INmune Bio (INMB)
Develops innate-immunity therapies for rare disease, Alzheimer’s disease and cancer.
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Develops CORDStrom-derived Ebstrocel for RDEB, soluble-TNF inhibitor XPro for inflammation-selected Alzheimer’s disease, and NK-cell therapy INKmune for cancer. The clinical-stage pipeline operates as one segment and depends on licensed data and technology, external supply and manufacturing partners, regulatory approvals, and additional capital.
Develops therapies that modify innate-immune dysfunction across rare disease, neuroinflammation and cancer. CORDStrom-derived Ebstrocel, a pooled umbilical-cord stromal-cell candidate for RDEB, is the lead program and is moving toward planned UK, EU and US regulatory submissions.
XPro targets inflammation-selected early Alzheimer’s disease, while INKmune primes a patient’s natural-killer cells against residual cancer. Later XPro development requires a strategic partner, and INKmune is not being advanced under the current capital plan.
Operations span the United States and United Kingdom, with most employees based in the UK. The business relies on licensed MissionEB data and platform rights, third-party cord-tissue supply and manufacturing, regulatory acceptance, and continued financing. None of its named candidates is approved.
Company facts
Target rangeAs of Sep 2, 2026
Latest analyst notes
| Date | Firm | Action | Prior rating | Rating |
|---|---|---|---|---|
| Mar 11, 2026 | LUCID CAPITAL MARKETS | Upgrade | Neutral | Buy |
| Jul 1, 2025 | BTIG | Downgrade | Buy | Neutral |
| Jul 1, 2025 | Scotiabank | Downgrade | Sector Outperform | Sector Underperform |
EPSReportedEstimate
RevenueReportedEstimate
Balance sheet, Jun 30, 2026Cash & short-term investments $18.4M · Total debt $1.4M · Total assets $26.8M · Shareholders' equity $20.4M
- Revenue
- $0
- Operating income
- −$1.5M
- Net income
- −$1.3M
No dividends on record.
| Institutions86 holders · as of Mar 31, 2026 | 19.37% | 5.38M shares | |
| Insiders4 holders · as of Jul 7, 2026 | 16.05% | 4.45M shares | |
| Strategic holders1 holder · as of Aug 14, 2025 | 5.24% | 1.45M shares | |
| Otherremainder | 59.34% | 16.47M shares |
27.75M company shares as of Sep 3, 2026 · institutions as of Mar 31, 2026 · holders as of their latest filing
Top shareholders13F · 13D/G · Form 4
| Holder | Stake | Shares | Evidence |
|---|---|---|---|
Raymond Joseph TesiInsiderdirector, 10 percent owner, officer: President and CEO | 5.60% | 1.55M | Form 4filed Sep 16, 2024 ↗ |
Mark William LowdellInsiderofficer: Chief Scientific Officer | 5.47% | 1.52M | Form 4filed Jul 7, 2026 ↗ |
Highbridge Capital Management, LLCStrategic | 5.24% | 1.45M | 13Gfiled Aug 14, 2025 ↗ |
David J. MossInsiderdirector, officer: Chief Executive Officer | 4.67% | 1.29M | Form 4filed Jul 7, 2026 ↗ |
BlackRock, Inc.Institution | 4.30% | 1.19M | 13Fas of Mar 31, 2026 |
| See all 25 → | |||
13F — a manager's quarterly holdings · 13D/13G — an ownership statement filed at 5% or more · Form 4 — an insider's transaction report
Insider tradesForm 4
No open-market trades in the last 12 months.
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ComparePre-market
| Company | Price | Change | |||||
|---|---|---|---|---|---|---|---|
| INmune Bio | $2.43 | +2.97% | $62.5M | — | — | — | — |
| Krystal Biotech | $375.00 | +1.53% | $10.88B | 46.3 | 43.5 | 24.7 | +24.1% |
| Abeona Therapeutics | $5.86 | −1.76% | $339.1M | — | — | 13.3 | +2,745.0% |
| Eli Lilly | $1,167.77 | +0.72% | $1.09T | 38.9 | 28.4 | 13.7 | +47.7% |
| Biogen | $222.65 | −0.03% | $32.90B | 39.4 | 16.8 | 3.3 | +3.4% |
| BioVie | $2.02 | 0.00% | $15.3M | — | — | — | — |
| GT Biopharma | $0.2833 | −1.94% | $8.9M | — | — | — | — |
| Median | 39.4 | 28.4 | 13.5 | +35.9% |