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SABS · NASDAQ · Biotechnology

SAB Biotherapeutics (SABS)

Develops a fully human polyclonal-antibody therapy for newly diagnosed autoimmune diabetes.

$3.60

Pre-market−0.15 (−4.00%)

At close$3.75(+1.35%)

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Breakdown13F · 13D/G · Form 4

Institutions81 holders · as of Mar 31, 2026	76.05%	69.19M shares
Insiders1 holder · as of Jun 26, 2026	0.05%	42.3K shares
Otherremainder	23.90%	21.75M shares

90.99M company shares as of Sep 3, 2026 · institutions as of Mar 31, 2026 · holders as of their latest filing

Top shareholders13F · 13D/G · Form 4

Holder	Stake	Shares	Evidence
Vivo Capital, LLCInstitution	12.55%	11.42M	13Fas of Mar 31, 2026
Caligan Partners LPInstitution	8.76%	7.97M	13Fas of Mar 31, 2026
Perceptive Advisors LLCInstitution	7.07%	6.43M	13Fas of Mar 31, 2026
Adage Capital Management, L.P.Institution	7.04%	6.41M	13Gfiled Aug 12, 2026 ↗
Commodore Capital LPInstitution	4.84%	4.40M	13Fas of Mar 31, 2026
Ra Capital Management, L.P.Institution	4.84%	4.40M	13Fas of Mar 31, 2026
Balyasny Asset Management L.P.Institution	4.13%	3.76M	13Fas of Mar 31, 2026
Adage Capital Partners GP, L.L.C.Institution	3.74%	3.41M	13Fas of Mar 31, 2026
Millennium Management LLCInstitution	3.33%	3.03M	13Fas of Mar 31, 2026
Woodline Partners LPInstitution	3.13%	2.85M	13Fas of Mar 31, 2026
Vanguard Capital Management LLCInstitution	2.74%	2.49M	13Fas of Mar 31, 2026
Spruce Street Capital LPInstitution	2.42%	2.20M	13Fas of Mar 31, 2026
Sessa Capital Im, L.P.Institution	2.42%	2.20M	13Fas of Mar 31, 2026
Boothbay Fund Management, LLCInstitution	1.63%	1.48M	13Fas of Mar 31, 2026
Ameriprise Financial IncInstitution	1.62%	1.48M	13Fas of Mar 31, 2026
Ensign Peak Advisors, IncInstitution	1.51%	1.38M	13Fas of Mar 31, 2026
Soleus Capital Management, L.P.Institution	1.15%	1.05M	13Fas of Mar 31, 2026
Propel Bio Management, LLCInstitution	1.11%	1.01M	13Fas of Mar 31, 2026
Jefferies Financial Group Inc.Institution	0.99%	903,094	13Fas of Mar 31, 2026
Blackstone Inc.Institution	0.95%	860,170	13Fas of Mar 31, 2026
Exoduspoint Capital Management, LPInstitution	0.84%	768,627	13Fas of Mar 31, 2026
Affinity Asset Advisors, LLCInstitution	0.63%	575,000	13Fas of Mar 31, 2026
Monashee Investment Management LLCInstitution	0.55%	500,000	13Fas of Mar 31, 2026
Marshall Wace, LLPInstitution	0.51%	463,925	13Fas of Mar 31, 2026
Awm Investment Company, Inc.Institution	0.44%	400,000	13Fas of Mar 31, 2026

13F — a manager's quarterly holdings · 13D/13G — an ownership statement filed at 5% or more

Institutions13F, as of Mar 31, 2026

81 holders · 69.19M shares · 35 new positions · 60 increased · 7 reduced · 5 closed

Holder	Shares	% outstanding	Chg q/q	Filed
Vivo Capital, LLC	11.42M	12.55%	0	May 20, 2026
Caligan Partners LP	7.97M	8.76%	+7.97Mnew	May 15, 2026
Perceptive Advisors LLC	6.43M	7.07%	+5.63M	May 29, 2026
Commodore Capital LP	4.40M	4.84%	0	May 15, 2026
Ra Capital Management, L.P.	4.40M	4.84%	0	May 15, 2026
Balyasny Asset Management L.P.	3.76M	4.13%	+3.29M	May 15, 2026
Adage Capital Partners GP, L.L.C.	3.41M	3.74%	+3.41Mnew	May 15, 2026
Millennium Management LLC	3.03M	3.33%	+2.71M	May 15, 2026

Ownership statements13D/G · 5% or more, as filed

Holder	% of class	Shares	Form	Filed
Caligan Partners LP	10.40%	7.70M	13G	May 15, 2026 ↗
Balyasny Asset Management L.P.	9.99%	5.09M	13G	May 15, 2026 ↗
Vivo Opportunity Fund Holdings, L.P.	9.99%	25.93M	13G	Oct 3, 2025 ↗
Rajeev Shahincl. RA Capital Management, L.P., RA Capital Healthcare Fund, L.P. +1 more	9.90%	9.61M	13D	Aug 10, 2026 ↗
Woodline Partners LP	9.90%	7.13M	13G	Nov 14, 2025 ↗
Commodore Capital LP	9.90%	4.52M	13G	Oct 3, 2025 ↗
Perceptive Advisors LLC	8.40%	6.43M	13G	May 15, 2026 ↗
Adage Capital Management, L.P.	8.38%	6.41M	13G	Aug 12, 2026 ↗
Millennium Management LLC	5.10%	3.43M	13G	May 1, 2026 ↗
Biotechnology Value Fund L P	5.10%	2.54M	13G	Feb 17, 2026 ↗

SAB Biotherapeutics (SABS)

Breakdown13F · 13D/G · Form 4

Top shareholders13F · 13D/G · Form 4

Institutions13F, as of Mar 31, 2026

Ownership statements13D/G · 5% or more, as filed

Insider tradesForm 4

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