CMPX · NASDAQ · Biotechnology

Compass Therapeutics (CMPX)

Develops oncology antibody candidates for tumor microenvironment biology.

$2.46
Pre-market+0.02 (+1.03%)
At close$2.44(+5.41%)
Loading prices…

Compass Therapeutics, Inc.CMPXHealth Care

Develops oncology antibody candidates targeting angiogenesis and immune-system biology in the tumor microenvironment. Its clinical pipeline centers on tovecimig and three additional antibody programs.

Develops proprietary antibody therapeutics for oncology, focusing on angiogenesis and immune-system biology in the tumor microenvironment. Its clinical pipeline includes tovecimig, a DLL4 × VEGF-A bispecific antibody, alongside CTX-471, CTX-8371, and CTX-10726. These programs remain clinical candidates rather than currently marketed therapies.

Tovecimig is the lead candidate and is being studied in biliary tract and colorectal cancers. CTX-471 targets CD137/4-1BB, CTX-8371 targets PD-1 × PD-L1, and CTX-10726 targets PD-1 × VEGF-A. The company has no approved commercial products and depends on clinical development, manufacturing, and selected development or commercialization partners. Management may pursue selected strategic partners to develop or commercialize these programs.

Company facts

CEOThomas J. Schuetz
ListedNov 2, 2021
ExchangeNASDAQ
HeadquartersBoston, MA
CountryUnited States
Employees39
CIK0001738021
ISINUS20454B1044

Market cap$437.6M
EPS (ttm)−$0.4150
P/E (ttm)−5.86
ROE-38.7%
P/B2.73
P/S0.00
Dividend yieldDiv yield
Beta1.25vs XLV 0.81

Price target$7.50+208.6%Avg of 16 analysts
ConsensusBuy16 of 16 analysts
Ratings

Target rangeAs of Sep 2, 2026

Latest analyst notes

DateFirmActionPrior ratingRatingPrior targetTarget
Jun 1, 2026Stifel NicolausTarget$6
Mar 5, 2026JefferiesTarget$9
Feb 13, 2026Craig-HallumTarget$15
Feb 4, 2026Canaccord GenuityTarget$13
Jan 6, 2026Raymond JamesTarget$9

Next report
Nov 4, 2026
estimated · in 62 days
EPS estimate
−$0.12
Revenue estimate
$229.3K
Fiscal quarter
Q3 FY26

EPSReportedEstimate

Feb '25May '25Aug '25Nov '25Mar '26May '26Aug '26Nov '26
Reported−$0.11−$0.12−$0.14−$0.08−$0.09−$0.10−$0.13Pending
Estimate−$0.10−$0.12−$0.13−$0.14−$0.10−$0.10−$0.11−$0.12
Surprise−10.0%0.0%−7.7%+42.9%+10.0%0.0%−17.5%

RevenueReportedEstimate

Feb '25May '25Aug '25Nov '25Mar '26May '26Aug '26Nov '26
Reported$736.0KPending
Estimate−$900.0K−$818.2K−$600.0K$229.3K
Surprise+222.7%
Estimate−$0.12
ReportedDue Nov 4, 2026
Estimate$229.3K
ReportedDue Nov 4, 2026
View details

Debt to equity5.80%
Current ratio1,121.60%

ProfitabilityRevenueNet incomeNet margin

Q3 FY24Q4 FY24Q1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Revenue$0$0$0$0$0$0$0$0
Net income−$10.5M−$15.0M−$16.6M−$19.9M−$14.3M−$15.7M−$18.3M−$25.2M
Net margin

GrowthOperating income

Q3 FY24Q4 FY24Q1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Operating income−$12.2M−$16.6M−$18.0M−$21.1M−$15.8M−$18.0M−$20.3M−$27.0M
YoY growth

Balance sheet, Jun 30, 2026Cash & short-term investments $179.9M · Total debt $9.6M · Total assets $190.2M · Shareholders' equity $166.0M

Revenue
$0
Operating income
−$27.0M
Net income
−$25.2M
View details

No dividends on record.

Institutions209 holders · as of Mar 31, 2026 · largest filers plus last quarter's tail≈ 95.09%171.25M shares
Insiders3 holders · as of Apr 30, 20260.62%1.12M shares
Otherremainder≈ 4.29%7.72M shares

180.09M company shares as of Sep 3, 2026 · institutions as of Mar 31, 2026 · holders as of their latest filing

This quarter's institutional total failed a plausibility check; shown: the largest filers plus last quarter's remainder.

Top shareholders13F · 13D/G · Form 4

HolderStakeSharesEvidence
Tang Capital Management LLCInstitution
9.32%16.79M13Fas of Mar 31, 2026
Orbimed Advisors LLCInstitution
8.45%15.22M13Fas of Mar 31, 2026
Suvretta Capital Management, LLCInstitution
7.94%14.31M13Fas of Mar 31, 2026
Vivo Capital, LLCInstitution
5.30%9.55M13Fas of Mar 31, 2026
BlackRock, Inc.Institution
5.28%9.51M13Fas of Mar 31, 2026
See all 25

13F — a manager's quarterly holdings

Insider tradesForm 4

DateInsiderRoleSharesAvg price
Apr 29, 2026Jonathan Andermanofficer: General Counsel+25,000$1.89
Apr 29, 2026Neil Lernerofficer: Chief Accounting Officer+15,000$1.89
View details

  • Summit Therapeutics

    PD-1 × VEGF bispecific ivonescimab in late-stage solid-tumor trials

  • BioNTech (ADR)

    PD-L1 × VEGF-A bispecific pumitamig across solid-tumor trials

  • Merck

    Approved PD-1 therapy across NSCLC and triple-negative breast cancer

  • Bristol-Myers Squibb

    PD-1 inhibitor OPDIVO and co-development of a PD-L1 × VEGF-A bispecific

  • Agenus

    CD137 agonist AGEN2373 for solid tumors

ComparePre-market

CompanyPriceChange
Compass Therapeutics$2.46+1.03%$437.6M
Summit Therapeutics$15.26+4.52%$11.65B
BioNTech (ADR)$104.00+0.22%$26.08B8.5−60.7%
Merck$151.14−0.33%$374.52B121.317.65.6+5.1%
Bristol-Myers Squibb$67.38−0.40%$138.21B14.910.62.8+5.7%
Agenus$8.10+0.25%$336.9M3.12.5+34.3%
Median14.914.14.2+5.4%