Alterity Therapeutics (ADR) (ATHE)
Develops ATH434, a clinical candidate for multiple system atrophy and related Parkinsonian disorders.
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Advances ATH434, a small-molecule clinical candidate for multiple system atrophy and related Parkinsonian disorders. The Melbourne-based company has no approved product described in its latest filing and depends on clinical, regulatory, and financing progress.
Advances ATH434, a small molecule designed to inhibit pathological protein aggregation and restore normal iron balance in the brain. The clinical program focuses on multiple system atrophy and related Parkinsonian disorders, following earlier Prana-era work on Alzheimer’s and Huntington’s disease; the PBT2 program was ended after a Phase 2 trial missed its primary endpoint.
Operates as a clinical-development enterprise rather than a commercial drug seller, with most staff in research and development. Its ordinary shares have an Australian primary listing while ADSs trade on Nasdaq, and its work is shaped by clinical execution, regulatory engagement, and financing milestones. No approved product is described in the latest reviewed filing.
Company facts
Target rangeAs of Sep 2, 2026
Latest analyst notes
| Date | Firm | Action | Rating | Prior target | Target |
|---|---|---|---|---|---|
| Aug 11, 2026 | UBS | Target | $12 | ||
| Aug 11, 2026 | Craig-Hallum | Initiate | Buy | $12 | $2 |
EPSReportedEstimate
RevenueReportedEstimate
Balance sheet, Jun 30, 2026Cash & short-term investments $26.8M · Total debt $139.0K · Total assets $33.1M · Shareholders' equity $30.7M
- Revenue
- $0
- Operating income
- −$11.2M
- Net income
- −$10.0M
Reported in AUD, converted at the latest exchange rate
No dividends on record.
| Institutions22 holders · as of Jun 30, 2026 | 2.33% | 394.5K ADS | |
| Insiders4 holders · as of Apr 15, 2026 | 1.00% | 170.1K ADS | |
| Otherremainder | 96.67% | 16.38M ADS |
16.94M ADS (1 ADS = 600 ordinary shares) as of Aug 23, 2026 · institutions as of Jun 30, 2026 · holders as of their latest filing
The share count is from the company's Jun 2024 annual report; nothing newer is on file here.
Top shareholders13F · 13D/G · Form 4
| Holder | Stake | Shares | Evidence |
|---|---|---|---|
David Allen StamlerInsiderdirector, officer: Chief Executive Officer | 0.94% | 11.69M ordinary · 139,258 ADS | Form 4filed Apr 15, 2026 ↗ |
Twin Lakes Capital Management, LLCInstitution | 0.82% | 139,258 ADS | 13Fas of Jun 30, 2026 |
Morgan StanleyInstitution | 0.37% | 63,065 ADS | 13Fas of Jun 30, 2026 |
Greenleaf TrustInstitution | 0.37% | 62,000 ADS | 13Fas of Jun 30, 2026 |
HB Wealth Management, LLCInstitution | 0.35% | 58,460 ADS | 13Fas of Jun 30, 2026 |
| See all 25 → | |||
13F — a manager's quarterly holdings · Form 4 — an insider's transaction report
Insider tradesForm 4
No open-market trades in the last 12 months.
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Compare
| Company | Price | Change | |||||
|---|---|---|---|---|---|---|---|
| Alterity Therapeutics (ADR) | $4.55 | 0.00% | $76.6M | — | — | — | −92.5% |
| Teva (ADR) | $37.45 | −0.05% | $43.66B | 62.5 | 13.3 | 2.4 | −0.8% |
| Ionis Pharmaceuticals | $60.74 | −0.93% | $10.19B | — | — | 11.7 | −40.7% |
| ProMIS Neurosciences | $14.21 | +6.44% | $18.3M | — | — | — | — |
| Median | 62.5 | 13.3 | 7.1 | −20.8% |