TGTX · NASDAQ · Biotechnology

TG Therapeutics

Commercializes BRIUMVI while developing B-cell therapies for immune-mediated diseases.

$53.93
After-hours close+0.02 (+0.04%)
At close$53.91(−3.25%)
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Profile

TG Therapeutics, Inc.TGTXHealth Care

Sells BRIUMVI, an infused anti-CD20 therapy for adults with relapsing multiple sclerosis, primarily through U.S. specialty distributors while earning supply, royalty, and support revenue from Neuraxpharm-led markets abroad. Revenue depends overwhelmingly on one product as development expands into new formulations, immune-mediated indications, and azer-cel cell therapy.

Commercializes BRIUMVI, an anti-CD20 antibody approved for adults with relapsing forms of multiple sclerosis. The commercial model combines direct U.S. marketing with sales through specialty distributors; Neuraxpharm commercializes the medicine in several markets outside the United States, generating supply, royalty, and regulatory-support revenue.

Lifecycle development covers a simplified intravenous initiation regimen and a subcutaneous formulation. Clinical programs also test BRIUMVI in myasthenia gravis and treatment-resistant schizophrenia, while azer-cel, an allogeneic CAR T therapy, is being studied in progressive multiple sclerosis and other B-cell disorders.

Revenue remains overwhelmingly tied to U.S. BRIUMVI sales. Manufacturing is outsourced, ublituximab carries licensing royalties, overseas commercialization depends on Neuraxpharm, and pipeline expansion depends on clinical evidence and regulatory approval.

Company facts

CEOMichael S. Weiss
ListedMay 3, 2010
ExchangeNASDAQ
HeadquartersMorrisville, NC
CountryUnited States
Employees399
CIK0001001316
ISINUS88322Q1085

Key statistics

Market cap$8.26B
EPS (ttm)$2.74
P/E (ttm)19.68
ROE72.3%
P/B12.66
P/S10.33
Dividend yield
Beta0.62vs XLV 0.55

Year to date +84.1% · Average volume (30d) 2.2M

Analysts

Price target, next 12 months$80.50+49.3%Median of 13 analysts · vs the Aug 28 close
ConsensusBuy11 of 13 analysts rate it buy or better

Ratings

Target range

Latest analyst notes

DateFirmActionRatingPrior targetTarget
Aug 4, 2026H.C. WainwrightReiterateBuy$70$78
Jun 22, 2026JefferiesReiterateBuy$83
May 6, 2026H.C. WainwrightTarget$60$70
Jan 14, 2026Goldman SachsTarget$20$39
Oct 6, 2025H.C. WainwrightTarget$55$60

Earnings

EPS

Estimate$0.36
ReportedDue Nov 2, 2026

Revenue

Estimate$247.1M
ReportedDue Nov 2, 2026

History

Report dateEPS estEPSSurpriseRevenue estRevenueSurpriseNext session
Aug 3, 2026Q2 FY26$0.31$0.05−83.6%$229.8M$240.3M+4.6%−11.26%
May 6, 2026Q1 FY26$0.23$0.17−26.1%$200.3M$204.9M+2.3%+2.53%
Feb 26, 2026Q4 FY25$0.35$0.14−60.0%$191.8M$192.6M+0.4%−2.62%
Nov 3, 2025Q3 FY25$0.24$2.43+912.5%$193.8M$161.7M−16.6%+0.36%
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Financial highlights

12 quartersQ1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Revenue$120.9M$141.1M$161.7M$192.6M$204.9M$240.3M
Gross profit$105.3M$122.2M$133.6M$154.4M$171.4M$199.1M
Operating income$8.6M$34.8M$29.4M$50.5M$34.8M$21.7M
Net income$5.1M$28.2M$390.9M$23.0M$19.8M$7.8M
Diluted EPS$0.03$0.17$2.43$0.14$0.12$0.05
Gross margin87.1%86.6%82.6%80.2%83.6%82.9%
Operating margin7.1%24.7%18.2%26.2%17.0%9.0%

Fiscal years (4-quarter sums)FY21 $6.7M · FY22 $2.8M · FY23 $233.7M · FY24 $329.0M · FY25 $616.3M

Revenue by product · Q2 FY26

Product$235.8M · 98%
License Revenue$4.5M · 2%

Revenue by geography · Q2 FY26

United States$227.7M · 100%

Balance sheet, Jun 30, 2026Cash & short-term investments $552.2M · Total debt $754.4M · Total assets $1.64B · Shareholders' equity $604.1M

Dividends

No dividends on record.

Ownership

Institutions 79.56%121.79M sharesInsiders 7.54%11.54M sharesOther 12.90%19.75M shares

Shares outstanding 153.08M · Float 135.10M · 88.3% free float

Top shareholders13F · 13D/G · Form 4

HolderShares% outstandingFormFiled
BlackRock, Inc.22.05M14.40%13FAug 7, 2026
Michael S. Weiss · director, officer: CEO9.78M6.39%Form 4Jan 9, 2026
Vanguard Portfolio Management LLC7.96M5.20%13FAug 13, 2026
State Street Corp7.79M5.09%13FAug 7, 2026
Vanguard Capital Management LLC6.15M4.02%13FAug 13, 2026

Insider tradesForm 4

DateInsiderRoleSharesAvg price
Nov 24, 2025Yann Echelarddirector−5,000$32.57
Sep 11, 2025Sagar Lonialdirector−20,852$32.24
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Peers

  • Novartis (ADR)

    Direct self-administered anti-CD20 rival in relapsing MS

  • Biogen

    Established MS franchise with high-efficacy infusion alternatives

  • Bristol-Myers Squibb

    Oral S1P RMS alternative competing with infusion anti-CD20 therapy

  • Sanofi (ADR)

    Established RMS DMTs plus BTK pressure in progressive MS

  • Johnson & Johnson

    Oral ponesimod option in relapsing MS treatment selection

CompareAfter-hours close

CompanyPriceChange
TG Therapeutics$53.93+0.04%$8.26B19.728.410.3+70.3%
Novartis (ADR)$153.810.00%$292.35B23.216.45.3+0.9%
Biogen$218.19−0.14%$32.28B38.716.53.2+3.4%
Bristol-Myers Squibb$66.60+0.05%$136.00B14.710.52.8+5.7%
Sanofi (ADR)$44.83+0.02%$107.62B78.91.9+11.2%
Johnson & Johnson$268.40+0.13%$645.95B31.122.46.6+6.6%
Median31.116.53.2+5.7%