SLN · NASDAQ · Biotechnology

Silence Therapeutics (ADR)

Develops liver-targeted siRNA medicines through its mRNAi GOLD platform.

$13.42
After-hours close−0.04 (−0.30%)
At close$13.46(+0.07%)

Breakdown13F · Form 4

Institutions 42.15%Insiders

Shares outstanding 47.23M · Float 37.67M · 79.8% free float

Insiders — filings are in the shares behind the receipt.

A Form 4 total here can count shares the filer formally disclaims — an award voted by proxy, for instance — which the holder's own Schedule 13D/G excludes, so where the two disagree the schedule's smaller figure is used.

This listing is a depositary receipt and the Form 4 positions here are filed in the shares behind it, a different unit from the share count and in a ratio the filings never state, so no insider percentage is shown.

Top shareholders13F · 13D/G · Form 4

HolderShares% outstandingFormFiled
Richard Ian Griffiths34.54M24.40%13DJun 25, 2025
Richard Griffiths14.39M7.97%13DAug 13, 2026
TCG Crossover Management, LLC3.03M6.42%13FMay 15, 2026
Siren, L.L.C.2.91M6.16%13FMay 14, 2026
Redmile Group, LLC2.16M4.58%13FMay 15, 2026

Institutions13F, as of Mar 31, 2026

58 holders · 19.91M shares · 6 new positions · 28 increased · 13 reduced · 8 closed

HolderShares% outstandingChg q/qFiled
TCG Crossover Management, LLC3.03M6.42%0May 15, 2026
Siren, L.L.C.2.91M6.16%0May 14, 2026
Redmile Group, LLC2.16M4.58%0May 15, 2026
Nantahala Capital Management, LLC2.15M4.54%+604.3KMay 15, 2026
Citadel Advisors LLC1.23M2.61%+990.7KMay 15, 2026
Millennium Management LLC1.07M2.27%+414.6KMay 15, 2026
Great Point Partners LLC1.02M2.16%+212.5KMay 15, 2026
Nextech Invest, Ltd.952.4K2.02%0May 15, 2026

Beneficial owners13D/G · 5% or more, as filed

Holder% of classSharesFormFiled
Richard Ian Griffithsincl. Ora Capital Limited24.40%34.54M13DJun 25, 2025
Richard Griffiths7.97%14.39M13DAug 13, 2026

InsidersForm 4

InsiderRoleSharesFiled
Griffiths Richard Ian10 percent owner14.39MAug 13, 2026

1 ten-percent owner holds 14.39M shares by Form 4, outside the officers-and-directors figure above · 7 positions are filed in the unlisted share unit (123.4K shares), which no share count here divides

Latest trades

DateInsiderTypeSharesAvg priceOwned after
Aug 10, 2026
Richard Ian Griffiths10 percent owner
Sale · 11 lots5,484,320$16.004,797,166
Jul 6, 2026
Richard Ian Griffiths10 percent owner
Sale865,112$10.5310,281,486
Jul 2, 2026
Richard Ian Griffiths10 percent owner
Sale50,082$10.4711,146,598
Jul 1, 2026
Richard Ian Griffiths10 percent owner
Sale · 2 lots129,180$10.6211,196,680
Jun 30, 2026
Richard Ian Griffiths10 percent owner
Sale169,928$10.7611,325,860
Jun 29, 2026
Richard Ian Griffiths10 percent owner
Sale330,072$10.6911,495,788
Aug 3, 2025
Richard Ian Griffiths10 percent owner
Sale20,000$5.4511,805,861
Oct 27, 2025
Richard Ian Griffiths10 percent owner
Sale2,000$7.7511,819,861
Oct 27, 2025
Richard Ian Griffiths10 percent owner
Purchase2,000$7.7511,825,861
Aug 3, 2025
Richard Ian Griffiths10 percent owner
Purchase20,000$5.4511,825,861

CongressHouse and Senate disclosures

Not reported.