ONC · NASDAQ · Biotechnology

BeOne Medicines (ADR)

Develops and commercializes oncology medicines through an in-house global model.

$366.73
After-hours close−0.03 (−0.01%)
At close$366.76(−1.54%)
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Profile

BeOne Medicines Ltd.ONCHealth Care

Discovers, develops, manufactures, and commercializes oncology medicines, led by BRUKINSA and TEVIMBRA. A global in-house model connects blood-cancer and solid-tumor research with commercialization, while the business depends on country-specific approvals, reimbursement, intellectual property, manufacturing execution, and a small number of products.

Develops and commercializes oncology medicines through an in-house model spanning research, clinical development, manufacturing, and commercialization. BRUKINSA, a BTK inhibitor, is the commercial anchor; TEVIMBRA, an anti-PD-1 antibody, adds a second major proprietary franchise, alongside PARTRUVIX and in-licensed products such as XGEVA, BLINCYTO, and KYPROLIS.

Operates through major hubs in Basel, Beijing, Cambridge, San Carlos, and Hopewell, with products approved across many markets and research programs covering blood cancers and solid tumors. Founder-led continuity and control from discovery through commercialization define the operating model.

Depends on country-specific approvals, reimbursement, intellectual-property protection, manufacturing execution, and a small number of commercial products. Patent disputes involving BRUKINSA and shifting partnership rights around TEVIMBRA also shape the commercial perimeter.

Company facts

CEOJohn V. Oyler
ListedFeb 3, 2016
ExchangeNASDAQ
HeadquartersBasel, Switzerland
CountryUnited States
Employees11,785
CIK0001651308
ISINUS07725L1026

Key statistics

Market cap$39.19B
EPS (ttm)$72.28
P/E (ttm)5.07
ROE14.3%
P/B11.33
P/S6.86
Dividend yield
Beta0.77vs XLV 0.70

Year to date +17.9% · Average volume (30d) 373.7K

Analysts

Price target, next 12 months$400.00+9.1%Median of 14 analysts · vs the Aug 28 close
ConsensusBuy14 of 14 analysts rate it buy or better

Ratings

Target range

Latest analyst notes

DateFirmActionPrior ratingRatingPrior targetTarget
Aug 10, 2026Wolfe ResearchReiterateOutperform$340$370
Aug 6, 2026BarclaysReiterateOverweight$403$407
Jul 14, 2026BarclaysReiterateOverweight$409$403
Jul 13, 2026JefferiesUpgradeBuyPositive
Jul 12, 2026JefferiesReiterateBuy$420$380

Earnings

EPS

Estimate$1.90
ReportedDue Nov 5, 2026

Revenue

Estimate$1.75B
ReportedDue Nov 5, 2026

History

Report dateEPS estEPSSurpriseRevenue estRevenueSurpriseNext session
Aug 5, 2026Q2 FY26$1.63$2.05+25.8%$1.62B$1.71B+4.9%+1.40%
May 6, 2026Q1 FY26$0.73$1.96+168.5%$1.48B$1.51B+2.5%+1.17%
Feb 26, 2026Q4 FY25$1.60$0.58−63.7%$1.47B$1.50B+2.2%−1.67%
Nov 6, 2025Q3 FY25$0.72$1.09+51.4%$1.45B$1.41B−2.7%−3.73%
View details

Financial highlights

12 quartersQ1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Revenue$1.12B$1.32B$1.41B$1.50B$1.51B$1.71B
Gross profit$952.3M$1.15B$1.22B$1.36B$1.35B$1.53B
Operating income$11.1M$87.9M$163.1M$185.0M$249.9M$325.0M
Net income$1.3M$94.3M$124.8M$66.5M$227.4M$237.0M
Diluted EPS$0.01$0.84$13.52$6.76$25.35$26.65
Gross margin85.2%87.5%86.1%90.5%89.0%89.8%
Operating margin1.0%6.7%11.5%12.4%16.5%19.1%

Fiscal years (4-quarter sums)FY21 $1.18B · FY22 $1.42B · FY23 $2.46B · FY24 $3.81B · FY25 $5.34B

Revenue by product · Q2 FY26

Product$2.21B · 100%

Revenue by geography · Q2 FY26

United States$914.2M · 54%
China$506.0M · 30%
Europe$208.8M · 12%
All Other Countries Except China And United States Of America$76.1M · 4%

Balance sheet, Jun 30, 2026Cash & short-term investments $5.10B · Total debt $1.14B · Total assets $9.18B · Shareholders' equity $5.17B

Dividends

No dividends on record.

Ownership

Institutions 32.73%Insiders

Shares outstanding 106.86M · Float 67.18M · 62.9% free float

Insiders — filings are in the shares behind the receipt.

This listing is a depositary receipt and the Form 4 positions here are filed in the shares behind it, a different unit from the share count and in a ratio the filings never state, so no insider percentage is shown.

Top shareholders13F · 13D/G · Form 4

HolderShares% outstandingFormFiled
Baker Bros. Advisors LP8.80M8.24%13FAug 14, 2026
Primecap Management Co/CA/5.01M4.69%13FAug 14, 2026
Capital International Investors4.21M3.94%13FAug 12, 2026
FMR LLC2.48M2.32%13FAug 13, 2026
Capital World Investors2.25M2.11%13FAug 12, 2026

Insider tradesForm 4

DateInsiderRoleSharesAvg price
Aug 25, 2026Xiaobin Wuofficer: President and COO−280$380.00
Aug 11, 2026Chan Henry Leeofficer: SVP, General Counsel−2,666$360.00
Aug 12, 2026John Oylerdirector, officer: Chief Executive Officer−54,892$358.15
Aug 11, 2026John Oylerdirector, officer: Chief Executive Officer−70,907$361.90
Aug 10, 2026John Oylerdirector, officer: Chief Executive Officer−115,011$357.87
View details

Peers

  • AstraZeneca (ADR)

    Closest global BTK-class rival across major B-cell malignancies

  • AbbVie

    Direct BTK rivalry through jointly marketed IMBRUVICA

  • Merck

    Global PD-1 benchmark across overlapping solid tumors

  • Eli Lilly

    Non-covalent BTK challenger in relapsed blood cancers

  • Bristol-Myers Squibb

    PD-1 rival in upper gastrointestinal cancers

CompareAfter-hours close

CompanyPriceChange
BeOne Medicines (ADR)$366.73−0.01%$39.19B5.146.76.9+29.6%
AstraZeneca (ADR)$161.79−0.55%$252.33B24.415.24.1+6.4%
AbbVie$255.80+0.13%$451.38B72.016.87.0+10.2%
Merck$148.19−0.08%$366.18B118.717.25.5+5.1%
Eli Lilly$1,173.00−0.08%$1.10T39.428.713.9+47.7%
Bristol-Myers Squibb$66.60+0.05%$136.00B14.710.52.8+5.7%
Median39.416.85.5+6.4%