EYPT · NASDAQ · Biotechnology

EyePoint

Develops sustained-release retinal therapies built around DURAVYU and Durasert E technology.

$4.51
After-hours close+0.03 (+0.74%)
At close$4.48(−3.35%)
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Profile

EyePoint Pharmaceuticals, Inc.EYPTHealth Care

Develops sustained-release retinal therapies for wet AMD and diabetic macular edema, with DURAVYU as the central late-stage program. Operations are U.S.-based and centered on Durasert E drug delivery, a Massachusetts manufacturing base, and legacy YUTIQ economics rather than a broad commercial product portfolio.

Develops ophthalmic products for serious retinal diseases, led by DURAVYU, an investigational sustained-release vorolanib insert built on Durasert E. Current work centers on wet AMD and diabetic macular edema, with EYP-2301 adding an earlier retinal-disease program using the same delivery platform.

Operations are concentrated in the United States, with headquarters and research in Watertown, Massachusetts, and a Northbridge facility built to support DURAVYU manufacturing if approved. The business reports one segment, so pipeline programs and legacy economics define the operating picture more than formal segment lines.

Execution depends on pivotal trial results, regulatory review, manufacturing readiness, and launch preparation for DURAVYU. YUTIQ is no longer the main commercial asset, but prior rights sales and royalty arrangements remain economically relevant.

Company facts

CEOJay S. Duker, M.D.
ListedJun 11, 2008
ExchangeNASDAQ
HeadquartersWatertown, MA
CountryUnited States
Employees214
CIK0001314102
ISINUS30233G2093

Key statistics

Market cap$375.6M
EPS (ttm)−$3.74
P/E (ttm)−1.20
ROE-135.8%
P/B2.33
P/S134.68
Dividend yield
Beta1.09vs XLV 0.70

Year to date −74.4% · Average volume (30d) 5.0M

Analysts

Price target, next 12 months$17.50+290.6%Median of 19 analysts · vs the Aug 28 close
ConsensusBuy13 of 19 analysts rate it buy or better

Ratings

Target range

Latest analyst notes

DateFirmActionPrior ratingRatingPrior targetTarget
Aug 18, 2026Chardan CapitalDowngradeBuyNeutral$5
Aug 18, 2026H.C. WainwrightDowngradeBuyNeutral
Aug 18, 2026HC Wainwright & Co.DowngradeBuyNeutral
Aug 18, 2026RBC CapitalDowngradeOutperformSector Perform
Aug 17, 2026RBC CapitalDowngradeOutperformSector Perform$39$5

Earnings

EPS

Estimate−$0.91
ReportedDue Nov 4, 2026

Revenue

Estimate$232.2K
ReportedDue Nov 4, 2026

History

Report dateEPS estEPSSurpriseRevenue estRevenueSurpriseNext session
Aug 5, 2026Q2 FY26−$1.01−$1.09−7.9%$451.2K$507.0K+12.4%+4.97%
May 6, 2026Q1 FY26−$0.79−$0.99−25.3%$352.8K$696.0K+97.3%+0.45%
Mar 4, 2026Q4 FY25−$0.78−$0.81−3.8%$994.5K$620.0K−37.7%−12.44%
Nov 5, 2025Q3 FY25−$0.77−$0.85−10.4%$1.0M$966.0K−4.0%+0.54%
View details

Financial highlights

12 quartersQ1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Revenue$24.5M$5.3M$966.0K$620.0K$696.0K$507.0K
Gross profit$23.6M$5.2M$245.0K$245.0K$168.0K$507.0K
Operating income−$48.8M−$62.2M−$62.0M−$70.3M−$87.2M−$97.4M
Net income−$45.2M−$59.4M−$59.7M−$67.6M−$84.8M−$94.5M
Diluted EPS−$0.65−$0.85−$0.85−$0.81−$0.99−$1.09
Gross margin96.7%96.9%25.4%39.5%24.1%100.0%
Operating margin-199.7%-1,166.8%-6,420.8%-11,346.0%-12,532.5%-19,207.1%

Fiscal years (4-quarter sums)FY21 $36.9M · FY22 $41.4M · FY23 $46.0M · FY24 $43.3M · FY25 $31.4M

Revenue by product · FY24

License And Collaboration Agreement$38.5M · 83%
Product$3.2M · 7%
Y U T I Q Product$3.1M · 7%
Royalty$1.6M · 3%

Revenue by geography · FY24

United States$42.0M · 97%
China$1.1M · 3%

Balance sheet, Jun 30, 2026Cash & short-term investments $180.5M · Total debt $22.4M · Total assets $228.2M · Shareholders' equity $166.4M

Dividends

No dividends on record.

Ownership

Institutions 113.12%Insiders 0.81%

A 13F quarter can total more than the shares outstanding — sub-advisers file the same block twice, and a filer's own share count can be a quarter stale. No split is drawn from it.

Shares outstanding 83.84M · Float 70.47M · 84.1% free float

Top shareholders13F · 13D/G · Form 4

HolderShares% outstandingFormFiled
Suvretta Capital Management, LLC8.30M9.90%13FAug 14, 2026
BlackRock, Inc.7.46M8.90%13FAug 7, 2026
Cormorant Asset Management, LP7.00M8.35%13FAug 14, 2026
Federated Hermes, Inc.5.68M6.78%13FAug 12, 2026
Adage Capital Partners GP, L.L.C.4.83M5.76%13FAug 14, 2026

Insider tradesForm 4

DateInsiderRoleSharesAvg price
Aug 18, 2026Karen L. Zaderejdirector+10,600$4.93
Jun 30, 2026Ramiro Ribeiroofficer: Chief Medical Officer−4,875$15.01
Apr 17, 2026Ramiro Ribeiroofficer: Chief Medical Officer−2,437$15.00
Mar 16, 2026Jay S. Dukerdirector, officer: President and CEO+1,500$13.15
Mar 4, 2026Ramiro Ribeiroofficer: Chief Medical Officer−2,438$17.87
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Peers

  • Regeneron

    Dominant aflibercept incumbent in wet AMD and DME

  • Ocular Therapeutix

    Phase 3 axitinib implant peer for durable wet AMD therapy

  • Novartis (ADR)

    Approved anti-VEGF rival through Beovu in wet AMD and DME

  • Harrow

    U.S. anti-VEGF biosimilar marketer through BYOOVIZ and OPUVIZ

  • Alcon

    Global eye-care player developing AR-14034 for wet AMD

CompareAfter-hours close

CompanyPriceChange
EyePoint$4.51+0.74%$375.6M134.7−90.5%
Regeneron$793.21−0.11%$81.82B19.613.15.3+16.7%
Ocular Therapeutix$10.45+0.87%$2.27B43.6+0.1%
Novartis (ADR)$153.810.00%$292.35B23.216.45.3+0.9%
Harrow$37.77+1.29%$1.39B30.35.0+10.9%
Alcon$72.15+0.21%$35.12B55.418.63.3+7.5%
Median23.217.55.3+7.5%