MLYS · NASDAQ · Biotechnology

Mineralys Therapeutics (MLYS)

Develops lorundrostat for uncontrolled hypertension and related cardiorenal conditions.

$29.03
Pre-market−0.02 (−0.07%)
At close$29.05(+13.61%)

Breakdown13F · 13D/G · Form 4

Institutions241 holders · as of Jun 30, 2026 · largest filers plus last quarter's tail≈ 112.17%99.16M shares
Insiders11 holders · as of Aug 25, 20268.83%7.81M shares
Strategic holders1 holder · as of Mar 17, 20256.42%5.67M shares
Adds to127.42%

88.41M company shares as of Sep 3, 2026 · institutions as of Jun 30, 2026 · holders as of their latest filing

This quarter's institutional total failed a plausibility check; shown: the largest filers plus last quarter's remainder.

These groups come from separate filings that can overlap, so they add to 127.42%; nothing is left for Other.

Top shareholders13F · 13D/G · Form 4

HolderStakeSharesEvidence
Catalys Pacific Fund, LPInstitution
9.05%8.00M13Gfiled Feb 13, 2026
Catalys Pacific, LLCInstitution
8.94%7.90M13Fas of Jun 30, 2026
Ra Capital Management, L.P.Institution
8.70%7.69M13Fas of Jun 30, 2026
Srinivas AkkarajuInsider
7.18%6.35M13Dfiled Sep 8, 2025
BlackRock, Inc.Institution
6.66%5.89M13Fas of Jun 30, 2026
Samsara Biocapital, LLCInstitution
6.64%5.87M13Fas of Jun 30, 2026
Samsara BioCapital GP, LLCStrategic10 percent owner
6.42%5.67MForm 4filed Mar 17, 2025
FMR LLCInstitution
5.10%4.51M13Fas of Jun 30, 2026
State Street CorpInstitution
4.68%4.14M13Fas of Jun 30, 2026
Deerfield Management Company, L.P. (Series C)Institution
4.48%3.96M13Fas of Jun 30, 2026
Vanguard Capital Management LLCInstitution
3.12%2.76M13Fas of Jun 30, 2026
Laurion Capital Management LPInstitution
2.83%2.51M13Fas of Jun 30, 2026
Price T Rowe Associates Inc /MD/Institution
2.56%2.26M13Fas of Jun 30, 2026
Orbimed Advisors LLCInstitution
2.39%2.11M13Fas of Jun 30, 2026
Capital World InvestorsInstitution
2.26%2.00M13Fas of Jun 30, 2026
Armistice Capital, LLCInstitution
1.96%1.74M13Fas of Jun 30, 2026
Troluce Capital Advisors LLCInstitution
1.96%1.73M13Fas of Jun 30, 2026
Franklin Resources IncInstitution
1.85%1.64M13Fas of Jun 30, 2026
Andera PartnersInstitution
1.80%1.59M13Fas of Jun 30, 2026
Geode Capital Management, LLCInstitution
1.79%1.58M13Fas of Jun 30, 2026
Sr One Capital Management, LPInstitution
1.77%1.56M13Fas of Jun 30, 2026
Bank of America Corp /DE/Institution
1.70%1.51M13Fas of Jun 30, 2026
Sphera Funds Management Ltd.Institution
1.66%1.47M13Fas of Jun 30, 2026
Goldman Sachs Group IncInstitution
1.65%1.46M13Fas of Jun 30, 2026
Pictet Asset Management Holding SAInstitution
1.62%1.43M13Fas of Jun 30, 2026

13F — a manager's quarterly holdings · 13D/13G — an ownership statement filed at 5% or more · Form 4 — an insider's transaction report

Institutions13F, as of Jun 30, 2026

241 holders · 99.16M shares · 38 new positions · 122 increased · 71 reduced · 25 closed

HolderShares% outstandingChg q/qFiled
Catalys Pacific, LLC7.90M8.94%0Aug 5, 2026
Ra Capital Management, L.P.7.69M8.70%0Aug 14, 2026
BlackRock, Inc.5.89M6.66%+1.41MAug 7, 2026
Samsara Biocapital, LLC5.87M6.64%0Aug 14, 2026
FMR LLC4.51M5.10%−349.4KAug 13, 2026
State Street Corp4.14M4.68%+1.21MAug 7, 2026
Deerfield Management Company, L.P. (Series C)3.96M4.48%+3.96MnewAug 14, 2026
Vanguard Capital Management LLC2.76M3.12%+302.4KAug 13, 2026

Ownership statements13D/G · 5% or more, as filed

Holder% of classSharesFormFiled
Catalys Pacific Fund, LP10.10%8.00M13GFeb 13, 2026
RA Capital Management, L.P.incl. Peter Kolchinsky, Rajeev Shah +1 more9.90%7.80M13DSep 8, 2025
Srinivas Akkarajuincl. Samsara Opportunity Fund, L.P., Samsara Opportunity Fund GP, LLC +2 more8.20%6.35M13DSep 8, 2025
FMR LLC6.30%5.02M13GFeb 5, 2026
BlackRock, Inc.5.20%4.11M13GJan 21, 2026

Insider tradesForm 4

Latest trades

DateInsiderTypeSharesAvg priceOwned after
Aug 21, 2026
Eric Warrenofficer: Chief Commercial Officer
Sale7,437$25.9838,400
Aug 10, 2026
David Malcom Rodmanofficer: Chief Medical Officer
Sale2,170$27.0951,384
Jul 21, 2026
Eric Warrenofficer: Chief Commercial Officer
Sale7,438$26.8738,400
Jul 17, 2026
David Malcom Rodmanofficer: Chief Medical Officer
Sale416$26.5351,384
Jul 15, 2026
David Malcom Rodmanofficer: Chief Medical Officer
Sale6,349$26.6151,384
Jul 13, 2026
David Malcom Rodmanofficer: Chief Medical Officer
Sale14,058$27.5857,733
Jul 13, 2026
Jon Congletondirector, officer: Chief Executive Officer
Sale10,700$27.24603,621
Jul 9, 2026
David Malcom Rodmanofficer: Chief Medical Officer
Sale2,171$30.3057,733
Jun 26, 2026
Eric Warrenofficer: Chief Commercial Officer
Sale104,124$25.9038,400
Jun 30, 2026
Jon Congletondirector, officer: Chief Executive Officer
Sale · 2 lots75,000$26.14614,321

CongressHouse and Senate disclosures

Not reported.