LCTX · AMEX · Biotechnology

Lineage Cell Therapeutics

Develops off-the-shelf cell-replacement therapies for retinal, spinal-cord, hearing and corneal disease.

$1.11
After-hours close−0.00 (−0.45%)
At close$1.12(−3.88%)
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Profile

Lineage Cell Therapeutics, Inc.LCTXHealth Care

Develops off-the-shelf allogeneic cell-replacement therapies from pluripotent stem cells, generating collaboration and license-related revenue while candidates remain investigational. Its shared AlloSCOPE platform supports retinal, spinal-cord, hearing and corneal programs, with OpRegen licensed to Roche/Genentech.

Develops off-the-shelf, allogeneic cell-replacement therapies from pluripotent stem cells, using its AlloSCOPE manufacturing platform to create differentiated cells for damaged tissues. Revenue comes principally from collaboration, licensing and research obligations rather than product sales, with no approved therapy or established sales infrastructure.

The portfolio spans OpRegen retinal-pigment-epithelium cells for geographic atrophy, OPC1 oligodendrocyte progenitor cells for spinal-cord injury, ReSonance for hearing loss, COR1 for corneal disease, and early manufacturing and photoreceptor programs. Roche/Genentech holds worldwide rights to OpRegen, while internal programs share development and manufacturing work.

All therapeutic candidates remain investigational. Manufacturing is centered at its Jerusalem subsidiary, so commercialization depends on clinical results, regulatory review, specialized delivery, scalable cell production, collaborators and a single manufacturing site.

Company facts

CEOBrian M. Culley
ListedMar 5, 1992
ExchangeAMEX
HeadquartersCarlsbad, CA
CountryUnited States
Employees77
CIK0000876343
ISINUS53566P1093

Key statistics

Market cap$276.7M
EPS (ttm)−$0.1361
P/E (ttm)−8.16
ROE-71.1%
P/B4.55
P/S21.15
Dividend yield
Beta1.44vs XLV 0.45

Year to date −32.0% · Average volume (30d) 954.1K

Analysts

No analyst consensus on record.

Earnings

EPS

Estimate−$0.03
ReportedDue Nov 5, 2026

Revenue

Estimate$1.3M
ReportedDue Nov 5, 2026

History

Report dateEPS estEPSSurpriseRevenue estRevenueSurpriseNext session
Aug 6, 2026Q2 FY26−$0.03−$0.03−5.9%$1.8M$1.1M−42.0%−2.65%
May 12, 2026Q1 FY26−$0.02−$0.03−50.0%$3.6M$1.7M−52.1%−3.76%
Mar 5, 2026Q4 FY25−$0.04$0.00+109.2%$2.0M$6.6M+236.8%+0.54%
Nov 6, 2025Q3 FY25−$0.02−$0.13−550.0%$2.0M$3.7M+87.8%+1.73%
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Financial highlights

11 quartersQ1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Revenue$1.5M$2.8M$3.7M$6.6M$1.7M$1.1M
Gross profit$1.5M$2.7M$3.7M$6.5M$1.5M$882.0K
Operating income−$6.5M−$19.8M−$3.8M−$6.5M−$7.6M−$8.9M
Net income−$4.1M−$30.5M−$29.8M$851.0K−$4.8M$1.5M
Diluted EPS−$0.02−$0.13−$0.13$0.00−$0.02$0.01
Gross margin97.6%98.6%99.9%99.0%89.1%82.5%
Operating margin-433.1%-715.4%-102.9%-99.1%-440.2%-834.7%

Fiscal years (4-quarter sums)FY24 $9.5M · FY25 $14.6M

Revenue by product · Q2 FY26

Collaboration Revenues$943.0K · 100%

Revenue by geography · FY25

Non-US$2.5M · 100%

Balance sheet, Jun 30, 2026Cash & short-term investments $50.8M · Total debt $2.3M · Total assets $106.2M · Shareholders' equity $60.9M

Dividends

No dividends on record.

Ownership

Institutions 44.80%Insiders

Shares outstanding 249.30M · Float 236.53M · 94.9% free float

Top shareholders13F · 13D/G · Form 4

HolderShares% outstandingFormFiled
Neal C. Bradsher57.85M23.10%13DNov 14, 2025
Broadwood Capital Inc49.56M19.88%13FMay 15, 2026
BlackRock, Inc.13.19M5.30%13GJul 29, 2026
Chernett Jorey11.45M5.00%13GSep 26, 2025
Vanguard Capital Management LLC8.32M3.34%13FMay 15, 2026

Insider tradesForm 4

Nothing filed in the last 12 months.

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Peers

  • Biogen

    SYFOVRE is the leading commercial treatment for geographic atrophy.

  • AbbVie

    C5 inhibition for geographic atrophy, plus retinal gene therapy.

  • Regeneron

    Phase 3 C5 therapy and a large retinal-specialist franchise.

  • NervGen Pharma

    Neuroreparative recovery therapy for spinal-cord injury.

  • Sana Biotechnology

    Hypoimmune iPSC islet-cell therapy and cell-engineering overlap.

CompareAfter-hours close

CompanyPriceChange
Lineage Cell Therapeutics$1.11−0.45%$276.7M21.2−61.3%
Biogen$218.19−0.14%$32.28B38.716.53.2+3.4%
AbbVie$255.80+0.13%$451.38B72.016.87.0+10.2%
Regeneron$793.21−0.11%$81.82B19.613.15.3+16.7%
NervGen Pharma$2.270.00%$187.4M
Sana Biotechnology$3.95+0.51%$1.09B
Median38.716.55.3+10.2%