TScan Therapeutics
Develops TCR-engineered T-cell therapies for cancer through a T-cell receptor discovery platform.
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Profile
A clinical-stage biopharmaceutical company developing TCR-engineered T-cell therapies for cancer. It applies a T-cell receptor discovery platform to build a TCR-T pipeline rather than relying on an already marketed drug.
Develops T-cell receptor-engineered T-cell therapies for cancer as a clinical-stage biopharmaceutical company. Its TargetScan discovery technology is intended to reveal how T cells naturally recognize cancer and inform a pipeline of TCR-T candidates.
Founded in 2018 and headquartered in Waltham, Massachusetts, the company takes a platform-built approach rather than operating around an already marketed drug. Its progress depends on advancing TCR-T candidates and its discovery platform into therapies for cancer.
The company has also worked with Novartis to discover and develop TCR-engineered therapies for solid tumors, while retaining the ability to develop targets that Novartis does not license.
Company facts
Key statistics
Year to date −26.2% · Average volume (30d) 408.8K
Analysts
Ratings
Target range
Latest analyst notes
| Date | Firm | Action | Prior rating | Rating |
|---|---|---|---|---|
| Nov 4, 2025 | BTIG | Downgrade | Buy | Neutral |
Earnings
EPS
Revenue
History
| Report date | EPS est | EPS | Surprise | Revenue est | Revenue | Surprise | Next session |
|---|---|---|---|---|---|---|---|
| Aug 12, 2026Q2 FY26 | −$0.25 | −$0.23 | +9.2% | $1.9M | $1.1M | −43.9% | −0.49% |
| Aug 11, 2026Q2 FY26 | −$0.29 | −$0.23 | +20.7% | $1.9M | $1.1M | −43.9% | +1.28% |
| May 6, 2026Q1 FY26 | −$0.22 | −$0.22 | 0.0% | $2.5M | $982.0K | −60.7% | −3.20% |
| Mar 4, 2026Q4 FY25 | −$0.27 | −$0.18 | +33.3% | $2.4M | $2.6M | +5.4% | +4.63% |
Financial highlights
| 12 quarters | Q1 FY25 | Q2 FY25 | Q3 FY25 | Q4 FY25 | Q1 FY26 | Q2 FY26 | |
|---|---|---|---|---|---|---|---|
| Revenue | $2.2M | $3.1M | $2.5M | $2.6M | $982.0K | $1.1M | |
| Gross profit | $2.2M | $3.1M | $2.5M | $2.6M | $289.0K | $1.1M | |
| Operating income | −$36.3M | −$38.7M | −$37.1M | −$23.9M | −$29.1M | −$30.5M | |
| Net income | −$34.1M | −$37.0M | −$35.7M | −$23.0M | −$28.7M | −$30.4M | |
| Diluted EPS | −$0.26 | −$0.28 | −$0.28 | −$0.18 | −$0.22 | −$0.23 | |
| Gross margin | 100.0% | 100.0% | 100.0% | 100.0% | 29.4% | 100.0% | |
| Operating margin | -1,669.7% | -1,256.6% | -1,475.6% | -929.4% | -2,967.3% | -2,901.3% |
Fiscal years (4-quarter sums)FY21 $10.1M · FY22 $13.5M · FY23 $21.0M · FY24 $2.8M · FY25 $10.3M
Revenue by product · Q2 FY26
Balance sheet, Jun 30, 2026Cash & short-term investments $100.2M · Total debt $90.9M · Total assets $171.5M · Shareholders' equity $69.0M
Dividends
No dividends on record.
Ownership
Shares outstanding 61.07M · Float 55.39M · 90.7% free float
Insiders — no current Form 4 position.
A Form 4 total here can count shares the filer formally disclaims — an award voted by proxy, for instance — which the holder's own Schedule 13D/G excludes, so where the two disagree the schedule's smaller figure is used.
Top shareholders13F · 13D/G · Form 4
| Holder | Shares | % outstanding | Form | Filed |
|---|---|---|---|---|
| LYNX1 Capital Management LP | 8.02M | 13.13% | 13F | May 4, 2026 |
| BVF Inc/IL | 5.56M | 9.11% | 13F | May 15, 2026 |
| K2 HealthVentures Equity Trust LLC | 3.60M | 6.90% | 13G | Feb 14, 2025 |
| Biotechnology Value Fund L P | 3.01M | 5.40% | 13G | May 15, 2026 |
| Baker Bros. Advisors LP | 2.78M | 4.56% | 13F | May 15, 2026 |
Insider tradesForm 4
| Date | Insider | Role | Shares | Avg price |
|---|---|---|---|---|
| Dec 19, 2025 | Lynx1 Capital Management LP | 10 percent owner | +80,069 | $0.8989 |
| Dec 22, 2025 | Lynx1 Capital Management LP | 10 percent owner | +75,500 | $0.9000 |
| Dec 23, 2025 | Lynx1 Capital Management LP | 10 percent owner | +6,232 | $0.8989 |
Peers
- Immatics
Clinical TCR-T and TCR-bispecific programs for cancer
- Immunocore (ADR)
TCR-bispecific cancer medicines and HLA-restricted targets
- Iovance Biotherapeutics
Commercial and investigational tumor-infiltrating lymphocyte therapies
- Gilead Sciences
Kite cell therapies for aggressive blood cancers
CompareAfter-hours close
| Company | Price | Change | |||||
|---|---|---|---|---|---|---|---|
| TScan Therapeutics | $0.7535 | +0.15% | $46.0M | — | — | 6.5 | −65.8% |
| Immatics | $9.35 | −0.95% | $1.27B | — | — | 26.2 | +113.0% |
| Immunocore (ADR) | $36.62 | −0.03% | $1.86B | — | — | 4.6 | −13.7% |
| Iovance Biotherapeutics | $8.03 | +0.06% | $3.58B | — | — | 11.0 | +65.7% |
| Gilead Sciences | $139.30 | −4.36% | $180.87B | — | 16.0 | 5.9 | +10.2% |
| Median | — | 16.0 | 8.5 | +37.9% |






