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EQ · NASDAQ · Biotechnology

Equillium (EQ)

Develops EQ504, an investigational AhR modulator for ulcerative colitis and other inflammatory diseases.

$2.20

Pre-market−0.06 (−2.65%)

At close$2.26(+2.49%)

Watchlist

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Breakdown13F · 13D/G · Form 4

Institutions52 holders · as of Mar 31, 2026	63.87%	40.50M shares
Insiders3 holders · as of Jun 5, 2026	1.50%	951.2K shares
Strategic holders1 holder · as of May 15, 2026	6.74%	4.27M shares
Otherremainder	27.89%	17.69M shares

63.41M company shares as of Sep 3, 2026 · institutions as of Mar 31, 2026 · holders as of their latest filing

Top shareholders13F · 13D/G · Form 4

Holder	Stake	Shares	Evidence
Janus Henderson Group PLCInstitution	10.24%	6.49M	13Fas of Mar 31, 2026
Adage Capital Management, L.P.Institution	9.48%	6.01M	13Gfiled Nov 13, 2025 ↗
Adage Capital Partners GP, L.L.C.Institution	8.40%	5.33M	13Fas of Mar 31, 2026
Decheng Capital LLCInstitution	7.01%	4.45M	13Fas of Mar 31, 2026
Decheng Capital Management IV (Cayman), LLCStrategic	6.74%	4.27M	13Gfiled May 15, 2026 ↗
Adar1 Capital Management, LLCInstitution	5.88%	3.73M	13Fas of Mar 31, 2026
Woodline Partners LPInstitution	5.52%	3.50M	13Fas of Mar 31, 2026
Abrdn PLCInstitution	5.29%	3.35M	13Fas of Mar 31, 2026
Ra Capital Management, L.P.Institution	4.88%	3.10M	13Fas of Mar 31, 2026
Vanguard Capital Management LLCInstitution	2.81%	1.78M	13Fas of Mar 31, 2026
Balyasny Asset Management L.P.Institution	2.58%	1.64M	13Fas of Mar 31, 2026
Eversept Partners, LPInstitution	2.36%	1.50M	13Fas of Mar 31, 2026
Affinity Asset Advisors, LLCInstitution	1.93%	1.23M	13Fas of Mar 31, 2026
Stephen ConnellyInsiderofficer: President and CSO	1.20%	762,025	Form 4filed Jun 5, 2026 ↗
Renaissance Technologies LLCInstitution	1.04%	656,964	13Fas of Mar 31, 2026
Diadema Partners LPInstitution	0.68%	433,844	13Fas of Mar 31, 2026
Hudson Bay Capital Management LPInstitution	0.68%	428,538	13Fas of Mar 31, 2026
Geode Capital Management, LLCInstitution	0.60%	378,813	13Fas of Mar 31, 2026
Ikarian Capital, LLCInstitution	0.48%	303,555	13Fas of Mar 31, 2026
Cantor Fitzgerald, L. P.Institution	0.41%	262,643	13Fas of Mar 31, 2026
Two Sigma Investments, LPInstitution	0.39%	246,173	13Fas of Mar 31, 2026
Jane Street Group, LLCInstitution	0.35%	221,241	13Fas of Mar 31, 2026
Vanguard Fiduciary Trust CoInstitution	0.30%	189,530	13Fas of Mar 31, 2026
State Street CorpInstitution	0.27%	174,060	13Fas of Mar 31, 2026
Citadel Advisors LLCInstitution	0.25%	158,733	13Fas of Mar 31, 2026

13F — a manager's quarterly holdings · 13D/13G — an ownership statement filed at 5% or more · Form 4 — an insider's transaction report

Institutions13F, as of Mar 31, 2026

52 holders · 40.50M shares · 18 new positions · 28 increased · 11 reduced · 6 closed

Holder	Shares	% outstanding	Chg q/q	Filed
Janus Henderson Group PLC	6.49M	10.24%	+632.4K	May 18, 2026
Adage Capital Partners GP, L.L.C.	5.33M	8.40%	0	May 15, 2026
Decheng Capital LLC	4.45M	7.01%	0	May 13, 2026
Adar1 Capital Management, LLC	3.73M	5.88%	−1.88M	May 18, 2026
Woodline Partners LP	3.50M	5.52%	0	May 15, 2026
Abrdn PLC	3.35M	5.29%	+986.1K	Apr 29, 2026
Ra Capital Management, L.P.	3.10M	4.88%	+3.10Mnew	May 15, 2026
Vanguard Capital Management LLC	1.78M	2.81%	+1.78Mnew	May 15, 2026

Ownership statements13D/G · 5% or more, as filed

Holder	% of class	Shares	Form	Filed
Janus Henderson Group PLC	9.99%	6.08M	13G	Feb 6, 2026 ↗
Adage Capital Management, L.P.	9.99%	6.01M	13G	Nov 13, 2025 ↗
ADAR1 Capital Management, LLC	9.90%	6.60M	13G	May 15, 2026 ↗
RA Capital Management, L.P.	9.90%	6.48M	13G	Mar 20, 2026 ↗
Decheng Capital Management IV (Cayman), LLC	6.70%	4.27M	13G	May 15, 2026 ↗
Affinity Asset Advisors, LLC	6.50%	4.10M	13G	Aug 13, 2026 ↗
Woodline Partners LP	5.90%	3.51M	13G	Nov 14, 2025 ↗
Aberdeen Group plc	5.30%	3.35M	13G	May 7, 2026 ↗

Insider tradesForm 4

Latest trades

Date	Insider	Type	Shares	Avg price	Owned after
Jun 5, 2026	Stephen Connellyofficer: President and CSO	Sale	30,975	$2.94	762,025
Jun 4, 2026	Stephen Connellyofficer: President and CSO	Sale	200,000	$3.16	793,000
Jun 5, 2026	Christine Zedelmayerofficer: Sr. Vice President and COO	Sale	14,584	$2.93	62,586
May 27, 2026	Christine Zedelmayerofficer: Sr. Vice President and COO	Sale	9,821	$2.70	62,586
May 28, 2026	Christine Zedelmayerofficer: Sr. Vice President and COO	Sale · 3 lots	86,012	$2.80	62,586
May 28, 2026	Penny Tomofficer: Principal Accounting Officer	Sale	65,000	$2.95	0
Mar 13, 2026	Christine Zedelmayerofficer: Sr. Vice President and COO	Sale	120,312	$2.50	62,586
Mar 9, 2026	Christine Zedelmayerofficer: Sr. Vice President and COO	Sale	181,219	$2.00	62,586
Feb 19, 2026	Christine Zedelmayerofficer: Sr. Vice President and COO	Sale · 2 lots	185,937	$1.76	91,444
Jan 8, 2026	Penny Tomofficer: Principal Accounting Officer	Sale	6,533	$1.29	0

CongressHouse and Senate disclosures

Not reported.