MDGL · NASDAQ · Biotechnology

Madrigal Pharmaceuticals

Commercializes Rezdiffra and develops combination therapies for MASH.

$533.76
After-hours close−0.11 (−0.02%)
At close$533.87(−1.81%)

Breakdown13F · Form 4

Institutions 142.79%Insiders 14.04%

A 13F quarter can total more than the shares outstanding — sub-advisers file the same block twice, and a filer's own share count can be a quarter stale. No split is drawn from it.

Shares outstanding 23.10M · Float

Float — provider float is below the insider stake.

The provider's float is smaller than the insider stake it should exclude, so it is not shown.

Top shareholders13F · 13D/G · Form 4

HolderShares% outstandingFormFiled
Baker Bros. Advisors LP2.14M9.28%13FAug 14, 2026
Janus Henderson Group PLC2.02M8.80%13GMay 15, 2026
RTW Investments, LP1.99M8.63%13FAug 14, 2026
Roderick Wong, M.D.1.99M9.20%13GNov 14, 2024
Jupiter Topco LLC1.94M8.38%13FAug 14, 2026

Institutions13F, as of Jun 30, 2026

437 holders · 32.99M shares · 79 new positions · 220 increased · 136 reduced · 45 closed

HolderShares% outstandingChg q/qFiled
Baker Bros. Advisors LP2.14M9.28%+1.4KAug 14, 2026
RTW Investments, LP1.99M8.63%0Aug 14, 2026
Jupiter Topco LLC1.94M8.38%+1.94MnewAug 14, 2026
Avoro Capital Advisors LLC1.83M7.94%+15.2KAug 14, 2026
Paulson & Co. Inc.1.34M5.80%−52.2KAug 14, 2026
BlackRock, Inc.1.20M5.20%−359.2KAug 7, 2026
Vanguard Capital Management LLC835.7K3.62%+8.5KAug 13, 2026
Wellington Management Group LLP825.7K3.57%+130.8KAug 14, 2026

Beneficial owners13D/G · 5% or more, as filed

Holder% of classSharesFormFiled
Roderick Wong, M.D.incl. RTW Investments, LP9.20%1.99M13GNov 14, 2024
Janus Henderson Group PLC8.80%2.02M13GMay 15, 2026
Paul A Friedman, M.D.7.80%1.81M13DDec 12, 2025
Rebecca Taub, M.D.7.80%1.81M13DDec 12, 2025
Paulson & Co. Inc.6.10%1.39M13GMay 15, 2026

InsidersForm 4

InsiderRoleShares% outstandingFiled
Baker Bros. Advisors LPdirector1.95M8.44%Jun 18, 2026
Rebecca Taubdirector452.7K1.96%Jun 18, 2026
Fred B. Cravesdirector361.1K1.56%Mar 14, 2025
William John Sibolddirector, officer: President and CEO209.3K0.91%Jul 20, 2026
Paul A. Friedmandirector187.2K0.81%Jan 13, 2026
Richard S. Levydirector22.5K0.10%Jun 18, 2026
Carole Huntsmanofficer: Chief Commercial Officer12.7K0.05%Mar 6, 2026
Mardi Dierofficer: EVP and CFO12.5K0.05%Mar 6, 2026
Shannon T. Kelleyofficer: General Counsel11.5K0.05%Aug 20, 2026
David Soergelofficer: Chief Medical Officer10.0K0.04%Jun 1, 2026

2 ten-percent owners hold 250.3K shares by Form 4, outside the officers-and-directors figure above · 28 people have not refiled in the last 18 months (226.8K shares), so they are not in the figure above

Latest trades

DateInsiderTypeSharesAvg priceOwned after
Aug 17, 2026
Shannon T. Kelleyofficer: General Counsel
Sale664$514.9711,474
Jul 20, 2026
William John Sibolddirector, officer: President and CEO
Sale · 10 lots2,500$547.30209,329
Jun 1, 2026
David Soergelofficer: Chief Medical Officer
Sale1,042$495.7410,033
May 22, 2026
Richard S. Levydirector
Sale · 12 lots5,682$515.4422,015
May 18, 2026
David Soergelofficer: Chief Medical Officer
Sale844$515.9011,075
Mar 6, 2026
Rebecca Taubdirector
Sale491$431.94452,213
Mar 6, 2026
Carole Huntsmanofficer: Chief Commercial Officer
Sale419$431.9412,692
Mar 6, 2026
Shannon T. Kelleyofficer: General Counsel
Sale360$431.9412,138
Mar 6, 2026
William John Sibolddirector, officer: President and CEO
Sale1,663$431.94161,829
Mar 6, 2026
Mardi Dierofficer: EVP and CFO
Sale · 12 lots1,982$430.8712,490

CongressHouse and Senate disclosures

Not reported.