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TCRX · NASDAQ · Biotechnology

TScan Therapeutics

Develops TCR-engineered T-cell therapies for cancer through a T-cell receptor discovery platform.

$0.7535
After-hours close+0.00 (+0.15%)
At close$0.7524(+0.29%)
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Profile

TScan Therapeutics, Inc.TCRXHealth Care

A clinical-stage biopharmaceutical company developing TCR-engineered T-cell therapies for cancer. It applies a T-cell receptor discovery platform to build a TCR-T pipeline rather than relying on an already marketed drug.

Develops T-cell receptor-engineered T-cell therapies for cancer as a clinical-stage biopharmaceutical company. Its TargetScan discovery technology is intended to reveal how T cells naturally recognize cancer and inform a pipeline of TCR-T candidates.

Founded in 2018 and headquartered in Waltham, Massachusetts, the company takes a platform-built approach rather than operating around an already marketed drug. Its progress depends on advancing TCR-T candidates and its discovery platform into therapies for cancer.

The company has also worked with Novartis to discover and develop TCR-engineered therapies for solid tumors, while retaining the ability to develop targets that Novartis does not license.

Company facts

CEOGavin MacBeath, Ph.D.
ListedJul 16, 2021
ExchangeNASDAQ
HeadquartersWaltham, MA
CountryUnited States
Employees142
CIK0001783328
ISINUS89854M1018

Key statistics

Market cap$46.0M
EPS (ttm)−$0.9100
P/E (ttm)−0.8280
ROE-108.7%
P/B1.42
P/S6.47
Dividend yield
Beta1.64vs XLV 0.71

Year to date −26.2% · Average volume (30d) 408.8K

Analysts

Price target, next 12 months$7.50+900.0%Median of 8 analysts · vs the Aug 28 close
ConsensusBuy7 of 8 analysts rate it buy or better

Ratings

Target range

Latest analyst notes

DateFirmActionPrior ratingRating
Nov 4, 2025BTIGDowngradeBuyNeutral

Earnings

EPS

Estimate−$0.30
ReportedDue Nov 11, 2026

Revenue

Estimate$1.5M
ReportedDue Nov 11, 2026

History

Report dateEPS estEPSSurpriseRevenue estRevenueSurpriseNext session
Aug 12, 2026Q2 FY26−$0.25−$0.23+9.2%$1.9M$1.1M−43.9%−0.49%
Aug 11, 2026Q2 FY26−$0.29−$0.23+20.7%$1.9M$1.1M−43.9%+1.28%
May 6, 2026Q1 FY26−$0.22−$0.220.0%$2.5M$982.0K−60.7%−3.20%
Mar 4, 2026Q4 FY25−$0.27−$0.18+33.3%$2.4M$2.6M+5.4%+4.63%
View details

Financial highlights

12 quartersQ1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Revenue$2.2M$3.1M$2.5M$2.6M$982.0K$1.1M
Gross profit$2.2M$3.1M$2.5M$2.6M$289.0K$1.1M
Operating income−$36.3M−$38.7M−$37.1M−$23.9M−$29.1M−$30.5M
Net income−$34.1M−$37.0M−$35.7M−$23.0M−$28.7M−$30.4M
Diluted EPS−$0.26−$0.28−$0.28−$0.18−$0.22−$0.23
Gross margin100.0%100.0%100.0%100.0%29.4%100.0%
Operating margin-1,669.7%-1,256.6%-1,475.6%-929.4%-2,967.3%-2,901.3%

Fiscal years (4-quarter sums)FY21 $10.1M · FY22 $13.5M · FY23 $21.0M · FY24 $2.8M · FY25 $10.3M

Revenue by product · Q2 FY26

Reportable Segment$1.1M · 100%

Balance sheet, Jun 30, 2026Cash & short-term investments $100.2M · Total debt $90.9M · Total assets $171.5M · Shareholders' equity $69.0M

Dividends

No dividends on record.

Ownership

Institutions 53.16%Insiders

Shares outstanding 61.07M · Float 55.39M · 90.7% free float

Insiders — no current Form 4 position.

A Form 4 total here can count shares the filer formally disclaims — an award voted by proxy, for instance — which the holder's own Schedule 13D/G excludes, so where the two disagree the schedule's smaller figure is used.

Top shareholders13F · 13D/G · Form 4

HolderShares% outstandingFormFiled
LYNX1 Capital Management LP8.02M13.13%13FMay 4, 2026
BVF Inc/IL5.56M9.11%13FMay 15, 2026
K2 HealthVentures Equity Trust LLC3.60M6.90%13GFeb 14, 2025
Biotechnology Value Fund L P3.01M5.40%13GMay 15, 2026
Baker Bros. Advisors LP2.78M4.56%13FMay 15, 2026

Insider tradesForm 4

DateInsiderRoleSharesAvg price
Dec 19, 2025Lynx1 Capital Management LP10 percent owner+80,069$0.8989
Dec 22, 2025Lynx1 Capital Management LP10 percent owner+75,500$0.9000
Dec 23, 2025Lynx1 Capital Management LP10 percent owner+6,232$0.8989
View details

Peers

CompareAfter-hours close

CompanyPriceChange
TScan Therapeutics$0.7535+0.15%$46.0M6.5−65.8%
Immatics$9.35−0.95%$1.27B26.2+113.0%
Immunocore (ADR)$36.62−0.03%$1.86B4.6−13.7%
Iovance Biotherapeutics$8.03+0.06%$3.58B11.0+65.7%
Gilead Sciences$139.30−4.36%$180.87B16.05.9+10.2%
Median16.08.5+37.9%