PRME · NASDAQ · Biotechnology

Prime Medicine

Develops Prime Editing therapies for liver, lung, and partnered cell-therapy programs.

$3.59
After-hours close−0.02 (−0.61%)
At close$3.61(−0.77%)

Breakdown13F · Form 4

Institutions 59.80%108.00M sharesInsiders 3.59%6.48M sharesOther 36.61%66.14M shares

Shares outstanding 180.62M · Float 59.17M · 32.8% free float

Top shareholders13F · 13D/G · Form 4

HolderShares% outstandingFormFiled
Liu David R. · 10 percent owner20.24M11.21%Form 4Jul 1, 2025
Robert Nelsen18.59M10.40%13DAug 11, 2025
Alphabet Inc.16.56M9.17%13FAug 7, 2026
Bristol-Myers Squibb Company11.01M8.40%13GOct 4, 2024
GV 2019, L.P.10.10M7.50%13GNov 12, 2025

Institutions13F, as of Jun 30, 2026

194 holders · 108.00M shares · 24 new positions · 87 increased · 69 reduced · 27 closed

HolderShares% outstandingChg q/qFiled
Alphabet Inc.16.56M9.17%0Aug 7, 2026
BlackRock, Inc.9.60M5.32%+1.10MAug 7, 2026
Ark Investment Management LLC8.35M4.62%+2.10MAug 14, 2026
State Street Corp7.58M4.19%+1.23MAug 7, 2026
T. Rowe Price Investment Management, Inc.5.24M2.90%−244.6KAug 14, 2026
Vanguard Capital Management LLC4.52M2.50%+48.5KAug 13, 2026
Balyasny Asset Management L.P.3.97M2.20%−154.3KAug 14, 2026
Goldman Sachs Group Inc3.43M1.90%+2.46MAug 14, 2026

Beneficial owners13D/G · 5% or more, as filed

Holder% of classSharesFormFiled
Robert Nelsenincl. ARCH Venture Fund XII, L.P., Steven Gillis +9 more10.40%18.59M13DAug 11, 2025
Bristol-Myers Squibb Company8.40%11.01M13GOct 4, 2024
GV 2019, L.P.7.50%10.10M13GNov 12, 2025

InsidersForm 4

InsiderRoleShares% outstandingFiled
Liu David R.10 percent owner20.24M11.21%Jul 1, 2025
Robert Nelsendirector, 10 percent owner: 6.23M3.45%Aug 1, 2025
GV 2021 GP, L.L.C.10 percent owner3.26M1.81%Aug 5, 2025
Allan Reinedirector, officer: Chief Executive Officer125.0K0.07%May 22, 2025
Ann L. Leeofficer: Chief Technical Officer100.0K0.06%May 22, 2025
Richard Brudnickofficer: Chief Business Officer20.0K0.01%May 22, 2025

5 ten-percent owners hold 33.10M shares by Form 4, outside the officers-and-directors figure above · 5 people have not refiled in the last 18 months (6.20M shares), so they are not in the figure above

Latest trades

No open-market trades in the last 12 months.

CongressHouse and Senate disclosures

Not reported.