OPK · NASDAQ · Medical - Diagnostics & Research

OPKO Health

Runs BioReference diagnostics alongside Rayaldee and NGENLA economics.

$1.46
After-hours close−0.03 (−1.68%)
At close$1.49(−1.00%)

Breakdown13F · Form 4

Institutions 27.67%206.50M sharesInsiders 30.33%226.38M sharesOther 42.00%313.44M shares

Shares outstanding 746.33M · Float 323.73M · 43.4% free float

Top shareholders13F · 13D/G · Form 4

HolderShares% outstandingFormFiled
Frost Phillip MD et al255.43M34.10%13DJul 1, 2026
Rubric Capital Management LP47.79M6.40%13FAug 14, 2026
BlackRock, Inc.36.98M4.95%13FAug 7, 2026
Vanguard Capital Management LLC14.97M2.01%13FAug 13, 2026
Vanguard Portfolio Management LLC14.93M2.00%13FAug 13, 2026

Institutions13F, as of Jun 30, 2026

229 holders · 206.50M shares · 25 new positions · 99 increased · 52 reduced · 35 closed

HolderShares% outstandingChg q/qFiled
Rubric Capital Management LP47.79M6.40%0Aug 14, 2026
BlackRock, Inc.36.98M4.95%+746.7KAug 7, 2026
Vanguard Capital Management LLC14.97M2.01%+469.8KAug 13, 2026
Vanguard Portfolio Management LLC14.93M2.00%+165.2KAug 13, 2026
Geode Capital Management, LLC11.58M1.55%+279.5KAug 12, 2026
State Street Corp10.31M1.38%+807.7KAug 7, 2026
Goldman Sachs Group Inc7.04M0.94%−639.5KAug 14, 2026
UBS Group AG5.01M0.67%−1.07MAug 13, 2026

Beneficial owners13D/G · 5% or more, as filed

Holder% of classSharesFormFiled
Frost Phillip MD et alincl. Frost Nevada Investments Trust, Frost Gamma Investments Trust34.10%255.43M13DJul 1, 2026
Rubric Capital Management LPincl. David Rosen6.98%48.71M13GNov 13, 2024

InsidersForm 4

InsiderRoleShares% outstandingFiled
Phillip Md Et Al Frostdirector, 10 percent owner, officer: CEO & Chairman216.23M28.97%Nov 21, 2025
Steven D. Rubindirector, officer: Executive VP-Administration6.57M0.88%Jul 28, 2026
Subbarao V. Uppaluridirector2.62M0.35%Mar 20, 2026
Adam Logalofficer: Sr. Vice President, CFO563.4K0.08%Jul 28, 2026
John A. Paganellidirector394.3K0.05%Mar 20, 2026

14 people have not refiled in the last 18 months (229.21M shares), so they are not in the figure above

Latest trades

DateInsiderTypeSharesAvg priceOwned after
Mar 20, 2026
John A. Paganellidirector
Purchase10,000$1.14394,340
Nov 21, 2025
Phillip Md Et Al Frostdirector, 10 percent owner, officer: CEO & Chairman
Purchase · 5 lots580,000$1.33216,706,448
Nov 20, 2025
Phillip Md Et Al Frostdirector, 10 percent owner, officer: CEO & Chairman
Purchase · 7 lots580,000$1.33216,126,448
Nov 19, 2025
Phillip Md Et Al Frostdirector, 10 percent owner, officer: CEO & Chairman
Purchase · 9 lots580,000$1.31215,546,448
Nov 18, 2025
Phillip Md Et Al Frostdirector, 10 percent owner, officer: CEO & Chairman
Purchase · 11 lots533,300$1.27214,966,448
Oct 31, 2025
Phillip Md Et Al Frostdirector, 10 percent owner, officer: CEO & Chairman
Purchase150,000$1.42214,386,448

CongressHouse and Senate disclosures

Not reported.