2.96%)

Breakdown13F · 13D/G · Form 4

Institutions76 holders · as of Mar 31, 202648.87%11.97M shares
Insiders10 holders · as of Aug 25, 20260.90%220.0K shares
Strategic holders3 holders · as of Jul 27, 202621.81%5.34M shares
Otherremainder28.42%6.97M shares

24.51M company shares as of Sep 3, 2026 · institutions as of Mar 31, 2026 · holders as of their latest filing

Top shareholders13F · 13D/G · Form 4

HolderStakeSharesEvidence
Arch Venture Management, LLCInstitution
13.25%3.25M13Fas of Mar 31, 2026
ARCH Venture Fund IX, L.P.Institution
13.25%3.25M13Gfiled May 15, 2026
Innovative Cellular Therapeutics Holdings LtdStrategic10 percent owner
11.32%2.77MForm 4filed Jul 27, 2026
Explore Investments LLCStrategic
6.24%1.53M13Gfiled May 8, 2026
Glaxosmithkline PLCInstitution
6.17%1.51M13Fas of Mar 31, 2026
Euler Fund, L.P.Institution
5.82%1.43M13Gfiled Apr 21, 2026
Gates Frontier, LLCStrategic
4.25%1.04M13Gfiled Aug 1, 2025
Foresite Capital Management Iv, LLCInstitution
3.27%800,39913Fas of Mar 31, 2026
Orland Properties LtdInstitution
3.08%754,69813Fas of Mar 31, 2026
Vanguard Capital Management LLCInstitution
2.93%718,15513Fas of Mar 31, 2026
Almitas Capital LLCInstitution
2.36%577,80713Fas of Mar 31, 2026
Foresite Capital Management V, LLCInstitution
1.95%477,07813Fas of Mar 31, 2026
Millennium Management LLCInstitution
1.87%458,90513Fas of Mar 31, 2026
Citadel Advisors LLCInstitution
1.56%381,46213Fas of Mar 31, 2026
Venbio Partners LLCInstitution
1.38%337,69713Fas of Mar 31, 2026
Susquehanna International Group, LLPInstitution
1.27%310,19813Fas of Mar 31, 2026
Alphabet Inc.Institution
1.20%293,25613Fas of Mar 31, 2026
BlackRock, Inc.Institution
0.78%191,82013Fas of Mar 31, 2026
Geode Capital Management, LLCInstitution
0.68%166,98013Fas of Mar 31, 2026
SC China Holding LtdInstitution
0.62%152,29913Fas of Mar 31, 2026
Marshall Wace, LLPInstitution
0.61%148,51613Fas of Mar 31, 2026
Renaissance Technologies LLCInstitution
0.48%116,41113Fas of Mar 31, 2026
Goldman Sachs Group IncInstitution
0.47%114,49113Fas of Mar 31, 2026
Velan Capital Investment Management LPInstitution
0.42%102,00013Fas of Mar 31, 2026
Mic Capital Management UK LLPInstitution
0.36%87,02813Fas of Mar 31, 2026

13F — a manager's quarterly holdings · 13D/13G — an ownership statement filed at 5% or more · Form 4 — an insider's transaction report

Institutions13F, as of Mar 31, 2026

76 holders · 11.97M shares · 19 new positions · 43 increased · 9 reduced · 12 closed

HolderShares% outstandingChg q/qFiled
Arch Venture Management, LLC3.25M13.25%+488.1KMay 15, 2026
GSK PLC1.51M6.17%0May 14, 2026
Foresite Capital Management Iv, LLC800.4K3.27%0May 15, 2026
Orland Properties Ltd754.7K3.08%0May 6, 2026
Vanguard Capital Management LLC718.2K2.93%+718.2KnewMay 15, 2026
Almitas Capital LLC577.8K2.36%0May 15, 2026
Foresite Capital Management V, LLC477.1K1.95%0May 15, 2026
Millennium Management LLC458.9K1.87%+400.3KMay 15, 2026

Ownership statements13D/G · 5% or more, as filed

Holder% of classSharesFormFiled
ARCH Venture Fund IX, L.P.13.90%3.25M13GMay 15, 2026
Innovative Cellular Therapeutics Holdings Limited12.30%3.00M13GJun 18, 2026
Innovative Cellular Therapeutics Holdings Ltd9.80%1.90M13GNov 13, 2025
Euler Fund, L.P.6.71%1.43M13GApr 21, 2026
Explore Investments LLC6.60%1.53M13GMay 8, 2026
Gates Frontier, LLC5.60%1.04M13GAug 1, 2025
Foresite Capital Fund IV, L.P.5.40%13GMay 15, 2025
James Tananbaum (“Tananbaum”)incl. Foresite Capital Fund V, L.P. (“FCF V”), Foresite Capital Management V, LLC (“FCM V”) +4 more5.30%13GOct 31, 2024

Insider tradesForm 4

Latest trades

DateInsiderTypeSharesAvg priceOwned after
Aug 21, 2026
Stephen J. Hillofficer: Chief Operating Officer
Sale989$15.5416,816
Aug 21, 2026
Lynn Seelydirector, officer: President and CEO
Sale9,589$15.5463,899
Aug 21, 2026
Gary K. Leeofficer: Chief Scientific Officer
Sale1,457$15.5416,220
Aug 10, 2026
Gary K. Leeofficer: Chief Scientific Officer
Sale131$14.3417,677
Aug 10, 2026
Veronica Sanchez Bulisofficer: VP, Corporate Controller
Sale621$14.3414,799
Aug 10, 2026
Stephen J. Hillofficer: Chief Operating Officer
Sale89$14.3417,805
Aug 10, 2026
Lynn Seelydirector, officer: President and CEO
Sale390$14.3473,488
Jul 17, 2026
Innovative Cellular Therapeutics Holdings Ltd10 percent owner
Sale10$13.702,857,480
Jul 16, 2026
Innovative Cellular Therapeutics Holdings Ltd10 percent owner
Sale10$13.732,857,490
May 11, 2026
Veronica Sanchez Bulisofficer: VP, Corporate Controller
Sale217$18.9115,420

CongressHouse and Senate disclosures

Not reported.