CGEN · NASDAQ · Biotechnology

Compugen (CGEN)

Builds cancer immunotherapies from computationally predicted drug targets.

$2.65
Pre-market+0.03 (+1.00%)
At close$2.63(+1.35%)
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Compugen Ltd.CGENHealth Care

Develops cancer immunotherapies using the Unigen™ computational platform, which predicts drug targets and biological pathways. Selected outputs are advanced internally or through pharmaceutical partners, combining clinical-stage programs with licensing and royalty interests.

Uses the Unigen™ computational platform to predict drug targets and biological pathways for cancer immunotherapy. The platform combines biological data, internal scientific knowledge, AI/ML predictive algorithms, and a cloud-based knowledgebase, with feedback from preclinical and clinical work enriching that knowledgebase. It is technology-agnostic and AI/ML-enabled, directly linking discoveries to therapeutic drug development.

Advances selected platform outputs internally as clinical-stage immuno-oncology programs and through pharmaceutical partnerships. The business combines therapeutic development with licensing and royalty interests, including Gilead's licensed anti-IL-18 binding-protein antibody program and a royalty interest connected to AstraZeneca's rilvegostomig.

Company facts

CEOEran Ophir, Ph.D.
ListedAug 11, 2000
ExchangeNASDAQ
HeadquartersHolon, Israel
CountryIsrael
Employees75
CIK0001119774
ISINIL0010852080

Market cap$248.7M
EPS (ttm)$0.3754
P/E (ttm)7.01
ROE42.6%
P/B2.81
P/S3.36
Dividend yieldDiv yield
Beta1.75vs XLV 0.01

Price target$5.00+90.1%Avg of 14 analysts
ConsensusBuy13 of 14 analysts
Ratings

Target rangeAs of Sep 2, 2026

Latest analyst notes

DateFirmActionRatingTarget
May 21, 2026Leerink PartnersReiterateOutperform$5
Jan 7, 2026H.C. WainwrightTarget$4

Next report
Nov 9, 2026
in 67 days
EPS estimate
−$0.07
Revenue estimate
$1.3M
Fiscal quarter
Q3 FY26

EPSReportedEstimate

Mar '25May '25Aug '25Nov '25Mar '26May '26Aug '26Nov '26
Reported−$0.07−$0.08−$0.08−$0.07$0.60−$0.08−$0.07Pending
Estimate$0.07−$0.06−$0.07−$0.09−$0.07−$0.07−$0.08−$0.07
Surprise−200.0%−33.3%−14.3%+22.2%+957.1%−14.3%+12.5%

RevenueReportedEstimate

Mar '25May '25Aug '25Nov '25Mar '26May '26Aug '26Nov '26
Reported$1.5M$2.3M$1.3M$1.9M$67.3M$2.2M$2.6MPending
Estimate$5.0M$3.7M$1.5M$14.3M$2.2M$1.6M$1.3M$1.3M
Surprise−70.6%−38.3%−14.5%−86.8%+3,018.2%+38.5%+102.6%
Estimate−$0.07
ReportedDue Nov 9, 2026
Estimate$1.3M
ReportedDue Nov 9, 2026
View details

Debt to equity3.40%
Current ratio571.80%

ProfitabilityRevenueNet incomeNet margin

Q3 FY24Q4 FY24Q1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Revenue$17.1M$1.5M$2.3M$1.3M$1.9M$67.3M$2.2M$2.6M
Net income$1.3M−$6.1M−$7.2M−$7.3M−$7.0M$56.8M−$7.7M−$7.0M
Net margin7.4%0.0%0.0%0.0%0.0%84.4%0.0%0.0%

GrowthOperating income

Q3 FY24Q4 FY24Q1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Operating income$4.5M−$7.5M−$8.4M−$8.4M−$7.9M$56.0M−$9.0M−$8.8M
YoY growth−141.6%−275.6%

Balance sheet, Jun 30, 2026Cash & short-term investments $125.3M · Total debt $3.0M · Total assets $138.4M · Shareholders' equity $88.7M

Revenue
$2.6M
Operating income
−$8.8M
Net income
−$7.0M
View details

No dividends on record.

Institutions81 holders · as of Mar 31, 202615.02%14.21M ADS
Insiders12 holders · as of Jul 30, 20260.43%406.4K ADS
Strategic holders1 holder · as of Nov 19, 20215.03%4.76M ADS
Otherremainder79.52%75.18M ADS

94.55M ADS as of Sep 3, 2026 · institutions as of Mar 31, 2026 · holders as of their latest filing

Top shareholders13F · 13D/G · Form 4

HolderStakeSharesEvidence
Nikko Asset Management Americas, Inc.Institution
7.40%7.00M13G/Afiled Feb 14, 2022
Bristol Myers Squibb CoStrategic
5.03%4.76M13Gfiled Nov 19, 2021
Silverarc Capital Management, LLCInstitution
3.51%3.32M ADS13Fas of Mar 31, 2026
Renaissance Technologies LLCInstitution
1.73%1.63M ADS13Fas of Mar 31, 2026
Morgan StanleyInstitution
1.11%1.05M ADS13Fas of Mar 31, 2026
See all 25

13F — a manager's quarterly holdings · 13D/13G — an ownership statement filed at 5% or more

Insider tradesForm 4

DateInsiderRoleSharesAvg price
Jul 9, 2026Zurit Levineofficer: SVP, Business Development−1,875$2.50
Apr 24, 2026Eran Ophirdirector, officer: President and CEO−5,000$3.20
Apr 24, 2026Zurit Levineofficer: SVP, Business Development−2,000$3.20
Apr 14, 2026Zurit Levineofficer: SVP, Business Development−2,000$2.80
Apr 14, 2026Eran Ophirdirector, officer: President and CEO−5,000$2.90
View details

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