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GTBP · NASDAQ · Biotechnology

GT Biopharma (GTBP)

Developer of natural-killer-cell engagers for cancer and autoimmune disease.

$0.2833
At close−0.01 (−1.94%)
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GT Biopharma, Inc.GTBPHealth Care

Develops TriKE fusion proteins that activate natural killer cells against cancer targets, with a preclinical autoimmune program. The asset-light business has no approved products or revenue and depends on University of Minnesota licenses, external development partners, and additional funding.

Develops TriKE and Dual Targeting TriKE fusion proteins that connect natural killer cells to cancer-cell antigens while supplying an IL-15 signal. The active pipeline includes GTB-3650 for acute myeloid leukemia and high-risk myelodysplastic syndrome, GTB-5550 for advanced solid tumors, and GTB-7550, a preclinical CD19 program for lupus and other autoimmune disorders.

Operates as a virtual, asset-light biopharmaceutical business with worldwide licensed rights from the University of Minnesota and clinical execution centered in the United States. No approved products or product revenue support the business; development relies on the university, consultants, research institutions, contract manufacturers, and external funding.

Company facts

CEOMichael Breen
ListedFeb 11, 2021
ExchangeNASDAQ
HeadquartersSan Francisco, CA
CountryUnited States
Employees1
CIK0000109657
ISINUS36254L3087

Market cap$8.9M
EPS (ttm)−$4.16
P/E (ttm)−0.0680
ROE-443.1%
P/B3.08
P/S0.00
Dividend yieldDiv yield
Beta1.96vs XLV 0.02

No analyst consensus on record.

Next report
Nov 13, 2026
in 71 days
EPS estimate
−$0.10
Revenue estimate
Fiscal quarter
Q3 FY26

EPSReportedEstimate

Feb '25May '25Aug '25Nov '25Mar '26May '26Aug '26Nov '26
Reported−$1.66−$0.76−$0.55−$0.83−$2.22−$0.11−$0.12Pending
Estimate−$1.55−$0.64−$0.68−$0.38−$0.22−$0.08−$0.08−$0.10
Surprise−7.1%−18.8%+19.1%−118.4%−909.1%−37.5%−50.0%

RevenueReportedEstimate

Feb '25May '25Aug '25Nov '25Mar '26May '26Aug '26Nov '26
ReportedPending
Estimate
Surprise
Estimate−$0.10
ReportedDue Nov 13, 2026
Estimate
ReportedDue Nov 13, 2026
View details

Debt to equity0.00%
Current ratio260.80%

ProfitabilityRevenueNet incomeNet margin

Q3 FY24Q4 FY24Q1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Revenue$0$0$0$0$0$0$0$0
Net income−$3.4M−$3.8M−$776.0K−$30.2M$8.3M−$23.0M−$2.8M−$4.5M
Net margin

GrowthOperating income

Q3 FY24Q4 FY24Q1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Operating income−$3.6M−$3.8M−$1.9M−$1.5M−$3.4M−$5.6M−$2.8M−$4.5M
YoY growth

Balance sheet, Jun 30, 2026Cash & short-term investments $5.0M · Total debt $0 · Total assets $5.8M · Shareholders' equity $3.6M

Revenue
$0
Operating income
−$4.5M
Net income
−$4.5M
View details

No dividends on record.

Institutions58 holders · as of Jun 30, 20264.70%2.12M shares
Insiders1 holder · as of Feb 5, 20190.02%9.2K shares
Strategic holders2 holders · as of Dec 4, 20170.02%7.3K shares
Otherremainder95.26%42.97M shares

45.11M company shares as of Sep 3, 2026 · institutions as of Jun 30, 2026 · holders as of their latest filing

Two share counts disagree (45.11M in the company's Sep 3, 2026 report, 31.55M elsewhere); stakes use the report.

Top shareholders13F · 13D/G · Form 4

HolderStakeSharesEvidence
Vanguard Capital Management LLCInstitution
0.83%376,39913Fas of Jun 30, 2026
Geode Capital Management, LLCInstitution
0.59%266,78813Fas of Jun 30, 2026
Vanguard Fiduciary Trust CoInstitution
0.50%225,93813Fas of Jun 30, 2026
HRT Financial LPInstitution
0.24%107,14013Fas of Jun 30, 2026
Everhart Financial Group, Inc.Institution
0.22%100,00013Fas of Jun 30, 2026
See all 25

13F — a manager's quarterly holdings

Insider tradesForm 4

No open-market trades in the last 12 months.

View details

  • Innate Pharma (ADR)

    Closest NK-cell-engager platform across myeloid and B7-H3 programs.

  • Pfizer

    Approved CD33 therapy sets a direct AML treatment benchmark.

  • Merck

    Global co-developer of a leading B7-H3 solid-tumor ADC.

  • Cabaletta Bio

    Clinical CD19 CAR-T program pursues deep B-cell depletion in lupus.

  • Kyverna Therapeutics

    Later-stage CD19 CAR-T program targets B-cell-driven autoimmunity.

Compare

CompanyPriceChange
GT Biopharma$0.2833−1.94%$8.9M
Innate Pharma (ADR)$2.17+2.36%$203.8M60.6+1,574.1%
Pfizer$28.99−0.14%$165.40B38.310.42.6+2.6%
Merck$151.72+0.05%$374.52B121.317.65.6+5.1%
Cabaletta Bio$3.58+0.14%$582.1M
Kyverna Therapeutics$8.62+3.17%$523.8M
Median79.814.05.6+5.1%