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CALC · NASDAQ · Biotechnology

CalciMedica (CALC)

Develops CRAC-channel inhibitors for inflammatory and cardiopulmonary disease.

$2.24
Pre-market+0.17 (+7.95%)
At close$2.08(+3.75%)

Breakdown13F · 13D/G · Form 4

Institutions28 holders · as of Mar 31, 20263.22%219.6K shares
Insiders10 holders · as of Jul 7, 202619.33%1.32M shares
Strategic holders2 holders · as of Jul 10, 202617.42%1.19M shares
Otherremainder60.03%4.10M shares

6.83M company shares as of Sep 3, 2026 · institutions as of Mar 31, 2026 · holders as of their latest filing

Two share counts disagree (6.83M in the company's Sep 3, 2026 report, 3.15M elsewhere); stakes use the report.

Top shareholders13F · 13D/G · Form 4

HolderStakeSharesEvidence
Alafi Capital Co LLCStrategic10 percent owner
14.97%1.02MForm 4filed Jul 10, 2026
Evgeny ZaytsevInsiderdirector
6.19%422,703Form 4filed Jul 7, 2026
Robert N. WilsonInsiderdirector
4.70%320,930Form 4filed Jun 29, 2026
Fred A. MiddletonInsiderdirector, 10 percent owner
3.22%219,957Form 4filed Jun 29, 2026
Sanderling Venture Partners VI Co Investment Fund LPStrategic10 percent owner
2.45%167,356Form 4filed Nov 5, 2024
Laurence W. LyttonInsider
2.21%151,23613Gfiled Jul 8, 2024
Eric W. RobertsInsiderdirector, 10 percent owner, officer: CHIEF BUSINESS OFFICER
1.32%90,117Form 4filed Jun 29, 2026
A. Rachel LehenyInsiderdirector, 10 percent owner, officer: CHIEF EXECUTIVE OFFICER
0.94%64,231Form 4filed Jun 29, 2026
Sudarshan HebbarInsiderofficer: Chief Medical Officer
0.54%37,205Form 4filed Jun 29, 2026
Jane Street Group, LLCInstitution
0.52%178,51513Fas of Mar 31, 2026
Vanguard Capital Management LLCInstitution
0.50%169,11013Fas of Mar 31, 2026
Renaissance Technologies LLCInstitution
0.38%128,07513Fas of Mar 31, 2026
180 Wealth Advisors, LLCInstitution
0.37%126,50013Fas of Mar 31, 2026
Geode Capital Management, LLCInstitution
0.36%123,38213Fas of Mar 31, 2026
Cambridge Investment Research Advisors, Inc.Institution
0.18%60,00013Fas of Mar 31, 2026
Stonehage Fleming Financial Services Holdings LtdInstitution
0.16%53,70313Fas of Mar 31, 2026
Vanguard Fiduciary Trust CoInstitution
0.13%45,82913Fas of Mar 31, 2026
Stephen BardinInsiderofficer: Chief Financial Officer
0.13%8,800Form 4filed Jun 26, 2025
HRT Financial LPInstitution
0.12%39,69913Fas of Mar 31, 2026
Susquehanna International Group, LLPInstitution
0.09%30,71613Fas of Mar 31, 2026
Gsa Capital Partners LLPInstitution
0.07%23,77713Fas of Mar 31, 2026
Virtu Financial LLCInstitution
0.05%17,89513Fas of Mar 31, 2026
State Street CorpInstitution
0.05%17,07313Fas of Mar 31, 2026
Tritonpoint Partners, LLCInstitution
0.04%15,11913Fas of Mar 31, 2026
First Manhattan Co. LLC.Institution
0.04%13,22613Fas of Mar 31, 2026

13F — a manager's quarterly holdings · 13D/13G — an ownership statement filed at 5% or more · Form 4 — an insider's transaction report

Institutions13F, as of Mar 31, 2026

28 holders · 1.10M shares · 12 new positions · 16 increased · 5 reduced · 15 closed

HolderShares% outstandingChg q/qFiled
Jane Street Group, LLC178.5K2.61%+159.3KMay 12, 2026
Vanguard Capital Management LLC169.1K2.48%+169.1KnewMay 15, 2026
Renaissance Technologies LLC128.1K1.88%+39.8KMay 14, 2026
180 Wealth Advisors, LLC126.5K1.85%+94.7KMay 1, 2026
Geode Capital Management, LLC123.4K1.81%+23.6KMay 15, 2026
Cambridge Investment Research Advisors, Inc.60.0K0.88%+60.0KnewApr 30, 2026
Stonehage Fleming Financial Services Holdings Ltd53.7K0.79%0May 13, 2026
Vanguard Fiduciary Trust Co45.8K0.67%+45.8KnewMay 8, 2026

Ownership statements13D/G · 5% or more, as filed

Holder% of classSharesFormFiled
Alafi Capital Company LLCincl. Christopher D. Alafi19.90%13DAug 24, 2026
Fred A. Middletonincl. Sanderling Ventures VII (Canada), L.P., Sanderling Ventures Management VI +8 more18.30%13DNov 26, 2024
Bering Partners II GP, L.L.C.9.99%13DAug 21, 2026
Armistice Capital, LLC9.99%13GAug 14, 2026
Woodline Partners LP8.10%13GAug 14, 2026
Eric W. Robertsincl. A. Rachel Leheny, Valence Investments SPV IV, LLC +2 more6.40%13DJun 30, 2026
Stonepine Capital Management, LLC6.00%13GAug 25, 2026
Bering Partners II, L.P. ("Bering II")5.80%13GOct 29, 2025
CVI Investments, Inc.5.10%13GJul 20, 2026

Insider tradesForm 4

Latest trades

DateInsiderTypeSharesAvg priceOwned after
Jun 25, 2026
Fred A. Middletondirector, 10 percent owner:
Purchase248,972$0.80331,063,272
Sep 18, 2025
Eric W. Robertsdirector, 10 percent owner, officer: CHIEF BUSINESS OFFICER
Purchase2,500$3.0784,150
Sep 15, 2025
Eric W. Robertsdirector, 10 percent owner, officer: CHIEF BUSINESS OFFICER
Purchase3,400$2.6881,650
Sep 12, 2025
Eric W. Robertsdirector, 10 percent owner, officer: CHIEF BUSINESS OFFICER
Purchase5,000$3.1278,250
Sep 9, 2025
Eric W. Robertsdirector, 10 percent owner, officer: CHIEF BUSINESS OFFICER
Purchase2,343$3.1573,250

CongressHouse and Senate disclosures

Not reported.