MIST · NASDAQ · Biotechnology

Milestone Pharmaceuticals (MIST)

Commercializes an etripamil nasal spray for acute adult PSVT episodes.

$1.18
Pre-market+0.00 (+0.34%)
At close$1.18(+3.51%)

Breakdown13F · 13D/G · Form 4

Institutions86 holders · as of Jun 30, 2026 · largest filers plus last quarter's tail≈ 11.73%14.61M shares
Insiders8 holders · as of Apr 20, 20260.88%1.10M shares
Strategic holders1 holder · as of May 15, 20269.93%12.36M shares
Otherremainder≈ 77.46%96.44M shares

124.50M company shares as of Sep 3, 2026 · institutions as of Jun 30, 2026 · holders as of their latest filing

This quarter's institutional total failed a plausibility check; shown: the largest filers plus last quarter's remainder.

Top shareholders13F · 13D/G · Form 4

HolderStakeSharesEvidence
RTW Investments, LP1Strategic10 percent owner
9.93%12.36M13Gfiled May 15, 2026
Pavaki Capital Management LLCInstitution
7.28%9.07M13Fas of Jun 30, 2026
Adage Capital Management, L.P.Institution
6.43%8.00M13Gfiled May 13, 2026
Two Sigma Investments, LPInstitution
1.64%2.04M13Fas of Jun 30, 2026
Marshall Wace, LLPInstitution
1.44%1.80M13Fas of Jun 30, 2026
Ameriprise Financial IncInstitution
0.54%666,66613Fas of Jun 30, 2026
Joseph OlivetoInsiderdirector, officer: President and CEO
0.36%446,244Form 4filed Apr 20, 2026
Susquehanna International Group, LLPInstitution
0.29%359,89513Fas of Jun 30, 2026
Guardian Wealth Advisors, LLC / NCInstitution
0.27%339,45013Fas of Jun 30, 2026
LPL Financial LLCInstitution
0.18%220,87313Fas of Jun 30, 2026
Lorenz MullerInsiderofficer: Chief Commercial Officer
0.16%205,406Form 4filed Jan 28, 2026
David BharuchaInsiderofficer: Chief Medical Officer
0.09%113,181Form 4filed Jan 28, 2026
Joseph C. PapaInsiderdirector
0.08%100,000Form 4filed Jul 15, 2025
Amit HasijaInsiderofficer: CFO & EVP of Corp. Development
0.08%99,848Form 4filed Jan 28, 2026
Robert James WillsInsiderdirector
0.05%65,000Form 4filed Jul 15, 2025
Jeffrey Edward NelsonInsiderofficer: Chief Operating Officer
0.04%49,848Form 4filed Jan 28, 2026
Geode Capital Management, LLCInstitution
0.03%40,78913Fas of Jun 30, 2026
Mariner, LLCInstitution
0.02%27,83013Fas of Jun 30, 2026
Debra K. LiebertInsiderdirector
0.01%16,793Form 4filed Jul 15, 2025
Jones Financial Companies LLLPInstitution
0.01%16,00013Fas of Jun 30, 2026
Pathstone Holdings, LLCInstitution
0.01%15,50013Fas of Jun 30, 2026
Safeguard Investment Advisory Group, LLCInstitution
0.01%12,40613Fas of Jun 30, 2026
Mercer Global Advisors Inc /AdvInstitution
0.00%12313Fas of Jun 30, 2026
Alta Fundamental Advisers LLCStrategic
5.00% of class, as filed13Dfiled Nov 9, 2023
Domain Partners VIII, L.P.Institution
2.90% of class, as filed13G/Afiled Jan 21, 2021
  1. RTW Investments, LP's transaction reports restate only vehicles that traded; the 2026 ownership statement (12.36M) is used instead.

13F — a manager's quarterly holdings · 13D/13G — an ownership statement filed at 5% or more · Form 4 — an insider's transaction report

Institutions13F, as of Jun 30, 2026

86 holders · 14.61M shares · 7 new positions · 30 increased · 23 reduced · 15 closed

HolderShares% outstandingChg q/qFiled
Pavaki Capital Management LLC9.07M7.28%+5.0KAug 7, 2026
Two Sigma Investments, LP2.04M1.64%−277.2KAug 14, 2026
Marshall Wace, LLP1.80M1.44%−146.8KAug 13, 2026
Ameriprise Financial Inc666.7K0.54%0Aug 14, 2026
Susquehanna International Group, LLP359.9K0.29%−159.2KAug 14, 2026
Guardian Wealth Advisors, LLC / NC339.5K0.27%+59.2KAug 14, 2026
LPL Financial LLC220.9K0.18%+27.5KAug 7, 2026
Geode Capital Management, LLC40.8K0.03%0Aug 12, 2026

Ownership statements13D/G · 5% or more, as filed

Holder% of classSharesFormFiled
RTW Investments, LP9.90%12.36M13GMay 15, 2026
Propel Bio Management, LLC9.90%8.86M13GDec 23, 2025
Pavaki Capital Management LLC7.30%9.07M13GAug 7, 2026
Adage Capital Management, L.P.6.37%8.00M13GMay 13, 2026

Insider tradesForm 4

Latest trades

DateInsiderTypeSharesAvg priceOwned after
Apr 16, 2026
Joseph Olivetodirector, officer: President and CEO
Sale36,500$2.26446,244
Dec 15, 2025
Joseph Olivetodirector, officer: President and CEO
Sale133,054$2.32450,667
Jan 26, 2026
Joseph Olivetodirector, officer: President and CEO
Sale34,523$1.93482,744
Dec 15, 2025
Amit Hasijaofficer: CFO & EVP of Corp. Development
Sale58,007$2.3291,993
Jan 26, 2026
Amit Hasijaofficer: CFO & EVP of Corp. Development
Sale12,245$1.9399,848
Dec 15, 2025
Lorenz Mullerofficer: Chief Commercial Officer
Sale53,566$2.32196,486
Jan 26, 2026
Lorenz Mullerofficer: Chief Commercial Officer
Sale11,180$1.93205,406
Dec 15, 2025
Jeffrey Edward Nelsonofficer: Chief Operating Officer
Sale58,007$2.3241,993
Jan 26, 2026
Jeffrey Edward Nelsonofficer: Chief Operating Officer
Sale12,245$1.9349,848
Dec 15, 2025
David Bharuchaofficer: Chief Medical Officer
Sale58,007$2.32105,326

CongressHouse and Senate disclosures

Not reported.