MNPR · NASDAQ · Biotechnology

Monopar Therapeutics

Develops ALXN1840 for Wilson disease and MNPR-101 radiopharmaceuticals for oncology.

$111.89
After-hours close−0.50 (−0.44%)
At close$112.39(−1.36%)

Breakdown13F · Form 4

Institutions 93.09%6.24M sharesInsiders 3.86%258.3K sharesOther 3.05%204.8K shares

Shares outstanding 6.70M · Float 4.16M · 62.2% free float

Top shareholders13F · 13D/G · Form 4

HolderShares% outstandingFormFiled
Janus Henderson Group PLC1.32M19.67%13FMay 18, 2026
Ra Capital Management, L.P.667.2K9.96%13FMay 15, 2026
Hendricks Diane · 10 percent owner567.6K8.47%Form 4Dec 17, 2025
Ein #562.5K10.90%13D/GNov 6, 2024
AstraZeneca PLC522.7K7.80%13GFeb 6, 2026

Institutions13F, as of Mar 31, 2026

82 holders · 6.24M shares · 21 new positions · 53 increased · 18 reduced · 12 closed

HolderShares% outstandingChg q/qFiled
Janus Henderson Group PLC1.32M19.67%0May 18, 2026
Ra Capital Management, L.P.667.2K9.96%0May 15, 2026
Saturn V Capital Management LLC345.6K5.16%+19.9KMay 15, 2026
Deerfield Management Company, L.P. (Series C)323.7K4.83%+153.2KMay 15, 2026
BlackRock, Inc.316.6K4.73%+61.7KMay 13, 2026
Adage Capital Partners GP, L.L.C.309.2K4.62%−330.3KMay 15, 2026
Siren, L.L.C.270.1K4.03%+57.8KMay 14, 2026
Adar1 Capital Management, LLC264.3K3.95%+30.4KMay 18, 2026

Beneficial owners13D/G · 5% or more, as filed

Holder% of classSharesFormFiled
Janus Henderson Group PLC19.50%1.29M13GNov 14, 2025
Ein #10.90%562.5KNov 6, 2024
RA Capital Management, L.P.9.90%667.6K13GFeb 17, 2026
Alexion Pharmaceuticals, Inc.incl. AstraZeneca PLC9.90%387.3K13GOct 28, 2024
Peter Kolchinskyincl. Rajeev Shah, RA Capital Management, L.P. +1 more9.70%511.2K13GOct 31, 2024
AstraZeneca PLC7.80%522.7K13GFeb 6, 2026
Adage Capital Management, L.P.6.23%424.2K13GMay 13, 2026
Saturn V Capital Management LP5.20%345.6K13GMay 15, 2026
Tang Capital Management, LLC5.10%200.0KOct 24, 2024

InsidersForm 4

InsiderRoleShares% outstandingFiled
Hendricks Diane10 percent owner567.6K8.47%Dec 17, 2025
Tactic Pharma LLC10 percent owner272.0K4.06%Sep 26, 2025
Chandler Robinsondirector, officer: Chief Executive Officer162.1K2.42%Jul 2, 2026
Andrew Cittadineofficer: Chief Operating Officer55.6K0.83%Jul 2, 2026
Lavina Talukdardirector14.0K0.21%Mar 6, 2025
Arthur J. Klausnerdirector8.8K0.13%Dec 19, 2025
Raymond Andersondirector5.4K0.08%Aug 28, 2026
Christopher M. Starrdirector5.2K0.08%Jul 16, 2025
Patrice Riouxother: Acting Chief Medical Officer5.1K0.08%Aug 27, 2026
Quan Anh Vuofficer: Chief Financial Officer2.2K0.03%Jul 2, 2026

4 ten-percent owners hold 1.45M shares by Form 4, outside the officers-and-directors figure above · 3 people have not refiled in the last 18 months (53.1K shares), so they are not in the figure above

Latest trades

DateInsiderTypeSharesAvg priceOwned after
Aug 26, 2026
Kim R. Tsuchimotodirector
Sale · 6 lots4,090$111.390
Aug 25, 2026
Raymond Andersondirector
Sale · 4 lots3,788$111.655,373
Aug 26, 2026
Patrice Riouxother: Acting Chief Medical Officer
Sale1$111.265,065
Dec 26, 2025
Quan Anh Vuofficer: Chief Financial Officer
Purchase1,500$69.951,500
Dec 18, 2025
Arthur J. Klausnerdirector
Sale · 2 lots5,121$67.158,762
Sep 24, 2025
Tactic Pharma LLC10 percent owner
Sale550,229$63.61272,026

CongressHouse and Senate disclosures

Not reported.