PTGX · NASDAQ · Biotechnology

Protagonist Therapeutics

Discovers peptide medicines and earns collaboration economics from partnered ICOTYDE and rusfertide.

$146.05
After-hours close+1.78 (+1.23%)
At close$144.27(−3.50%)

Breakdown13F · Form 4

Institutions 129.91%Insiders 1.19%

A 13F quarter can total more than the shares outstanding — sub-advisers file the same block twice, and a filer's own share count can be a quarter stale. No split is drawn from it.

Shares outstanding 64.31M · Float 52.49M · 81.6% free float

Top shareholders13F · 13D/G · Form 4

HolderShares% outstandingFormFiled
BlackRock, Inc.10.31M16.03%13FAug 7, 2026
Farallon Capital Management LLC6.35M9.87%13FAug 14, 2026
RTW Investments, LP5.06M7.87%13FAug 14, 2026
Vanguard Portfolio Management LLC3.63M5.64%13FAug 13, 2026
Wellington Management Group LLP3.42M5.31%13FAug 14, 2026

Institutions13F, as of Jun 30, 2026

357 holders · 83.55M shares · 63 new positions · 208 increased · 87 reduced · 40 closed

HolderShares% outstandingChg q/qFiled
BlackRock, Inc.10.31M16.03%+528.5KAug 7, 2026
Farallon Capital Management LLC6.35M9.87%0Aug 14, 2026
RTW Investments, LP5.06M7.87%+2.1KAug 14, 2026
Vanguard Portfolio Management LLC3.63M5.64%+148.1KAug 13, 2026
Wellington Management Group LLP3.42M5.31%−182.9KAug 14, 2026
UBS Group AG3.40M5.29%−1.78MAug 13, 2026
State Street Corp3.32M5.16%+204.8KAug 7, 2026
Vanguard Capital Management LLC2.85M4.44%+47.5KAug 13, 2026

Beneficial owners13D/G · 5% or more, as filed

Holder% of classSharesFormFiled
BlackRock, Inc.13.80%8.58M13GOct 17, 2025
RTW Investments, LP8.10%5.06M13GFeb 17, 2026
Vanguard Portfolio Management5.53%3.53M13GApr 29, 2026
State Street Corporation5.40%3.18MOct 16, 2024
Wellington Management Group LLP5.10%3.17M13GFeb 10, 2026
Vanguard Capital Management5.09%3.25M13GApr 30, 2026

InsidersForm 4

InsiderRoleShares% outstandingFiled
Dinesh V. Ph D. Pateldirector, officer: President and CEO523.5K0.81%Aug 12, 2026
Arturo Md Molinaofficer: Chief Medical Officer84.1K0.13%Mar 27, 2026
Harold E. Selickdirector60.8K0.09%Mar 27, 2026
Asif Aliofficer: Chief Financial Officer59.0K0.09%Apr 21, 2026
Bryan Giraudodirector12.7K0.02%May 11, 2026
William D. Waddilldirector7.8K0.01%Jun 25, 2026
Lewis T. Williamsdirector7.8K0.01%Feb 18, 2026
Sarah A. O'Dowddirector7.8K0.01%Jan 6, 2026

4 ten-percent owners hold 5.35M shares by Form 4, outside the officers-and-directors figure above · 9 people have not refiled in the last 18 months (2.53M shares), so they are not in the figure above

Latest trades

DateInsiderTypeSharesAvg priceOwned after
Aug 11, 2026
Dinesh V. Ph D. Pateldirector, officer: President and CEO
Sale34,239$148.52523,478
Aug 10, 2026
Dinesh V. Ph D. Pateldirector, officer: President and CEO
Sale65,761$149.11523,478
Jun 23, 2026
William D. Waddilldirector
Sale9,000$117.947,825
Jun 10, 2026
William D. Waddilldirector
Sale9,000$107.687,825
May 29, 2026
William D. Waddilldirector
Sale9,000$99.647,825
May 12, 2026
Dinesh V. Ph D. Pateldirector, officer: President and CEO
Sale75,000$100.12523,478
May 8, 2026
Bryan Giraudodirector
Sale · 2 lots11,130$100.0012,695
May 7, 2026
Bryan Giraudodirector
Sale · 2 lots48,000$100.1233,825
Apr 20, 2026
Asif Aliofficer: Chief Financial Officer
Sale1,750$105.4759,003
Mar 26, 2026
Asif Aliofficer: Chief Financial Officer
Sale24,765$104.2460,753

CongressHouse and Senate disclosures

Not reported.