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CALC · NASDAQ · Biotechnology

CalciMedica (CALC)

Develops CRAC-channel inhibitors for inflammatory and cardiopulmonary disease.

$2.10
Pre-market+0.02 (+1.20%)
At close$2.08(+3.75%)
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CalciMedica, Inc.CALCHealth Care

Develops CRAC-channel inhibitors for inflammatory and cardiopulmonary disease, led by the clinical candidate Auxora. Operates as a single, pre-revenue development business, funding outsourced research and manufacturing through equity capital.

Develops CRAC-channel inhibitors for inflammatory and cardiopulmonary disease, with Auxora as the lead clinical candidate. The California-based operation also has CM5480 in IND-enabling development, while CARPO and KOURAGE are trials of Auxora rather than separate product lines.

Operates as a single research-and-development segment with no approved products or product revenue. Development and manufacturing rely heavily on outside vendors, and operations depend on equity capital rather than customer sales.

Progress depends on clinical evidence, regulatory authorization, trial enrollment, intellectual-property protection and the capacity of contract research, clinical-site and manufacturing partners. The public issuer emerged from a reverse merger and must meet Nasdaq listing and SEC reporting standards.

Company facts

CEORachel K. Leheny, Ph.D.
ListedMar 21, 2023
ExchangeNASDAQ
HeadquartersLa Jolla, CA
CountryUnited States
Employees16
CIK0001534133
ISINUS38942Q2021

Market cap$6.6M
EPS (ttm)−$1.99
P/E (ttm)−1.06
ROE3,398.4%
P/B1.30
P/S0.00
Dividend yieldDiv yield
Beta0.64vs XLV 0.61

Unavailable right now.

Next report
Nov 11, 2026
estimated · in 69 days
EPS estimate
−$1.28
Revenue estimate
Fiscal quarter
Q3 FY26

EPSReportedEstimate

Mar '25May '25Aug '25Nov '25Mar '26May '26Aug '26Nov '26
Reported−$0.34−$0.36−$0.40−$0.39−$0.32−$0.22−$0.45Pending
Estimate−$0.48−$0.43−$0.40−$0.41−$0.55−$0.28−$0.29−$1.28
Surprise+29.2%+16.3%0.0%+4.9%+41.8%+21.4%−57.9%

RevenueReportedEstimate

Mar '25May '25Aug '25Nov '25Mar '26May '26Aug '26Nov '26
ReportedPending
Estimate$33.3M
Surprise
Estimate−$1.28
ReportedDue Nov 11, 2026
Estimate
ReportedDue Nov 11, 2026
View details

Debt to equity0.00%
Current ratio557.70%

ProfitabilityRevenueNet incomeNet margin

Q3 FY24Q4 FY24Q1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Revenue$0$0$0$0$0$0$0$0
Net income−$5.6M−$4.3M−$5.0M−$6.0M−$7.8M−$10.8M$5.0M−$7.7M
Net margin

GrowthOperating income

Q3 FY24Q4 FY24Q1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Operating income−$5.7M−$6.2M−$6.5M−$6.6M−$5.6M−$4.4M−$5.6M−$4.0M
YoY growth

Balance sheet, Jun 30, 2026Cash & short-term investments $18.6M · Total debt $0 · Total assets $19.5M · Shareholders' equity $5.5M

Revenue
$0
Operating income
−$4.0M
Net income
−$7.7M
View details

No dividends on record.

Institutions28 holders · as of Mar 31, 20263.22%219.6K shares
Insiders10 holders · as of Jul 7, 202619.33%1.32M shares
Strategic holders2 holders · as of Jul 10, 202617.42%1.19M shares
Otherremainder60.03%4.10M shares

6.83M company shares as of Sep 3, 2026 · institutions as of Mar 31, 2026 · holders as of their latest filing

Two share counts disagree (6.83M in the company's Sep 3, 2026 report, 3.15M elsewhere); stakes use the report.

Top shareholders13F · 13D/G · Form 4

HolderStakeSharesEvidence
Alafi Capital Co LLCStrategic10 percent owner
14.97%1.02MForm 4filed Jul 10, 2026
Evgeny ZaytsevInsiderdirector
6.19%422,703Form 4filed Jul 7, 2026
Robert N. WilsonInsiderdirector
4.70%320,930Form 4filed Jun 29, 2026
Fred A. MiddletonInsiderdirector, 10 percent owner
3.22%219,957Form 4filed Jun 29, 2026
Sanderling Venture Partners VI Co Investment Fund LPStrategic10 percent owner
2.45%167,356Form 4filed Nov 5, 2024
See all 25

Form 4 — an insider's transaction report

Insider tradesForm 4

DateInsiderRoleSharesAvg price
Jun 25, 2026Fred A. Middletondirector, 10 percent owner: +248,972$0.8033
Sep 18, 2025Eric W. Robertsdirector, 10 percent owner, officer: CHIEF BUSINESS OFFICER+2,500$3.07
Sep 15, 2025Eric W. Robertsdirector, 10 percent owner, officer: CHIEF BUSINESS OFFICER+3,400$2.68
Sep 12, 2025Eric W. Robertsdirector, 10 percent owner, officer: CHIEF BUSINESS OFFICER+5,000$3.12
Sep 9, 2025Eric W. Robertsdirector, 10 percent owner, officer: CHIEF BUSINESS OFFICER+2,343$3.15
View details

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ComparePre-market

CompanyPriceChange
CalciMedica$2.10+1.20%$6.6M
United Therapeutics$492.02+0.01%$20.88B17.618.96.6−1.9%
Johnson & Johnson$275.01−0.08%$663.23B31.923.16.8+6.6%
Merck$151.14−0.33%$374.52B121.317.65.6+5.1%
Median31.918.96.6+5.1%