ARWR · NASDAQ · Biotechnology

Arrowhead Pharmaceuticals

Develops targeted RNAi medicines and markets REDEMPLO for familial chylomicronemia syndrome.

$84.80
After-hours close−0.11 (−0.13%)
At close$84.91(−4.15%)

Breakdown13F · Form 4

Institutions 93.36%131.50M sharesInsiders 3.59%5.06M sharesOther 3.05%4.29M shares

Shares outstanding 140.86M · Float 122.78M · 87.2% free float

Top shareholders13F · 13D/G · Form 4

HolderShares% outstandingFormFiled
BlackRock, Inc.14.83M10.53%13FAug 7, 2026
Avoro Capital Advisors LLC11.36M8.06%13FAug 14, 2026
FMR LLC8.04M5.71%13FAug 13, 2026
Vanguard Portfolio Management LLC6.35M4.51%13FAug 13, 2026
Vanguard Capital Management LLC6.11M4.34%13FAug 13, 2026

Institutions13F, as of Jun 30, 2026

521 holders · 131.50M shares · 126 new positions · 281 increased · 161 reduced · 63 closed

HolderShares% outstandingChg q/qFiled
BlackRock, Inc.14.83M10.53%−3.33MAug 7, 2026
Avoro Capital Advisors LLC11.36M8.06%+655.6KAug 14, 2026
FMR LLC8.04M5.71%+773.2KAug 13, 2026
Vanguard Portfolio Management LLC6.35M4.51%−794.8KAug 13, 2026
Vanguard Capital Management LLC6.11M4.34%+78.5KAug 13, 2026
State Street Corp5.69M4.04%−801.5KAug 7, 2026
Norges Bank3.90M2.77%+3.90MnewAug 12, 2026
Invesco Ltd.3.88M2.76%+603.3KAug 14, 2026

Beneficial owners13D/G · 5% or more, as filed

Holder% of classSharesFormFiled
BlackRock, Inc.12.20%17.10M13GApr 24, 2026
Avoro Capital Advisors LLC8.30%11.52M13GAug 14, 2025
FMR LLC5.20%7.35M13GMay 6, 2026
Vanguard Portfolio Management5.19%7.27M13GApr 28, 2026
State Street Corporation5.10%6.35MOct 16, 2024
Vanguard Capital Management5.05%7.08M13GApr 29, 2026

InsidersForm 4

InsiderRoleShares% outstandingFiled
Christopher Richard Anzalonedirector, officer: Chief Executive Officer3.79M2.69%Jan 5, 2026
Patrick O'Brienofficer: COO472.8K0.34%Jan 8, 2026
James C. Hamiltonofficer: Chief Medical Officer227.0K0.16%Apr 24, 2026
Daniel Joseph Apelofficer: Chief Financial Officer162.9K0.12%Apr 24, 2026
Michael S. Perrydirector111.5K0.08%Aug 20, 2026
Mauro Ferraridirector69.1K0.05%Dec 30, 2025
Hongbo Ludirector57.7K0.04%May 14, 2026
William D. Waddilldirector56.6K0.04%Dec 23, 2025
Douglas S. Ingramdirector46.2K0.03%Dec 18, 2025
Victoria Vakienerdirector35.7K0.03%Dec 23, 2025

2 ten-percent owners hold 279.4K shares by Form 4, outside the officers-and-directors figure above · 15 people have not refiled in the last 18 months (2.48M shares), so they are not in the figure above

Latest trades

DateInsiderTypeSharesAvg priceOwned after
Aug 18, 2026
Adeoye Y. Olukotundirector
Sale2,000$86.9631,600
Aug 18, 2026
Michael S. Perrydirector
Sale11,600$87.30111,459
May 12, 2026
Hongbo Ludirector
Sale2,970$76.8852,012
Apr 23, 2026
James C. Hamiltonofficer: Chief Medical Officer
Sale10,000$75.00226,958
Apr 22, 2026
Daniel Joseph Apelofficer: Chief Financial Officer
Sale · 3 lots13,095$71.35162,905
Mar 5, 2026
James C. Hamiltonofficer: Chief Medical Officer
Sale10,000$64.19236,958
Jan 2, 2026
Christopher Richard Anzalonedirector, officer: Chief Executive Officer
Sale · 2 lots13,187$66.103,792,739
Jan 5, 2026
James C. Hamiltonofficer: Chief Medical Officer
Sale · 7 lots40,164$63.11171,958
Jan 5, 2026
Patrick O'Brienofficer: COO
Sale · 12 lots49,493$63.11474,908
Dec 26, 2025
Mauro Ferraridirector
Sale7,530$70.0069,053

CongressHouse and Senate disclosures

Not reported.