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Kairos Pharma (KAPA)

Develops resistance-focused cancer therapies led by ENV-105.

$1.69
Pre-market+0.08 (+4.97%)
At close$1.61(−2.42%)
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Kairos Pharma, Ltd.KAPAHealth Care

Develops oncology therapies designed to counter treatment resistance and immune suppression, led by ENV-105 in prostate cancer and EGFR-mutated lung cancer. It is a virtual, pre-revenue clinical-stage company whose development work depends on academic sites, third-party providers and licensed Cedars-Sinai intellectual property.

Develops cancer therapies intended to address drug resistance and immune suppression, with ENV-105, a CD105-targeting antibody, as the clinical lead. The program is being tested alongside androgen-receptor signaling inhibitors in prostate cancer and osimertinib in EGFR-mutated lung cancer. Earlier programs include activated T cells for glioblastoma and small molecules and biologics spanning immune modulation, tumor biology and cachexia.

Operates as a virtual, clinical-stage biopharmaceutical company with no approved products or product-sales revenue. Its work is centered in the United States and carried out through academic trial sites, contract providers and third-party manufacturers. Prospective revenue depends on clinical development, regulatory approval and product sales, partnerships, sublicensing or other strategic arrangements; much of the portfolio is covered by exclusive Cedars-Sinai license agreements.

Company facts

CEOJohn S. Yu, M.D.
ListedSep 16, 2024
ExchangeAMEX
HeadquartersLos Angeles, CA
CountryUnited States
Employees4
CIK0001962011
ISINUS48301N1046

Market cap$4.8M
EPS (ttm)−$1.11
P/E (ttm)−1.42
ROE-98.8%
P/B1.15
P/S0.00
Dividend yieldDiv yield
Beta1.76vs XLV −0.16

No analyst consensus on record.

Next report
Nov 13, 2026
estimated · in 71 days
EPS estimate
−$0.56
Revenue estimate
Fiscal quarter
Q3 FY26

EPSReportedEstimate

Feb '25Apr '25Aug '25Nov '25Mar '26May '26Aug '26Nov '26
Reported−$0.09−$0.08−$0.08−$0.07−$0.07−$0.08−$0.06Pending
Estimate−$0.06−$0.05−$0.06−$0.10−$0.02−$0.07−$0.09−$0.56
Surprise−43.8%−60.0%−33.3%+30.0%−275.3%−14.3%+33.3%

RevenueReportedEstimate

Feb '25Apr '25Aug '25Nov '25Mar '26May '26Aug '26Nov '26
ReportedPending
Estimate
Surprise
Estimate−$0.56
ReportedDue Nov 13, 2026
Estimate
ReportedDue Nov 13, 2026
View details

Debt to equity0.00%
Current ratio1,197.70%

ProfitabilityRevenueNet incomeNet margin

Q3 FY24Q4 FY24Q1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Revenue$0$0$0$0$0$0$0$0
Net income−$1.0M−$980.0K−$1.3M−$1.4M−$1.4M−$1.4M−$1.7M−$1.4M
Net margin

GrowthOperating income

Q3 FY24Q4 FY24Q1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Operating income−$383.0K−$1.4M−$1.3M−$1.5M−$1.4M−$1.6M−$1.6M−$1.4M
YoY growth

Balance sheet, Jun 30, 2026Cash & short-term investments $2.6M · Total debt $0 · Total assets $4.5M · Shareholders' equity $4.2M

Revenue
$0
Operating income
−$1.4M
Net income
−$1.4M
View details

No dividends on record.

Institutions11 holders · as of Mar 31, 20262.54%85.9K shares
Otherremainder97.46%3.30M shares

3.39M company shares as of Sep 3, 2026 · institutions as of Mar 31, 2026 · holders as of their latest filing

Two share counts disagree (3.39M in the company's Sep 3, 2026 report, 3.06M elsewhere); stakes use the report.

Top shareholders13F · 13D/G · Form 4

HolderStakeSharesEvidence
Vanguard Capital Management LLCInstitution
0.98%231,87813Fas of Mar 31, 2026
Geode Capital Management, LLCInstitution
0.47%111,29013Fas of Mar 31, 2026
Vanguard Fiduciary Trust CoInstitution
0.27%63,88413Fas of Mar 31, 2026
Aptus Capital Advisors, LLCInstitution
0.19%44,28613Fas of Mar 31, 2026
Sevenbridge Financial Group, LLCInstitution
0.19%44,28613Fas of Mar 31, 2026
See all 11

13F — a manager's quarterly holdings

Insider tradesForm 4

Nothing filed in the last 12 months.

View details

  • Johnson & Johnson

    Androgen-receptor therapies contest resistant-prostate treatment pathways.

  • Pfizer

    XTANDI contests androgen-receptor treatment in resistant prostate cancer.

  • Sanofi (ADR)

    JEVTANA is a later-line alternative in resistant prostate cancer.

  • Novartis (ADR)

    PLUVICTO and TABRECTA overlap in prostate and MET-positive lung cancer.

ComparePre-market

CompanyPriceChange
Kairos Pharma$1.69+4.97%$4.8M
Johnson & Johnson$275.21−0.01%$663.23B31.923.16.8+6.6%
Pfizer$28.99−0.14%$165.40B38.310.42.6+2.6%
Sanofi (ADR)$44.57+0.24%$106.78B78.21.9+11.2%
Novartis (ADR)$162.04−0.25%$308.79B24.517.35.6+0.9%
Median35.117.34.1+4.6%