PTHS · AMEX · Biotechnology

Pelthos Therapeutics (PTHS)

Commercializes topical treatments for molluscum, impetigo, and head lice.

$25.91
Pre-market+0.89 (+3.56%)
At close$25.02(+0.81%)
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Pelthos Therapeutics Inc.PTHSHealth Care

Sells ZELSUVMI, an at-home topical treatment for molluscum contagiosum, while preparing XEPI for impetigo and XEGLYZE for head lice. Combines U.S. commercial operations with in-house active-ingredient manufacturing while licensing core NITRICIL intellectual property from Ligand.

Commercializes topical treatments for cutaneous infectious diseases, beginning with ZELSUVMI, an at-home nitric-oxide-releasing gel for molluscum contagiosum. XEPI for impetigo and XEGLYZE for head lice are FDA-approved acquired products in launch preparation, while CT2000 remains an early clinical program for eye pain.

Operates an in-house U.S. sales and market-access organization and manufactures ZELSUVMI's active ingredient in Durham; finished-drug production, logistics, and wholesale distribution rely on third parties. Revenue is currently tied to ZELSUVMI, with adoption dependent on physician and patient acceptance, pharmacy-benefit coverage, reimbursement, and sales-force execution. Core NITRICIL intellectual property is licensed from Ligand.

Company facts

CEOScott M. Plesha
ListedJul 2, 2025
ExchangeAMEX
HeadquartersDurham, NC
CountryUnited States
Employees92
CIK0001919246
ISINUS1711262048

Market cap$87.0M
EPS (ttm)−$41.93
P/E (ttm)−0.5969
ROE-218.9%
P/B−59.02
P/S2.01
Dividend yieldDiv yield
Beta0.45vs XLV 0.12

Price target$54.50+117.7%Avg of 3 analysts
ConsensusBuy3 of 3 analysts
Ratings

Target rangeAs of Sep 2, 2026

Latest analyst notes

DateFirmActionRatingPrior targetTarget
Aug 14, 2026OppenheimerReiterateOutperform$66$64
Aug 13, 2026Industrial Alliance SecuritiesTarget$45
May 15, 2026OppenheimerTarget$66

Next report
Nov 12, 2026
in 70 days
EPS estimate
−$2.90
Revenue estimate
$18.0M
Fiscal quarter
Q3 FY26

EPSReportedEstimate

Mar '25May '25Aug '25Nov '25Mar '26May '26Aug '26Nov '26
Reported−$3.23−$3.21−$5.38−$5.30−$6.87−$3.09−$6.62Pending
Estimate−$2.90−$5.82−$0.67−$3.95−$3.45−$2.82−$2.90
Surprise−10.7%+7.6%−691.0%−73.9%+10.4%−134.8%

RevenueReportedEstimate

Mar '25May '25Aug '25Nov '25Mar '26May '26Aug '26Nov '26
Reported$150.0K$7.4M$9.4M$10.9M$15.6MPending
Estimate$4.4M$4.4M$9.1M$10.4M$15.2M$18.0M
Surprise+68.7%+3.3%+4.5%+2.8%
Estimate−$2.90
ReportedDue Nov 12, 2026
Estimate$18.0M
ReportedDue Nov 12, 2026
View details

Current ratio198.20%

ProfitabilityRevenueNet incomeNet margin

Q3 FY24Q4 FY24Q1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Revenue$0$0$0$0$7.4M$9.4M$10.9M$15.6M
Net income−$1.7M−$1.9M−$2.0M−$3.4M−$16.2M−$21.7M−$10.2M−$23.4M
Net margin0.0%0.0%0.0%0.0%

GrowthOperating income

Q3 FY24Q4 FY24Q1 FY25Q2 FY25Q3 FY25Q4 FY25Q1 FY26Q2 FY26
Operating income−$2.0M−$1.8M−$1.8M−$3.2M−$15.4M−$12.0M−$13.1M−$17.3M
YoY growth

Balance sheet, Jun 30, 2026Cash & short-term investments $24.6M · Total debt $73.1M · Total assets $137.4M · Shareholders' equity −$1.5M

Revenue
$15.6M
Operating income
−$17.3M
Net income
−$23.4M
View details

No dividends on record.

Institutions17 holders · as of Mar 31, 202626.25%912.3K shares
Otherremainder73.75%2.56M shares

3.48M company shares as of Sep 3, 2026 · institutions as of Mar 31, 2026 · holders as of their latest filing

Top shareholders13F · 13D/G · Form 4

HolderStakeSharesEvidence
Murchinson Ltd.Institution
8.53%296,31413Fas of Mar 31, 2026
Ikarian Capital, LLCInstitution
7.38%256,59813Fas of Mar 31, 2026
Vanguard Capital Management LLCInstitution
2.68%93,09313Fas of Mar 31, 2026
Boothbay Fund Management, LLCInstitution
2.36%81,85813Fas of Mar 31, 2026
J. Goldman & Co LPInstitution
1.45%50,41513Fas of Mar 31, 2026
See all 18

13F — a manager's quarterly holdings

Insider tradesForm 4

Nothing filed in the last 12 months.

View details

  • Verrica Pharmaceuticals

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ComparePre-market

CompanyPriceChange
Pelthos Therapeutics$25.91+3.56%$87.0M2.0
Verrica Pharmaceuticals$5.42+3.44%$92.6M3.1−53.9%
Perrigo$14.05−2.97%$2.00B6.10.5−3.2%
Median6.11.8−28.5%