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CVKD · NASDAQ · Biotechnology

Cadrenal Therapeutics

Developer of anticoagulation candidates for high-risk hospital and cardiovascular care.

$1.40
Pre-market−0.35 (−19.77%)
At close$1.75(+13.31%)
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Profile

Cadrenal Therapeutics, Inc. Common StockCVKDHealth Care

Develops anticoagulation and thrombo-inflammation candidates for high-risk hospital and cardiovascular patients, seeking future revenue from approvals, product sales, and partnership or royalty arrangements. Its lean model depends on third parties and licensed or regionally split rights.

Develops CAD-1005, tecarfarin, and frunexian for high-risk anticoagulation needs across heparin-induced thrombocytopenia, complex chronic care, and acute hospital settings. No candidate currently has regulatory approval or generates product revenue; prospective economics depend on successful development and approval, product sales, and licensing, co-development, monetization, or royalty arrangements.

Operates through a lean, outsourced model, relying on third parties for clinical, regulatory, and manufacturing work while pursuing pharmaceutical partners for the cardiovascular portfolio. CAD-1005's worldwide rights depend on an Old Dominion University license; frunexian rights exclude China, where Haisco controls development and commercialization.

Company facts

CEOQuang X. Pham
ListedJan 20, 2023
ExchangeNASDAQ
HeadquartersPonte Vedra, FL
CountryUnited States
Employees5
CIK0001937993
ISINUS1276362076

Key statistics

Market cap$6.2M
EPS (ttm)−$4.90
P/E (ttm)−0.3571
ROE-406.4%
P/B1.25
P/S0.00
Dividend yieldDiv yield
Beta2.11vs XLV 0.59

Analysts

No analyst consensus on record.

Earnings

Next report
Nov 9, 2026
estimated · in 69 days
EPS estimate
−$1.00
Revenue estimate
Fiscal quarter
Q3 FY26

EPSReportedEstimate

Mar '25May '25Aug '25Nov '25Mar '26May '26Aug '26Nov '26
Reported−$2.74−$2.09−$1.87−$1.31−$1.41−$1.04−$1.14Pending
Estimate−$1.71−$1.64−$1.60−$1.55−$1.17−$1.51−$1.42−$1.00
Surprise−60.2%−27.4%−16.9%+15.5%−20.5%+31.1%+19.7%

RevenueReportedEstimate

Mar '25May '25Aug '25Nov '25Mar '26May '26Aug '26Nov '26
Reported$2.1KPending
Estimate
Surprise
Estimate−$1.00
ReportedDue Nov 9, 2026
Estimate
ReportedDue Nov 9, 2026
View details

Financials

Debt to equity0.00%
Current ratio373.00%

ProfitabilityRevenueNet incomeNet margin

Q3 FY24Q4 FY24Q1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Revenue$0$0$0$0$0$0$0$0
Net income−$2.4M−$4.2M−$3.8M−$3.7M−$2.7M−$3.0M−$2.5M−$3.3M
Net margin

GrowthOperating income

Q3 FY24Q4 FY24Q1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Operating income−$2.5M−$4.3M−$3.9M−$3.7M−$2.7M−$3.1M−$2.5M−$3.3M
YoY growth

Balance sheet, Jun 30, 2026Cash & short-term investments $2.4M · Total debt $0 · Total assets $5.6M · Shareholders' equity $4.1M

Revenue
$0
Operating income
−$3.3M
Net income
−$3.3M
View details

Dividends

No dividends on record.

Ownership

Institutions17 holders · as of Mar 31, 20262.55%90.9K shares
Insiders2 holders · as of Jul 1, 20262.81%100.3K shares
Otherremainder94.64%3.38M shares

3.57M company shares as of Sep 1, 2026 · institutions as of Mar 31, 2026 · holders as of their latest filing

Top shareholders13F · 13D/G · Form 4

HolderStakeSharesEvidence
Quang X. PhamInsiderdirector, 10 percent owner, officer: Chairman and CEO
2.76%98,589Form 4filed Jul 1, 2026
Vanguard Capital Management LLCInstitution
1.27%45,20113Fas of Mar 31, 2026
Geode Capital Management, LLCInstitution
0.61%21,62613Fas of Mar 31, 2026
Vanguard Fiduciary Trust CoInstitution
0.23%8,31113Fas of Mar 31, 2026
JPMorgan Chase & CoInstitution
0.21%7,50013Fas of Mar 31, 2026
See all 24

13F — a manager's quarterly holdings · Form 4 — an insider's transaction report

Insider tradesForm 4

DateInsiderRoleSharesAvg price
Jun 29, 2026Quang X. Phamdirector, 10 percent owner, officer: Chairman and CEO−7,400$3.03
Jun 26, 2026Quang X. Phamdirector, 10 percent owner, officer: Chairman, CEO and Interim CFO−9,029$3.05
Jun 25, 2026Quang X. Phamdirector, 10 percent owner, officer: Chairman, CEO and Interim CFO−2,127$3.00
Jun 23, 2026Quang X. Phamdirector, 10 percent owner, officer: Chairman, CEO and Interim CFO−2,277$3.20
Jun 22, 2026Quang X. Phamdirector, 10 percent owner, officer: Chairman, CEO and Interim CFO−9,167$3.55
View details

Peers

  • Pfizer

    Argatroban anchors HIT care; Eliquis overlaps in chronic anticoagulation.

  • Bristol-Myers Squibb

    Eliquis is the leading branded DOAC against tecarfarin's target use.

  • Johnson & Johnson

    Xarelto supplies a broad DOAC alternative in chronic cardiovascular care.

ComparePre-market

CompanyPriceChange
Cadrenal Therapeutics$1.40−19.77%$6.2M
Pfizer$28.48+0.07%$162.21B37.610.22.5+2.6%
Bristol-Myers Squibb$66.93+0.19%$136.47B14.710.52.8+5.7%
Johnson & Johnson$266.13+0.10%$640.67B30.822.36.5+6.6%
Median30.810.52.8+5.7%