UTHR · NASDAQ · Biotechnology

United Therapeutics

Builds pulmonary-hypertension medicines and investigational organ-manufacturing platforms.

$515.46
After-hours close+0.15 (+0.03%)
At close$515.31(−2.39%)
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Profile

United Therapeutics CorporationUTHRHealth Care

Develops treatments for pulmonary hypertension and high-risk neuroblastoma, with inhaled Tyvaso anchoring a portfolio that spans multiple treprostinil delivery formats. Commercial medicines are concentrated in the United States and fund investigational programs in gene-edited pig organs, patient-derived grafts, and recellularized scaffolds.

Develops and commercializes medicines for pulmonary hypertension and high-risk neuroblastoma, led by the inhaled Tyvaso franchise. Remodulin and Orenitram extend treprostinil across infused and oral formats, while Adcirca and Unituxin broaden the approved portfolio.

Commercial execution centers on multiple delivery options for chronic pulmonary vascular disease. Tyvaso DPI and Orenitram are sold only in the United States, while nebulized Tyvaso, Remodulin, and Unituxin also generate international revenue.

Uses cash from approved medicines to develop manufactured-organ alternatives through gene-edited pig organs, patient-derived grafts, and recellularized scaffolds. Those programs remain investigational. The commercial business is concentrated in treprostinil therapies and specialty-pharmacy distribution, with product differentiation, patent outcomes, physician sequencing, regulatory compliance, and uncertain organ-development pathways shaping the model.

Company facts

CEOMartine Rothblatt
ListedJun 17, 1999
ExchangeNASDAQ
HeadquartersSilver Spring, MD
CountryUnited States
Employees1,400
CIK0001082554
ISINUS91307C1027

Key statistics

Market cap$21.88B
EPS (ttm)$27.91
P/E (ttm)18.47
ROE20.2%
P/B3.43
P/S6.94
Dividend yield
Beta0.10vs XLV 0.59

Year to date +3.7% · Average volume (30d) 470.5K

Analysts

Price target, next 12 months$662.50+28.5%Median of 30 analysts · vs the Aug 28 close
ConsensusBuy17 of 30 analysts rate it buy or better

Ratings

Target range

Latest analyst notes

DateFirmActionPrior ratingRatingPrior targetTarget
Aug 6, 2026Morgan StanleyTarget$516$515
May 7, 2026Morgan StanleyTarget$519$516
May 7, 2026Wells FargoUpgradeEqual WeightOverweight$738$735
Apr 10, 2026Morgan StanleyReiterateEqual Weight$447$519
Apr 10, 2026Raymond JamesTarget$700

Earnings

EPS

Estimate$6.54
ReportedDue Nov 4, 2026

Revenue

Estimate$789.5M
ReportedDue Nov 4, 2026

History

Report dateEPS estEPSSurpriseRevenue estRevenueSurpriseNext session
Aug 5, 2026Q2 FY26$6.86$7.27+6.0%$804.6M$783.3M−2.7%+0.06%
May 6, 2026Q1 FY26$7.00$5.82−16.9%$797.4M$781.5M−2.0%−4.62%
Feb 25, 2026Q4 FY25$7.13$7.70+8.0%$813.1M$790.2M−2.8%−5.89%
Oct 29, 2025Q3 FY25$6.89$7.16+3.9%$814.8M$799.5M−1.9%−0.39%
View details

Financial highlights

12 quartersQ1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Revenue$794.4M$798.6M$799.5M$790.2M$781.5M$783.3M
Gross profit$701.9M$711.0M$698.6M$686.8M$648.1M$683.8M
Operating income$382.8M$364.5M$389.3M$357.5M$325.8M$330.8M
Net income$322.2M$309.5M$338.7M$364.3M$274.9M$333.0M
Diluted EPS$6.63$6.41$7.16$7.66$5.82$7.27
Gross margin88.4%89.0%87.4%86.9%82.9%87.3%
Operating margin48.2%45.6%48.7%45.2%41.7%42.2%

Fiscal years (4-quarter sums)FY21 $1.69B · FY22 $1.94B · FY23 $2.33B · FY24 $2.88B · FY25 $3.18B

Revenue by product · Q2 FY26

Tyvaso$452.6M · 58%
Remodulin$126.3M · 16%
Orenitram$125.7M · 16%
Unituxin$65.2M · 8%
Product And Service, Other$6.8M · 1%
Adcirca$6.7M · 1%

Revenue by geography · Q2 FY26

United States$733.6M · 94%
Non-US$49.7M · 6%

Balance sheet, Jun 30, 2026Cash & short-term investments $2.66B · Total debt $0 · Total assets $7.22B · Shareholders' equity $6.40B

Dividends

No dividends on record.

Ownership

Institutions 177.21%Insiders 1.21%

A 13F quarter can total more than the shares outstanding — sub-advisers file the same block twice, and a filer's own share count can be a quarter stale. No split is drawn from it.

Shares outstanding 42.45M · Float 39.32M · 92.6% free float

Top shareholders13F · 13D/G · Form 4

HolderShares% outstandingFormFiled
BlackRock, Inc.5.29M12.47%13FAug 7, 2026
Avoro Capital Advisors LLC2.78M6.54%13FAug 14, 2026
Vanguard Portfolio Management LLC1.92M4.52%13FAug 13, 2026
Vanguard Capital Management LLC1.92M4.52%13FAug 13, 2026
State Street Corp1.90M4.47%13FAug 7, 2026

Insider tradesForm 4

DateInsiderRoleSharesAvg price
Aug 27, 2026Martine A. Rothblattdirector, officer: Chairperson & CEO−9,500$522.57
Aug 26, 2026Martine A. Rothblattdirector, officer: Chairperson & CEO−9,500$517.28
Aug 25, 2026Martine A. Rothblattdirector, officer: Chairperson & CEO−9,500$517.71
Aug 24, 2026Martine A. Rothblattdirector, officer: Chairperson & CEO−9,500$511.97
Aug 21, 2026Martine A. Rothblattdirector, officer: Chairperson & CEO−9,500$518.39
View details

Peers

  • Liquidia

    Direct inhaled-treprostinil rival across PAH and PH-ILD

  • Johnson & Johnson

    Broad PAH rival across oral, infused, and combination therapies

  • Merck

    PAH treatment-sequencing rival built around WINREVAIR

CompareAfter-hours close

CompanyPriceChange
United Therapeutics$515.46+0.03%$21.88B18.519.86.9−1.9%
Liquidia$68.25+0.87%$6.02B49.415.413.3+1,842.7%
Johnson & Johnson$268.40+0.13%$645.95B31.122.46.6+6.6%
Merck$148.19−0.08%$366.18B118.717.25.5+5.1%
Median49.417.26.6+6.6%