Connect Biopharma (ADR) (CNTB)
Develops rademikibart for asthma and COPD outside Greater China.
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Develops rademikibart for asthma and COPD while other programs remain paused. Simcere holds Greater China rights, while Connect retains rights elsewhere.
Develops rademikibart, an anti-IL-4Rα antibody, as its lead candidate for asthma and COPD. The company concentrates its non-China effort on clinical development after pausing preclinical and discovery programs. It previously pursued a broader T-cell-inflammation pipeline.
Operations reflect San Diego headquarters and historical US–China development roots. Simcere holds exclusive Greater China rights to develop, manufacture and commercialize rademikibart, while Connect retains rights in the rest of the world. This arrangement divides development and commercialization responsibilities by region.
Near-term progress depends on pending Phase 2 Seabreeze STAT readouts in asthma and COPD. The drug candidate remains the company’s central program.
Company facts
Target rangeAs of Sep 2, 2026
Latest analyst notes
| Date | Firm | Action | Rating | Prior target | Target |
|---|---|---|---|---|---|
| Aug 14, 2026 | Canaccord Genuity | Target | $6 | $7 | |
| Jul 9, 2026 | Oppenheimer | Initiate | Outperform | $8 | |
| Jun 26, 2026 | Piper Sandler | Initiate | Overweight | $1.50 | $7 |
| Jun 18, 2026 | H.C. Wainwright | Target | $7 | ||
| May 26, 2026 | Canaccord Genuity | Target | $6 |
EPSReportedEstimate
RevenueReportedEstimate
Balance sheet, Jun 30, 2026Cash & short-term investments $31.5M · Total debt $596.0K · Total assets $43.5M · Shareholders' equity $26.9M
- Revenue
- $2.9M
- Operating income
- −$37.2M
- Net income
- −$36.7M
No dividends on record.
| Institutions46 holders · as of Mar 31, 2026 | 20.24% | 12.75M ADS | |
| Insiders9 holders · as of Jul 1, 2026 | 37.95% | 23.90M ADS | |
| Strategic holders3 holders · as of Apr 14, 2026 | 36.74% | 23.14M ADS | |
| Otherremainder | 5.07% | 3.20M ADS |
62.97M ADS as of Sep 3, 2026 · institutions as of Mar 31, 2026 · holders as of their latest filing
Top shareholders13F · 13D/G · Form 4
| Holder | Stake | Shares | Evidence |
|---|---|---|---|
Panacea Innovation LimitedStrategic | 22.15% | 13.95M | 13Dfiled Jul 21, 2025 ↗ |
James HuangInsiderdirector | 21.14% | 13.31M ordinary | Form 4filed Jun 2, 2026 ↗ |
Wubin PanInsider | 9.71% | 6.12M | 13Gfiled Feb 25, 2022 ↗ |
BioFortune IncStrategic | 9.51% | 5.99M | 13Gfiled Apr 14, 2026 ↗ |
Ikarian Capital, LLCInstitution | 8.56% | 5.39M ADS | 13Fas of Mar 31, 2026 |
| See all 25 → | |||
13F — a manager's quarterly holdings · 13D/13G — an ownership statement filed at 5% or more · Form 4 — an insider's transaction report
Insider tradesForm 4
| Date | Insider | Role | Shares | Avg price |
|---|---|---|---|---|
| May 29, 2026 | James Huang | director | +150,000 | $2.48 |
| Mar 31, 2026 | James Huang | director | +1,160,000 | $3.45 |
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ComparePre-market
| Company | Price | Change | |||||
|---|---|---|---|---|---|---|---|
| Connect Biopharma (ADR) | $2.80 | +1.27% | $173.8M | — | — | 59.2 | +40,914.3% |
| Regeneron | $850.48 | −0.18% | $87.78B | 21.1 | 14.1 | 5.7 | +16.7% |
| Sanofi (ADR) | $44.57 | +0.24% | $106.78B | 78.2 | — | 1.9 | +11.2% |
| GSK (ADR) | $50.65 | +0.45% | $101.06B | 15.8 | 9.1 | 2.2 | +2.7% |
| AstraZeneca (ADR) | $163.87 | +1.37% | $250.67B | 24.3 | 15.2 | 4.1 | +6.4% |
| Median | 22.7 | 14.1 | 3.2 | +8.8% |